SlideShare a Scribd company logo
Subtitle
BIOSAFETY GUIDELINES
 Policy proposed or adopted by the Government to avoid the risks
of GEOs on environment and public health.
What is biosafety guidelines?
 Regulating rDNA research with organisms that have least or no
adverse effect.
 Minimizing the possibilities of occasional release of GEOs from the
laboratory
 Banning the release of GEOs if they are supposed to be causing
potential risks in the environment
Aim of biosafety guidelines
 In India, DBT has proposed “The recombinant DNA safety
guidelines” in 1983 and amended in 1990.
 These guidelines deals with a set of rules for production, use,
import, export and storage of hazardous organisms.
The rDNA Biosafety Guidelines Of India
 Institutional biosafety committee (IBSC)- controls research
activities at institutional level.
 Review committee on genetic manipulation(RCGM)- reviews
special situations where research with hazardous organisms in
laboratory and grants permission to do that research.
 Genetic engineering approval committee(GEAC)- approves the
GEOs for large scale production and use in India.
In India, the rDNA guidelines has been implanted
through three committees
 Toxin gene cloning
 Cloning of genes for vaccine production
 Cloning of mosquito and tick DNA
 Cloning of antibiotics resistance genes
 Cloning of oncogenes
 Experiments with infectious animal and plant viruses
 Transgenesis experiment in animal cell cultures
 Transfer of toxicity genes into plants
 Gene therapy for hereditary diseases
To perform certain gene manipulation experiments,theworkers
need to acquire permission of review committee and approval
committee before commencement
 The term "Containment" is used in describing the safe methods
for managing infectious agents in the laboratory environment
where they are being handled or maintained.
CONTAINMENTS
 To reduce exposure of laboratory workers, other persons, and
outside environment to potentially
Purpose of containments
 Laboratory Practice and Technique
 Safety Equipment(primary barriers)
 Design Facility(Secondary Barrier)
Elements of containments
 Physical containment
 Biological containment
types of containments
 The physical methods being adopted inside the laboratories to
prevent escaping the GEOs to the environment
 It works on the principal of physical barriers
 It helps to keep the dirt in the laboratory itself
Physical containment
 Air filtration
 Sterilization lights
 Waste disposal
 Protective handling
The physical containment include
 The biological principles used in the laboratories to prevent the
escape of GEOs or microbes
 Biological containment makes the organisms unable to survive in
the outside environment
Biological containment
 The rDNA biosafety guidelines are implemented for the
government of India by four committee
 Recombinant DNA advisory committee (RDAC)
 Institutional biosafety committee (IBSC)
 Review committee on genetic manipulation (RCGM)
 Genetic engineering approval committee (GEAC)
Implementation of biosafety guidelines
 Organized by the Department of
Biotechnology (DBT) under the
Ministry of science and technology
 It provides regulatory control to the
implementation committees
Recombinant DNA advisory committee (RDAC)
 These meeting helps to
 Evolve long term policy for R/D in rDNA research
 Formulate suitable safety guidelines
 Train the research and technicians about the hazards and risks of
rDNA research techniques
The RDAC has been arranging meeting once in six
months or sooner to discuss about the standards of
safety regulations
 This is a small committee established by
every institution engaged in rDNA
research and the related production
activities
 It monitors rDNA research activities at the
institutional level
 This committee is formed of head of
institution, 3or more scientists, a medical
officer and one DBT nominated person
Institutional biosafety committee (IBSC)
 Sends report to RCGM regarding observance of safety guidelines
on accidents risks and on deviations if any
 Reviews the requirements of guidelines for safety new projects
 Allows some person to take training on biosafety in research
activities
 Takes emergency plans in urgent situations
 Attempts to provide medical care to persons working in the
laboratory
Role of IBSC
 The RCGM is functioning under DBT
 It is formed of
 Department of biotechnology (DBT)
 Indian council of medical research (ICMR)
 Indian council of agricultural research
(ICAR)
 Council of scientific and industrial research
(CSIR)
 Department of science and technology
(DST)
Review committee on genetic manipulation (RCGM)
 Establishes the procedural guidance manual for regulatory process
with GEOs
 It reviews the risk potentials of GEOs in the laboratory and field
experiments
 It decides which containment have to be followed for experiments
with risky hazardous microbes
 It advices custom authorities on import of GEOs and other
biological materials from other nations
 It provides advice on IPR and patents
RCGM functions
 It assists the Bureau of India standards (BIS) to evolve standards
of products coming from rDNA technology
 The monitoring group of RCGM visit frequently to laboratories
where rDNA works are going on and inspects safety conditions in
those lab
 This is a higher level committee working
under the Department of Environment and
Forests.
 It has full power to permit
 Large scale use of genetically
engineered organisms
 rDNA products
 R/D of rDNA technology
 Industrial production of rDNA products
 Release of GEOS in environment and
field use
GENETIC ENGINEERING APPROVAL
COMMITTEE (GEAC)
 Import, export, transport,production and sale of GEOs and other
organisms
 Release of GEOs from the laboratories to environment
 Large scale culture and use of GEOs and microbes in industries
 Use of GEOs in field application and experimental trials
 Monitoring the risks and accidents due to GEOs
The GEAC gives approval for
Mechanism of implementation
Biosafety guidelines
Biosafety guidelines

