2. Objectives
ā¢ Demonstrate knowledge of the anatomy and
physiology of human lactation
ā¢ Demonstrate the ability to apply your acquired
knowledge in educating women in the antenatal
and postnatal periods with regards to the
production of breastmilk
ā¢ Demonstrate the ability to provide support on
breastfeeding techniques
ā¢ Demonstrate knowledge of the strategies for
protection and promotion of breastfeeding
ā¢ Identify advantages of and contraindications to
breastfeeding
3. Introduction
ā¢ To date there is no true substitute for breastfeeding
ā¢ Replacement feeding has been adapted to suit various
special needs of infants
ā¢ Breastfeeding is the mother's choice, and she needs to
be supported in whatever choices she makes
ā¢ In places where breastfeeding is universal or the
norm,this needs to be protected
ā¢ As midwives we have thorough knowledge of the
anatomy and physiology of the breast and other
factors that might affect a womans feeding choice
5. Terminology
ā¢ Lactogenesis: Onset of milk secretions through a
series of mammary epithelial cellular changes
whereby alveolar cells are converted from a non-
secretory state to a secretory state
ā¢ Galactopoiesis:Requires prolactin for milk secretion
and oxytocin that is critical for the breastmilk let-
down reflex in response to suckling
ā¢ Hypergalactia: Refers to over production of
breastmilk
ā¢ Galactorrhoea: Abnormal milk production
ā¢ Agalactia: Indicates an inability to lactate
6. The
physiology of
lactation:
Hormonal
influences on
the breast
ā¢ Oestrogen and progesterone are
responsible for breast development
during pregnancy and lactation
ā¢ During pregnancy prolactin and
oestrogen increases the development
of the duct system of the breasts
ā¢ Prolactin is responsible for secretion of
milk
ā¢ Secretory effect of prolactin is inhibited
by high levels of oestrogen and
progesterone during pregnancy
7. Hormonal
influences on
the breast
ā¢ With the delivery of the
placenta oestrogen
and progesterone drops
ā¢ Prolactin increases ā
promoting milk
production
ā¢ Initiating lactation
8. Hormonal
influences on
the breast
ā¢ PROLACTIN:
ā¢ Anterior pituitary gland
ā¢ Let down reflex (secretion of
milk)
ā¢ OXCYTOCIN:
ā¢ secreted when baby suckle
ā¢ By the Posterior pituitary gland
ā¢ Involution (contraction of uterus)
9. Hormonal
influences on the
breast
ā¢ Oxytocin is stimulated
when the baby is suckling
āhearing/seeing baby
ā¢ It causes the
myoepithelial cells to
ā¢ contract and allows the
milk to be expressed -LET
DOWN REFLEX
10. Lactogenesis (Initiation and production of
breastmilk)
ā¢ Stages of milk production are colostrum, transitional milk and mature milk
ā¢ Colostrum is present during pregnancy and the 1st food for the infant
ā¢ Thick yellowish fluid rich in Vit A and continues to secrete 2 weeks postpartum abd has
the following benefits
ā¢ Provides a continuation of the immunity that was available to the fetus via placenta
ā¢ Rich in immunoglobins which protect the infant from viruses and infections
ā¢ It is high in protein, fat soluble vitamins and minerals
ā¢ High amounts of sodium,potassium,chloride and cholestorol to encourage development
of the baby's heart, brain and CNS
11. Lactogenesis
(cont.)
ā¢ Volume varies between mothers and is about 2-
10ml per feed per day for 1st three days
ā¢ Transitional milk produced between day 7-10 for
two weeks
ā¢ Gradually changes to mature milk
ā¢ Mature milk will be present after 14-21 days and
looks watery rather than creamy because of the
high concentration of whey
ā¢ Breastmilk meets the requirements of the baby,
and no added water is need
ā¢ When hormones are released, lactation starts
ā¢ Maintained by stimulation of the nipple and
emptying of the breast
12. Lactogenesis
(cont.)
