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*Create fun conversations.* Stickers, GIFs, Poptexts & more. Download Bobble Keyboard Now 👇
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X- Ray physics- X-Ray Tube, Transformer, Generator and Rectifiers by kajalsra...DrKajalLimbad
X-Ray physics including x-ray tube, transformer, generator, and rectifiers. physics made an easy
Note: this ppt has many animations that may not be appreciated over here. Request original ppt at kajalsradiology@gmail.com
X- Ray physics- X-Ray Tube, Transformer, Generator and Rectifiers by kajalsra...DrKajalLimbad
X-Ray physics including x-ray tube, transformer, generator, and rectifiers. physics made an easy
Note: this ppt has many animations that may not be appreciated over here. Request original ppt at kajalsradiology@gmail.com
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
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We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
4. The inner-shell electron is tightly bound to the nucleus. Thus, K-shell
electrons or inner-shell electrons have a higher binding energy than
outer-shell electrons. Tungsten is a large atom with 74 orbiting
electrons. As atomic complexity increases, the electrons in any given
shell are more tightly bound than in a less complex atom.
When the projectile electron ionizes a target atom by removing a K-
shell electron, a temporary electron void is produced in the K-shell. This
is a highly unnatural state for the target atom and is corrected by an
outer-shell electron falling into the void in the K shell. Tungsten, for
example, has electrons in shells out to the P shell, and when a K-shell
electron is ionized, its position can be filled with electrons from any of
the outer shells. The transition of an orbital electron from an outer shell
to an inner shell is accompanied by the emission of an X-ray.
X-ray Basics
5.
6.
7. The production of heat and characteristic X-rays involves interactions between the
projectile electrons and the electrons of target atoms. Another type of interaction in
which the projectile electron can lose its kinetic energy is an interaction with the nucleus
of a target atom. In this type of interaction the kinetic energy of the projectile electron is
converted into electromagnetic energy.
A projectile electron that completely avoids the orbital electrons as it passes through a
target atom may come sufficiently close to the nucleus of the atom to come under its
influence. Because the electron is negatively charged and the nucleus is positively
charged, there is an electrostatic force of attraction between them. The closer the
projectile electron gets to the nucleus, the more it is influenced by the electrostatic field
of the nucleus. This field is very strong because the nucleus contains many protons and
the distance between the nucleus and the projectile electron is very small. As the
projectile electron passes by the nucleus, it slows down, changes its course, and leaves
with reduced kinetic energy in a different direction. These types of X-rays are called
Bremsstrahlung X-rays. Bremsstrahlung is a German word for slowing down or braking.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17. No feedback of generated KV, mA/
open loop
High Skin Dose
Inferior image quality
21. DC
AC
DC
AC
DC
AC
Line Input
EMI Filter
Inverter High Voltage
Transformer
400 V » UDC = 566 V
IGBT: fres
= 30 - 100 kHz
U T
= 40 - 150 kV
I T
= 0,1 - 1000 mA
P Puls = 4 W - 100 kW
P 60s £ 40 kW
P 10min £ 10 kW
U Tube
ITube
IF
Tube Rotating Anode
Control
fan = 4 - 300 Hz IGBT
S = 10 - 20 kVA
PWM
fres
= 20 - 100 kHz
PH = 100 - 150 W
IGBT
3 »
UDC
77. A Crossed grid has two grids sandwiched together
with the result that the strips are usually both
parallel to and at right angles to the long
dimension of the grid.
78. A focused grid is one in which the lead strips
are tilted progressively as they move away
from center. Lines through each of these strips
would converge at a point known as the grid
focus.
79.
80.
81.
82. Grid Primary Transmission
The useful X-Rays which pass straight from
the X-Ray tube to the film are known as
Primary transmission is basically the
percentage of primary X-Rays which pass
through the grid and hit the film, and is thus
measured by using the same apparatus with
and without the grid in place.
83.
84.
85.
86.
87.
88.
89. Grid cutoff is an undesirable absorption of
primary x-ray beams by grid strips, which
prevents the useful x-rays from reaching the
image receptor. It is caused by improper
grid positioning and most often occurs with
parallel grids.
90.
91.
92.
93. The quantity of scattered radiation in an x-ray beam reaching a
receptor can be reduced by separating the patient's body and
receptor surface, as shown below. This separation is known as
an air gap. Scattered radiation leaving a patient's body is more
divergent than the primary x-ray beam. Therefore, scattered
radiation spreads out of the primary beam area. The reduction of
scattered radiation in proportion to primary radiation increases
with air-gap distance. Several factors must be considered when
using this method of scatter reduction. Patient exposure is increased
because of the inverse-square effect. The use of an air gap
introduces magnification. Therefore, a larger receptor size is
required to obtain the same patient area coverage. If the air gap is
obtained by increasing the tube-to-receptor distance, the x-ray
equipment must be operated at a higher output to obtain adequate
receptor exposure.
94.
95. A bucky is typically used for table or wall
mounted x-raysystems and holds the x-
ray cassette and grid. A bucky, is a device
found underneath the exam table, a drawer like
device that the cassette and grid is slid into
before shooting x-ray.
113. Oil in x-ray tube and HV Transformer
for cooling and Insulation
That is stable at high temperatures and has
excellent electrical insulating properties Its
functions are
To insulate,
suppress corona ,
Supress arcing, and to serve as a coolant.
116. An AEC system uses a physically thin
radiation
An AEC system uses a physically thin radiation ionization
detector "AEC detector" which is positioned between the
patient being x-rayed and the x-ray film cassette. X-rays
passing through the patient also pass through this "AEC
detector" before they strike the x-ray film.
A weak ionization signal from the AEC detector is
integrated as a ramp shaped voltage waveform. This ramp
signal rises until it matches a pre-set threshold. At this
point the x-ray exposure is terminated. AEC devices are
calibrated to ensure that similar exams have linearity in
exam densities. This is due to the fact that a milliamperage
station is no longer selected and instead relies upon the
ionization within the selected chambers