This document discusses factors related to determining sample size for research studies. It defines key terms like sample size, population and importance of sample size. The selection of sample size involves planning the study, specifying parameters, choosing an effect size, and computing the sample size based on those factors. Sample size is influenced by expected effect size, study power, heterogeneity, error risk, and other variables. Dropouts from the sample during a study also impact sample size calculations. Proper determination of sample size is important for obtaining meaningful results and conducting ethical research.