The document discusses the AMPLATZERTM AMULET device, which is a percutaneous transcatheter device intended for closure or occlusion of cardiac structures not involving the septal wall, including the left atrial appendage (LAA). The device requires careful patient selection, imaging, and sizing. The device is contraindicated for patients with intracardiac thrombus, active endocarditis or infections. Measurements of the LAA from previous studies are provided, showing variability in size and morphology between individuals. Potential anatomical relationships that could be at risk during LAA occlusion are identified.