Cesarean hysterectomy is really two separate operations: cesarean section and hysterectomy. Cesarean hysterectomy can be accomplished through most abdominal wall incisions. A vertical incision provides best exposure, but often when performed as an emergency a transverse incision has been used and may be adequate.
THIS WAS PRESENTED AT SAFOG MOGS "SMART CONFERENCE "IN MUMBAI
PREPARED WITH HELP OF DR SUCHITRA PANDIT,DR CN PURANDARE AND DR ALPESH GANDHI.....VIDEOS CAN BE SEEN AT U TUBE
Sickle cell anemia is an autosome linked recessive trait that can be transmitted from parents to the offspring when
both the partners are carrier for the gene (or heterozygous). The disease is controlled by a single pair of allele, HbA
and HbS. Out of the three possible genotypes only homozygous individuals for HbS (HbS, HbS) show the diseased phenotype. The ability to predict the clinical course of SCD during pregnancy is difficult. It is mandatory to follow up the patient closely from the very beginning i.e. from preconception to antenatal till labor. SCD is associated with both maternal and fetal complications and is associated with an increased incidence of perinatal mortality, premature
labor, fetal growth restriction and acute painful crises during pregnancy.
THIS WAS PRESENTED AT SAFOG MOGS "SMART CONFERENCE "IN MUMBAI
PREPARED WITH HELP OF DR SUCHITRA PANDIT,DR CN PURANDARE AND DR ALPESH GANDHI.....VIDEOS CAN BE SEEN AT U TUBE
Sickle cell anemia is an autosome linked recessive trait that can be transmitted from parents to the offspring when
both the partners are carrier for the gene (or heterozygous). The disease is controlled by a single pair of allele, HbA
and HbS. Out of the three possible genotypes only homozygous individuals for HbS (HbS, HbS) show the diseased phenotype. The ability to predict the clinical course of SCD during pregnancy is difficult. It is mandatory to follow up the patient closely from the very beginning i.e. from preconception to antenatal till labor. SCD is associated with both maternal and fetal complications and is associated with an increased incidence of perinatal mortality, premature
labor, fetal growth restriction and acute painful crises during pregnancy.
4 cases of pelvic mass are discussed .Adnexal mass invilves masses arisinf from ovary,fallopian tube,uterus,bowel and some miscellenious masses.USG is used to detect its size and the origin.Histopathological findings are diagnostic.
Presentation on the description of normal and abnormal uterine bleeding, menstrual cycle, FIGO classification with PALM-COEIN, common differentials of AUB, assessment, diagnosis, and management.
4 cases of pelvic mass are discussed .Adnexal mass invilves masses arisinf from ovary,fallopian tube,uterus,bowel and some miscellenious masses.USG is used to detect its size and the origin.Histopathological findings are diagnostic.
Presentation on the description of normal and abnormal uterine bleeding, menstrual cycle, FIGO classification with PALM-COEIN, common differentials of AUB, assessment, diagnosis, and management.
Multidisciplinary case chronic myelogenous leukemia in pregnancyDR MUKESH SAH
Pregnancy and CML
While pregnancy in and of itself does not affect the course of CML, there is a risk for maternal disease progression if CML remains untreated for the duration of pregnancy. Unfortunately, treatment of CML during pregnancy is complicated due to the teratogenic nature of TKIs
Cervical incompetence is the inability for the cervix to retain an intra-uterine pregnancy till term as a result of structural and functional defects of the cervix
Optimising Delivery Of 1kg Fetus - Special Considerations.pptxNiranjan Chavan
After an uncomplicated vaginal birth in a health facility, healthy mothers and newborns should receive care in the facility for at least 24 hours after birth.
This Note is Prepared by A OBGYN resident @ SPHMMC, Addis Ababa, Ethiopia (March 2019)
For further notes, you can join us on our Telegram group @obgynsphmmc2019
Tel: +251920257863
Irritable bowel syndrome is a common condition affecting the digestive system.
Symptoms of irritable bowel syndrome include stomach cramps, bloating, diarrhoea and constipation. These may come and go over time.
Making changes to your diet and lifestyle, like avoiding things that trigger your symptoms, can help ease irritable bowel syndrome.
blockage or problem in the urinary tract can mean urine is unable to drain from the kidneys or is able to flow the wrong way up into the kidneys. This can lead to a build-up of urine in the kidneys, causing them to become stretched and swollen.
An injury higher on the spinal cord can cause paralysis in most of your body and affect all limbs (tetraplegia or quadriplegia). A lower injury to the spinal cord may cause paralysis affecting your legs and lower body (paraplegia)
Scoliosis is the abnormal twisting and curvature of the spine. It is usually first noticed by a change in appearance of the back. Typical signs include: a visibly curved spine. one shoulder being higher than the other.