ā¢ Milk production depends on suckling that
releases the hormones for milk production
ā¢ Rate of milk synthesis is 11-58
ml/hour/breast
ā¢ Regular emptying of the breasts is main
way to produce more milk
ā¢ The composition of milk is influenced by
the mother's fluid and food intake
13. Synthesis of
human milk
ā¢ Increased blood flow to the
breasts,GIT,liver and increased cardiac
output
ā¢ Increase in metabolic rate āplace burden
on thyroid gland and the
ā¢ Thyroid gland is enlarged during lactation
ā¢ Milk is synthesised in the alveolar cells
ā¢ The epithelial cells of the milk gland
contain stem cells
ā¢ And are highly specialised at the terminal
duct
14. Synthesis of
human milk
(cont.)
ā¢ Breastmilk changes through the course of a feed
and throughout the day
ā¢ Secreted as foremilk 1st and satisfies the baby's
thirst
ā¢ Hindmilk is produced as the feeding progresses
and is high in fat and calories to promote growth
and development of the baby
ā¢ Preterm milk differs from full term milk offering
preterm babies longer access to colostrum
ā¢ It contains higher levels of immunoglobin A (IgA)
triglycerides and long chain fatty acids
ā¢ Protects against necrotizing enterocolitis
(NEC)which is a fatal condition in premature babies
15. Properties
of human
milk
ā¢ Immunological properties: Decreases the infant's
chances of developing allergies, respiratory
infections, otitis media and asthma
ā¢ Enzymes: Enters mothers' milk from the maternal
intercellular fluid and others are broken down in
the mammary cells. Assists with fat metabolism
ā¢ Electrolytes, minerals and water: Human milk as
lower monovalent ions and higher lactose content
than the mother's plasma (distinguishes human
milk from that of other species)
ā¢ Glucose metabolism: Key function in milk
production and main source of energy
ā¢ Fats: Alveolar cells are able to synthesise short-
chain fatty acids
16. Properties of human
milk (cont.)
ā¢ Protein (nitrogen): Produced by free amino acids in the
cells. Protein is 75% of total nitrogen in human milk vs 95%
in cows' milk. Human milk is low in curd, due to high whey
content and is easily digested. If breastmilk is left standing
the clear fluid seen is whey
ā¢ Vitamin content: Dependent on the nutrition and vitamin
intake of the mother and can be critically low if mother is
malnourished
ā¢ Nucleotides: Important in protein synthesis and provide
energy for biosenthesis.Play a role in anabolism and
growth. Failure to thrive on breastmilk may be because of
low nucleotides in the breastmilk
17. Advantages of breastmilk
ā¢ Breastfed babies have a decrease chance of developing:
ā¢ Respiratory and ear infections
ā¢ Allergies and atopic diseases
ā¢ Asthma
ā¢ UTI
ā¢ Diarrhoeal infections, gastrointestinal reflux and NEC
ā¢ Bacterial meningitis
ā¢ Sudden infant death syndrome (SIDS)
ā¢ Childhood lymphomas Hodgkins's disease and leukaemia
18. Discontinuation/avoidance of
breastmilk
ā¢ Agalactia (inability to breastfeed):Breast surgery,
retained placenta,Sheehans syndrome where a women
fails to lactate
ā¢ Suppression of breastmilk: Suppressed by hormonal
contraception,HIV,drugs or prescription medication that
may affect the baby
ā¢ Replacement feeding and milk banks:Should a mother
be unable to breastfeed replacement feeding may be an
option. Infants can get the benefits of breastmilk
through a certified donor milk banks (DMB)
ā¢ Social factors: Differs between cultures and
socioeconomic groups
ā¢ Psychological factors: May include a woman's own
relationship with her mother, relationship with partner,
whether pregnancy was planned or unplanned
19. Contamination of
breastmilk
ā¢ Reflects contamination found in the
environment
ā¢ Monitored throughout the world to
determine the level of toxins in the
environment