Biostatistics is the application of statistics to biological and medical problems. Francis Galton is considered the father of biostatistics, developing concepts like correlation and using statistical tools and surveys to study human populations. Biostatistics has various applications in fields like physiology, pharmacology, and medicine. It is used to determine normal vs abnormal values in populations, compare variables between groups, assess drug efficacy and safety, identify disease signs and symptoms, and help determine optimal treatments.