This document defines several terms related to literacy, including literacy, illiteracy, low literacy, health literacy, functional illiteracy, readability, comprehension, and numeracy. It discusses literacy relative to oral instruction and computer instruction. It provides statistics on the scope and incidence of literacy problems in the US and trends associated with literacy problems. It identifies groups at risk for low literacy and dispels common myths. It discusses clues that can indicate low literacy and the impact of illiteracy on motivation and compliance. It covers ethical, legal and financial concerns as well as trends increasing the need for patient education. It examines the readability of printed education materials and tools to measure readability and assess comprehension.