chemistry and synthesis of methotrexate.pptx

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Methotrexate is a chemotherapy drug used to treat cancer and autoimmune diseases. It works by inhibiting dihydrofolate reductase, an enzyme involved in cell division. The document discusses the chemistry and synthesis process for producing methotrexate, which involves multiple chemical reaction steps to build up the molecule from simpler starting materials.

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chemistry and synthesis of methotrexate.pptx

-a broad-spectrum antibiotics. -It is commonly used to treat acne, infection, and other infections caused by bacteria. -The first of these compounds was chlortetracycline followed by oxytetracycline and tetracycline. Tetracycline is a broad-spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria, indicated for use against many bacterial infections. It is a protein synthesis inhibitor. It is commonly used to treat acne today, and, more recently, rosacea, and is historically important in reducing the number of deaths from cholera. Tetracycline is marketed under the brand names Sumycin, Tetracyn, and Panmycin, among others. Actisite is a thread-like fiber formulation used in dental applications. It is also used to produce several semisynthetic derivatives, which together are known as the tetracycline antibiotics. The term "tetracycline" is also used to denote the four-ring system of this compound; "tetracyclines" are related substances that contain the same four-ring system.

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