Osteoarthritis (OA) is the most common form of arthritis. Some people call it degenerative joint disease or “wear and tear” arthritis. It occurs most frequently in the hands, hips, and knees.
With OA, the cartilage within a joint begins to break down and the underlying bone begins to change. These changes usually develop slowly and get worse over time. OA can cause pain, stiffness, and swelling. In some cases it also causes reduced function and disability; some people are no longer able to do daily tasks or work.
About 4 out of 5 cases of acute pancreatitis improve quickly and don't cause any serious further problems. However, 1 in 5 cases are severe and can result in life-threatening complications, such as multiple organ failure. In severe cases where complications develop, there's a high risk of the condition being fatal.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
2. General Data
• Patient J.G
• 41 years old
• Female
• Married
• Born on February 2, 1976
• House wife
• Balungao, Pangasinan
• Admitted on October 10, 2017 for the first time in
R1MC
06/05/2020 2
4. History of Present Illness
• 4 days Prior to admission
the patient
experienced headache
with associated dizziness,
accompanied by vaginal
spotting
• Consult in a private
institution
• She was noted to have
high Blood Pressure and
was advised for admission
but refused
• Home Medication given
was Methyldopa 250 mg
every 8 hours
06/05/2020 4
5. History of Present Illness
• The patient had temporary
relief of symptoms until
• 3 hours Prior to admission
the patient then again
experienced headache and
dizziness with associated
body weakness, (-)
hypogastric pain, (-) blurring
of vision, (-) vomiting, (-)
vaginal bleeding/discharge
• Which prompted consult at
R1MC hence admission
06/05/2020 5
6. Past Medical History
• Patient has no known allergies to any medication or food no
know history of diabetes
• Patient cannot recall if she had any childhood diseases.
• The patient has no previous Operation
• Patient was diagnosed to have Myoma Uteri (subserous) On
August 7, 2017 via Ultrasound
06/05/2020 6
7. Family History
• No Heredofamilial disease were recalled by the patient
06/05/2020 7
8. PERSONAL/SOCIAL HISTORY
• The patient is a college graduate. She’s now a plain housewife
living with her husband and granddaughters. Her diet is
usually composed of meat, vegetables, and rice. She doesn’t
smoke nor drink.
06/05/2020 8
9. Obstetrics History
Menarche- 12 y/o
Interval- Regular
Duration- 5 days
Amount- 3-5 pads/day
Symptoms- (+) dysmenorrhea
Sexual hx- 17 y/o
No. of partner- 1
Family planning- none
Papsmear – none
PNCU – 5x BHC and
private institution
06/05/2020 9
10. Obstetrics History
LMP- Dec 8, 2016
EDC- Aug 15, 2017
AOG- 38 5/7 weeks
G3P1(1011)
G1 –2004 , Term, NSD, Home
Delivery , Female, alive
G2 – 2009, Miscarriage
G3 -Present pregnancy
06/05/2020 10
11. Physical Examination
• Patient is conscious, coherent not
in cardio respiratory distress
– Current BP: 200/ 100 mmHg
– Highest BP:220/100 mmHg
– Goal Bp:176/80 mmHg
– CR:94 bpm RR:20 T:36.5C
• (-)pallor (-) jaundice (-) cyanosis
• Pink palpebral conjunctiva
anicteric sclera, (-) periorbital
Edema
• Symmetrical chest expansion, no
retractions, clear breath sounds
• Adynamic precordium, normal
rate, regular rhythm, no murmur
06/05/2020 11
12. Physical Examination
Abdomen globular, normoactive bowel sounds, soft nontender,
with palpable nodular masses at periumbilical and infraumbilical
area measuring 10x8 and 8x5cm
Extremities: (+) bipedal edema, pitting, grade 1
FH- 33cm FHT-132 bpm
IE- Cervix closed, uneffaced, (-) SHOW
LM1- Cannot Fully determine due to Presence of Myoma
LM2- Small irregular soft mass at right maternal side, fetal back at
left maternal side
LM3- Round ballotable hard mass
LM4-
06/05/2020 12
13. Salient features
• Subjective
– Headache
– Dizziness
– Vaginal bleeding
– Gradually
increasing Mass
