This document provides an overview of the peoples and civilizations that existed in North and South America before European contact, including hunting and gathering societies as well as more advanced civilizations like the Maya, Aztec, and Inca. It then discusses the factors that drove European exploration across the Atlantic starting in the late 15th century, focusing on Spain's conquest of indigenous American empires and the establishment of colonies by other European powers like England and France in the following centuries. The document examines the complex interactions and exchanges that occurred between European colonizers and native populations as a result of this contact and colonization.