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C
GENETICSNAME: Rana Farrukh Hamid
ROLL NO: 15101560-036
PRESENTATION TOPIC: TYPES OF CHROMOSOMES +
KARYOTYPE/IDIOGRAM
SUBMIT TO: …………………………..
TYPES OF CHROMOSOMES
There are four basic types of chromosomes seen during anaphase.
These are:
1.TELOCENTRIC:
–No P arm, centromere is on the end
2. ACROCENTRIC:
–very small P arm, centromere is very near to the end
3. SUB-METACENTRIC:
–P arm just a little smaller than Q arm; centromere is in the
middle
4. METACENTRIC:
P and q arms are exactly the same length, centromere is
in exact middle of chromosome
• CHROMOSOME PARTS:
• Telomeres:
– chromosome tips
– Repeats
– Important in replication, protect from
diffusion with other chromosomes
• Centromeres:
– Highly condensed, middle region
– Also repetitive sequence
– Region where spindle fibers attach
– Pulling chromatids apart during mitosis
– Monocentric and Polycentric
• Chromomeres:
–during first phase (pachytene) of meiosis
– bead like structures called chromomeres.
• Satellite chromosomes:
– chromosomes that have satellite region and secondary constriction
KARYOTYPE OR IDIOGRAM
• It is the pictorial arrangement of total chromosomes of a cell
according to their size during metaphase of cell division.
• The diagrammatic representation of a chromosome complement
or karyotype is called karyogram or idiogram
• PREPERATION OF KARYOTYPE (TECHNIQUE):
When nuclei are in metaphase of mitosis it is easy to count and
characterize them.
A photograph of the entire set of chromosomes can be made
and pictures of individual chromosomes can be cut out
and pasted in an orderly arrangement.
Such a photograph reveals the number, shapes, and sizes of
chromosome in a cell which constitutes its karyotype.
Before arrangement After arrangement
• A karyotype may be symmetrical or asymmetrical. A perfectly symmetrical karyotype has all metacentric
chromosomes of the same size. They are known to be the primitive state from which more advanced
asymmetrical karyotype have evolved through structural changes.
• APPLICATIONS OF KARYOTYPE:
• Detection of chromosomal aberrations such as deletion, duplication, and translocation
• Loss of chromosome or addition of chromosome
• determine the risk of the individual and his future generations with such chromosomal variations
Chromosomes Types

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Chromosomes Types

  • 1. C GENETICSNAME: Rana Farrukh Hamid ROLL NO: 15101560-036 PRESENTATION TOPIC: TYPES OF CHROMOSOMES + KARYOTYPE/IDIOGRAM SUBMIT TO: …………………………..
  • 2. TYPES OF CHROMOSOMES There are four basic types of chromosomes seen during anaphase. These are: 1.TELOCENTRIC: –No P arm, centromere is on the end 2. ACROCENTRIC: –very small P arm, centromere is very near to the end 3. SUB-METACENTRIC: –P arm just a little smaller than Q arm; centromere is in the middle 4. METACENTRIC: P and q arms are exactly the same length, centromere is in exact middle of chromosome
  • 3. • CHROMOSOME PARTS: • Telomeres: – chromosome tips – Repeats – Important in replication, protect from diffusion with other chromosomes • Centromeres: – Highly condensed, middle region – Also repetitive sequence – Region where spindle fibers attach – Pulling chromatids apart during mitosis – Monocentric and Polycentric • Chromomeres: –during first phase (pachytene) of meiosis – bead like structures called chromomeres. • Satellite chromosomes: – chromosomes that have satellite region and secondary constriction
  • 4. KARYOTYPE OR IDIOGRAM • It is the pictorial arrangement of total chromosomes of a cell according to their size during metaphase of cell division. • The diagrammatic representation of a chromosome complement or karyotype is called karyogram or idiogram • PREPERATION OF KARYOTYPE (TECHNIQUE): When nuclei are in metaphase of mitosis it is easy to count and characterize them. A photograph of the entire set of chromosomes can be made and pictures of individual chromosomes can be cut out and pasted in an orderly arrangement. Such a photograph reveals the number, shapes, and sizes of chromosome in a cell which constitutes its karyotype.
  • 6. • A karyotype may be symmetrical or asymmetrical. A perfectly symmetrical karyotype has all metacentric chromosomes of the same size. They are known to be the primitive state from which more advanced asymmetrical karyotype have evolved through structural changes.
  • 7. • APPLICATIONS OF KARYOTYPE: • Detection of chromosomal aberrations such as deletion, duplication, and translocation • Loss of chromosome or addition of chromosome • determine the risk of the individual and his future generations with such chromosomal variations