at abdomen
• Objective
– Elevated Blood
Pressure: 200/100
– Multiple Palpable
Mass at the
periumbilical and
infraumbilical area
– (+) Fetal movement
– (+)Fetal Heart tone
– (+) bipedal edema
– Urinalysis: ++
proteinuria
06/05/2020 13
14. Admitting Diagnosis
G3P1(1011) PU 38 5/7wks AOG, Cephalic not in Labor, Pre-
eclampsia with severe features, Myoma uteri
06/05/2020 14
15. On the day of admission
10/10/17 (6:00 am) First Hospital Day
• Admitted at Labor room
• Diagnostics done
-Cbc typing -Urinaysis -FBS
-HbsAg -VRDL/RPR -HBA1c
-Electrolytes -LDH -RBS
-BUN, Crea -SGOT, SGPT
• IVF: D5 LRS 1L x 20ugtts/min
• MgSo4 4 grams SIVP then 5grams deep IM each buttocks
• Hydralazine 5mg IV
• Methyldopa 250mg/tablet 2 tablet q6
• Insert IFC aseptically
• Hooked on O2 at 3-4 lpm via NC
• Position patient to Left lateral decubitus
• Monitored VS, FHT and Progress of Labor
06/05/2020 15
20. Ultrasonography
• August 7 ,2017
– Within a gravid uterus single Male fetus in breech presentation with good
cardiac activity
– Biometric Measurement
• BPD: 7.49cm= 30 weeks 0 days
• HC: 27.61cm= 30 weeks 1 day
• AC: 26.12cm = 30 wes 2 days
• FL: 5.89 cm = 30 weeks 5 days
• EFW: 1,568 grams
– Expected date of delivery October 14 2017
– Fetal heart rate 144 bpm
– Placenta located anteriorly with grade 2 in maturity
– Hypoechoic nodule in the anterior wall of the Uterus Measuring 2.82 x2.37
cm, 5.49x 3.91 cm, and 5.24 x 4.22cm
06/05/2020 20
21. On the day of Admission
• 10/10/17 (9:00 am)
– KCL Drip Started (PNSS 1L + 40 Meqs) to run for 6 hours
– Scheduled for LTCS I ( Pre-eclampsia w/ severe features,
Uncontrolled BP)
– Secure Consent
– Notify OR and Anesth on duty
– Cefuroxime 1.5 gm iv (-) ANST now then 750 q 8 hours
– Secure 1 unit PRBC for possible OR use
06/05/2020 21
22. Course in the Ward
• 10/10/17
– Operation started at 11: 25 am
– Operation ended at 12: 50 PM
06/05/2020 22
23. Operation done
‘E’ LTCS followed by Total Abdominal
Hysterectomy with Bilateral Salphingo-
oophorectomy
06/05/2020 23
25. Intraoperative
On laparotomy a gravid term size uterus was exposed with
formed lower uterine segment, LTCS was done extracting to a
live baby boy in cephalic presentation; amniotic fluid clear and
adequate with AS 8/9 in 1 and 5 minutes if life. Placenta located
anterofundally. On further exploration, multiple myoma was
noted on the anterior wall, the two largest mass approximately
10x10 cm and at the posterior wall, the largest mass was also
measured about 8x8cm. Both fallopian tubes were normal but a
multiple Endometrial implants were noted in the ovaries. Then
proceeded with total abdominal Hysterectomy with bilateral
salpingo-oophorectomy.
OR started: 12:34pmEnded: 1:52pm
EBL: 800cc UO: 200cc
06/05/2020 25
29. Gross Examination:
• The uterus measured 27X20X17CM, Multiple Intramural
Masses at the anterior wall M1:9x6x4cm M2: 10x8x4cm M3:
3x3x3 cm, on the posterior wall M1: 8x7x3cm M2: 5x5x3cm,
M3: 3x3x2cm. On cut section of masses it reveals tan colored
with whorl like tissue pattern.
• Endometrial canal: 19 CM Cervix 6x6x3 cm
• Ovary Right: 3x3x1 cm, , fallopian tube right 14x1cm
• Ovary Left: 3x3x1cm, fallopian tube Left 13x1cm
06/05/2020 29
30. M4 8x7x3 cm
M5 5x5x3 cm
M6 3x3x2 cm
M6
M4 M5
06/05/2020 30
32. Final Diagnosis
• G3P2 (2012) PU term cephalic live birth delivered via LTCS I for
Pre-eclampsia with severe features under SAB to a baby boy
BW2770gm BL51cm AS:8/9 BS: 38wks AGA followed by total
abdominal Hysterectomy with bilateral salpingo-
oophorectomy, Multiple Myoma(Intramural and Subserous),
pelvic endometriosis
06/05/2020 32
34. UTERINE FIBROIDS (LEIOMYOMATAS)
• Uterine fibroids, also known as uterine leiomyomas
• Benign Smooth Muscle Tumor of the Uterus
• They are benign neoplasms composed of disordered
“myofibroblasts”
• the Most Common gynecological tumours
• Occurring in about 30% of women above the age of 30 years.
