PHYSICS AND CHEMISTRY OF RADIATION ABSORPTION 1.pptxDr Monica P
Radiobiology is the study of the action of Ionizing radiations on the living things.
The absorption of energy from the radiation in biologic material leads to either of the following two processes: EXCITATION, IONIZATION
Interactions of X-ray & matter & Attenuation - Dr. Sayak DattaSayakDatta
Slideshow on Radio-physics covering different interactions between X-ray and matter along with Attenuation. It includes Photo-electric effect, Compton scatter, Coherent scatter, Attenuation of Monochromatic & Polychromatic radiation, Diagnostic Xray applications, Scatter radiations.
PHYSICS AND CHEMISTRY OF RADIATION ABSORPTION 1.pptxDr Monica P
Radiobiology is the study of the action of Ionizing radiations on the living things.
The absorption of energy from the radiation in biologic material leads to either of the following two processes: EXCITATION, IONIZATION
Interactions of X-ray & matter & Attenuation - Dr. Sayak DattaSayakDatta
Slideshow on Radio-physics covering different interactions between X-ray and matter along with Attenuation. It includes Photo-electric effect, Compton scatter, Coherent scatter, Attenuation of Monochromatic & Polychromatic radiation, Diagnostic Xray applications, Scatter radiations.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
2. Content :
1-Some definition
- CT.
-radiology .
2-Introduction .
3- Interaction of radiation with matter .
4- X-ray production and X-ray tube.
3. CT device
CT:
is the device that used in radiology .
Radiology:
A branch of medicine concerned with the use of
radiant energy as x-rays or radioactive material in the
diagnosis and treatment of disease .
4. INTRODUCTION
-CT developed into a versatile 3D whole the body
imaging modality for oncology , cardiology and
vascular radiology this when was CT introduced
but now is use for radiology planning and CT
scanner can integrated with a PET scanner .
Purpose :
-Measure x-ray transmission through patient.
5. The essential physics of medical
image
-Radiation may be ionizing radiation or non-ionizing
radiation
Ionizing radiation may be :
1—Directly ionizing radiation (charged particles):
electrons, protons, a particles and heavy ions.
2—Indirectly ionizing radiation
(neutral particles):
photons (X rays and g rays), neutrons.
6. photon interactions with matter :
During the interaction the photon may;
1-completely disappear (photoelectric effect, pair
production, triplet production).
2-scattered coherently (coherent scattering)
or incoherently (Compton effect).
7. 1_Photoelectric effect:
A photon interact with an atom and ejects one of the
orbital electrons from the atom , the incident photon
energy is transferred to the atomic electron. The kinetic
energy of the ejected photoelectron(Ee) is equal to the
incident photon energy (Eo) minus the binding energy of
the orbital electron (Eb)
Ee = E0 – Eb
8. After the electron has been ejected from the
atom, a vacancy is created in the shell (atom in
excited state ) .this vacancy can be filled by an
outer orbital electron with the emission of the
characteristic x-rays .
9. 2-Coherent (Rayleigh) scattering:
An electromagnetic wave passing near the electron and
setting it into oscillation ,this electron radiates the
energy at the same frequency as the incident
electromagnetic wave . thse scatter x-ray that
have the same wavelength as the incident
beam .
10. 3-Compton Effect (incoherent
scattering):
Photon interaction with a free and stationary’ orbital
electron. the electron receives some energy from the
photon and emitted at an angle ϴ.
“The term of free electron mean that the binding
energy of the electron is much less than the energy of
bombarding photon .”
11. 4-Pair and triplet production
In pair production, an X- or gamma ray interacts with
the electric field of the nucleus of an atom. The
photon's energy is transformed into an electron-
positron pair. The electron and positron lose their
kinetic energy via excitation and ionization. when the
positron comes to rest, it interacts with a negatively
charged electron, resulting in the formation of two
oppositely directed 0.511( The rest mass energy) MeV
annihilation photons..
12.
13. Beam attenuation
The intensity Ix of a narrow monoenergetic
photon beam, attenuated by an attenuator
of thickness x, is given as:
Ix = Io e m x
where I0 is the original intensity of the
unattenuated
beam
m is the linear attenuation coefficient.
14. X-ray Production, X-ray
Tubes
-Superficial and orthovoltage X rays used in
radiotherapy are produced with X ray
machines.
The main components of a radio-
therapeutic X ray machine are:
an X ray tube, a ceiling or floor mount for the
X ray tube, a target cooling system, a
control
console, and an X ray power
generator
15.
16. -The electrons producing the X ray
beams in the X ray tube originate in
the heated filament (cathode) and
are accelerated in a vacuum towards
the target (anode) by a constant
potential electrostatic field supplied
by the X ray generator
17. -With X ray tubes, the patient dose is
delivered using a timer and the
treatment time must incorporate the
shutter correction time which accounts
for the time required for the power
supply components to attain the steady
state operating conditions.
18. -The X ray tube current is controlled by a
hot filament emission of electrons, which,
in turn, is controlled by the filament
temperature (thermionic emission).
-For a given filament temperature the X
ray tube current increases with the tube
(anode) voltage.
19. X-RAY TUBE INSER
:
-The x-ray tube insert contains the cathode,
anode, rotor assembly, and support structures
sealed in a glass or metal enclosure under a
high vacuum.
-X-rays are emitted in all directions from the
focal spot however, the x-rays that emerge
through the tube port constitute the useful
beam.
20. X-Ray Tube Housing
-The x-ray tube housing supports, insulates,
and protects the x-ray tube insert from the
environment.
-x-ray tube housing contains a bellows to allow
for oil expansion as it absorbs heat during
operation.
-Lead shielding inside the housing attenuates
the x-rays that are emitted in all directions, and
of course there is a hole in the shielding at the
x-ray tube port.
21. Special X-Ray Tube Designs
-Grid-biased tubes have a focusing cup that is
electrically isolated from the cathode filament .
-When the bias voltage is large, the resulting
electric field lines shut off the tube current.
- The grid-biased tube is used in applications
such as pulsed fluoroscopy and radiography.
-rays that penetrate this lead shielding, and
therefore it has a high effective energy.
22. presented by :
Rania saeed
Omneya kamal el deen awadein
Aya glal ramdan
Lamiaa ali
Mariam essam