The document summarizes the history of conflict between Native Americans and settlers/the U.S. government from the 15th century to the 1970s. It describes how Native populations declined dramatically due to disease, starvation, and warfare as settlers took over their lands. The government enacted policies like the Indian Removal Act and reservation system that disrupted Native ways of life. Native groups resisted through events like the Battle of Little Bighorn and Wounded Knee Massacre. The document also discusses the later assimilationist policies and the rise of the American Indian Movement to advocate for Native rights.