06/05/2020 34
36. Epidemiology
• Most frequent pelvic tumors and most common tumor in
women
• Highest prevalence occurring during 5th decade
• In general a third of myomas become symptomatic
06/05/2020 37
37. Risk Factors
• Increasing age
• Early menarche
• Low parity
• Tamoxifen use
• Obesity
• High fat diet
06/05/2020 38
39. Clinical Presentation
• Pressure due to enlarging pelvic mass
• Dysmenorrhea
• Abnormal uterine bleeding
• Increase in abdominal girth
• Urinary frequency or urgency
• Asymptomatic in over 2/3 of women with uterine myoma
06/05/2020 40
41. Differential Diagnosis
• Causes of symmetrically enlarged uterus:
– Pregnancy
– Subinvolution of the uterus.
– Submucous or interstitial fibroid.
– Adenomyosis uteri.
– Carcinoma or sarcoma of the uterus.
• Causes of asymmetrically enlarged uterus:
– Subserous fibroid.
– Localized adenomyosis.
– Ovarian, tubal, or broad ligamentary swelling.
06/05/2020 42
42. Management
• Conservative Management
– small asymptomatic fibroid,
– fibroid in pregnancy or puerperium.
• Just keep observation every 6 months.
• Beware of underlying and/or associated
pathology
06/05/2020 43
43. Medical Treatment:
• Lines of treatment:
– Symptomatic:
• Correction of anemia,
• haemostatics,
• analgesics, and anti-spasmodics (anti-PG).
– Anti-estrogens:
• large dose of progesterone,
• Tamoxifen, Danazol,
• LH-RH analogues
– useful in decreasing the size and vascularity of the tumor by 50%
which is beneficial before myomectomy
06/05/2020 44
44. Surgical Management
•Indications:
•Symptomatic cases or uterus larger than 12
weeks size.
•Suspected malignancy (rapidly enlarging or
post-menopausal growth).
•Multiple huge fibroids liable to complications.
•Infertility.
06/05/2020 45
46. Principle of Myomectomy
•Myomectomy aims at
– removal of all the myomas,
– with conservation of a functioning uterus to preserve
the reproductive function.
•Generally the morbidity is higher than those with
hysterectomy.
– It is associated with much blood loss
– Liability of recurrence of fibroid.
•Myomectomy is better reserved only for those
keen to preserve the reproductive function.
06/05/2020 47
47. Principle of Hysterectomy
• Patient around 40 years, and completed her family.
• Severe bleeding during myomectomy.
• Major damage of the uterus by myomectomy which
affects its function for pregnancy.
• Recurrent fibroids.
• Asymptomatic myomas wherein uterus reahed size
of 14-16 weeks AOG
• Suspicious of malignancy – rapid growth after
menopause
06/05/2020 49
48. What is the effect of Fibroid on
Pregnancy and Pregnancy on Fibroid?
eMedMD.
com
06/05/2020 51
49. What is the effect of Fibroid on Pregnancy and
Pregnancy on Fibroid?• A Fibroid or Fibroids are very often discovered in the womb
(uterus) during a pelvic examination or more frequently during
a routine ultrasound scan when a woman is pregnant.
• It has been found that about a third of fibroids may enlarge
during the first three months (known medically as the first
trimester) of pregnancy.
06/05/2020 52
50. What is the effect of Fibroid on Pregnancy and
Pregnancy on Fibroid?
• It has been found that between 10% and 30% of women with
fibroids have problems or complications during their
pregnancy.
• It is hypothesised that mechanical obstruction or impaired
distensibility (stretchability) of the uterus may explain some of
the problems caused by fibroids.
06/05/2020 54
51. What is the effect of Fibroid on Pregnancy and
Pregnancy on Fibroid?
• In early Pregnancy
– Miscarriage
– Bleeding
06/05/2020 55
52. What is the effect of Fibroid on Pregnancy and
Pregnancy on Fibroid?
• In Late Pregnancy
– Preterm labor and preterm premature rupture of membranes
– Placenta abruption
– Placenta previa
– Fetal growth restriction and fetal anomalies
06/05/2020 56
53. What is the effect of Fibroid on Pregnancy and
Pregnancy on Fibroid?
• In labor and delivery
– Malpresentation, caesarean section and labour dystocia
– Retained placenta
– Postpartum hemorrhage
06/05/2020 57