Recently, New York-based BOC Sciences announced that it has upgraded its product list of organelle fluorescent probes. Visit https://probes.bocsci.com for more information.

1. BOC Sciences Upgrades Organelle Fluorescent Probe Product List
Organelle fluorescent probes are an important tool in cytology research. Recently, New York-based
BOC Sciences announced that it has upgraded its product list of organelle fluorescent probes.
In the field of cell biology, fluorescence excitation and detection have little effect on cell morphology
and physiology, so it deserves to be one of the preferred tracer methods for studying cell structure and
function. As an important tool for studying cell structure and function, fluorescent probes can be
selectively combined with organelles. Using laser scanning confocal microscope to observe the
combined cells, high-definition images of subcellular structures can be obtained, and the morphological
changes of living cells can also be dynamically observed. The combination of immunohistochemistry
and in situ hybridization technology can be used to quantitatively study the pathological and
physiological changes of cells from the molecular biology level, and it can also be used to analyze cell
energy metabolism, signal transduction, membrane potential changes, apoptosis, and to identify cell
types.
BOC Sciences provides the following series of fluorescent probes for cell structures and organelles:
Lysosomal fluorescent probe
Fluorescent probes can use the acidic physiological environment of the lysosome, the material
metabolism function of the lysosome, and the special membrane protein or hydrolase of the lysosome
to specifically locate the lysosome. The detection objects of fluorescent probes targeting lysosomes
include reducing species, reactive oxygen species, reactive nitrogen species, hydrogen ions, metal ions,
anions and biological enzymes, as well as microenvironments such as temperature, viscosity, polarity,
and pH.
Mitochondrial Fluorescence Probe
Mitochondrial selective fluorescent probes and dyes can be used to monitor cell morphology and
organelle function. These probes and dyes can mark the activity of mitochondria and can be used to
observe the physiological effects of certain drugs that can change the function of mitochondria. Typical
mitochondrial fluorescent probes are jc-1 and rhodamine 123 and so on.
Endoplasmic reticulum fluorescent probe
The endoplasmic reticulum fluorescent probes are highly selective for the endoplasmic reticulum
staining of living cells. And the endoplasmic reticulum fluorescent probes can be divided into two
categories, one category is single-function endoplasmic reticulum localization probes, and the other is
multifunctional endoplasmic reticulum probes. They have multiple functions of locating the
endoplasmic reticulum and detecting the morphology and environment of the endoplasmic reticulum
and the active species in it.
Golgi fluorescent probe
Typical Golgi fluorescent probes include C6 NBD Ceramide and BODIPY Fl C5-Ceramide, which are
suitable for staining live and fixed cells.
Nuclear fluorescent probe

2. Nuclear dyes/probes play an important role in cell biology and histology research. According to the
different permeability of cell membrane, nuclear dyes/probes can be divided into two types: permeable
nuclear dyes/probes and non-permeable nuclear dyes/probes. Cell-permeable nuclear dyes/probes
include Hoechst stain and non-cell permeable nuclear dyes/probes include DAPI.
Cell membrane fluorescent probe
DiI, DiO, DiD and DiR dyes are common lipophilic fluorescent dyes used to label membranes.
Cytoplasmic fluorescent probe
In research on cell proliferation and viability, cytoplasmic dyes can be used to monitor the morphology
and location of cells. Cytoplasmic fluorescent probes include Calcein Blue AM, BCECF, CFDA-SE,
etc.
For more information about fluorescent probes for cells and organelles, please visit the website:
https://probes.bocsci.com/application/cell-and-orgenella-stains.html.
About BOC Sciences
BOC Sciences grasps the urgent needs of the market and to develop its fluorescent probe market by
relying on its core leading technologies. BOC Sciences has a professional R&D team that can provide
customers in more than 160 countries/regions with low-cost, wide-ranging, and effective fluorescent
probes, striving to become a leader in the probe industry.