The keynote address by Bob Spence discusses the emergence of engineered and collaborative unstructured learning in corporate settings, highlighting the 70:20:10 rule which emphasizes the significance of informal, on-the-job learning. It addresses various learning strategies, including structured and unstructured approaches, performance support, and the importance of engagement and innovation in driving business growth. The document concludes with a focus on measuring learning success and the need for a balanced design in professional development.