More Related Content

What's hot

Gene transformation methods
Gene transformation methodsGene transformation methods
Recombinant dna guidelines(1990)
Recombinant dna guidelines(1990)Recombinant dna guidelines(1990)
Recombinant dna guidelines(1990)
Vipin Shukla
 
Bioethics and Biosafety
Bioethics and BiosafetyBioethics and Biosafety
Bioethics and Biosafety
APCER Life Sciences
 
Genomic library
Genomic libraryGenomic library
Genomic library
Chinnu S Kumar
 
Isolation of industrial microorganisms
Isolation of industrial microorganismsIsolation of industrial microorganisms
Isolation of industrial microorganisms
NithyaNandapal
 
Linker, Adaptor, Homopolymeric Tailing & Terminal Transferase
Linker, Adaptor, Homopolymeric Tailing & Terminal TransferaseLinker, Adaptor, Homopolymeric Tailing & Terminal Transferase
Linker, Adaptor, Homopolymeric Tailing & Terminal Transferase
Utsa Roy
 
SAGE (Serial analysis of Gene Expression)
SAGE (Serial analysis of Gene Expression)SAGE (Serial analysis of Gene Expression)
SAGE (Serial analysis of Gene Expression)
talhakhat
 
Gene cloning strategies
Gene cloning strategiesGene cloning strategies
Gene cloning strategies
neelotpal31
 
Gen bank databases
Gen bank databasesGen bank databases
Gen bank databases
Hafiz Muhammad Zeeshan Raza
 
M13 phage
M13 phageM13 phage
M13 phage
PrakashL12
 
Transgenic mice
Transgenic miceTransgenic mice
Transgenic mice
KAUSHAL SAHU
 
Herbicide resistance
Herbicide resistanceHerbicide resistance
Herbicide resistance
joshnamalempati
 
Biosafety
BiosafetyBiosafety
Biosafety
ManojKumar5984
 
Biosafety
BiosafetyBiosafety
Biosafety
sijiskariah
 
Strain development techniques of industrially important microorganisms
Strain development techniques of industrially important microorganismsStrain development techniques of industrially important microorganisms
Strain development techniques of industrially important microorganisms
Microbiology
 
Primary culture and cell line
Primary culture and cell linePrimary culture and cell line
Primary culture and cell line
KAUSHAL SAHU
 
Shuttle vector - a plasmid vector used in rDNA technology.
Shuttle vector - a plasmid vector used in rDNA technology. Shuttle vector - a plasmid vector used in rDNA technology.
Shuttle vector - a plasmid vector used in rDNA technology.
neeru02
 
reporter gene
reporter genereporter gene
reporter gene
Ritasree Sarma
 
Genome annotation
Genome annotationGenome annotation
Genome annotation
Shifa Ansari
 
Ethical issues in biotechnology
Ethical issues in biotechnologyEthical issues in biotechnology
Ethical issues in biotechnology
Bahauddin Zakariya University lahore
 

What's hot (20)

Gene transformation methods
Gene transformation methodsGene transformation methods
Gene transformation methods
 
Recombinant dna guidelines(1990)
Recombinant dna guidelines(1990)Recombinant dna guidelines(1990)
Recombinant dna guidelines(1990)
 
Bioethics and Biosafety
Bioethics and BiosafetyBioethics and Biosafety
Bioethics and Biosafety
 
Genomic library
Genomic libraryGenomic library
Genomic library
 
Isolation of industrial microorganisms
Isolation of industrial microorganismsIsolation of industrial microorganisms
Isolation of industrial microorganisms
 
Linker, Adaptor, Homopolymeric Tailing & Terminal Transferase
Linker, Adaptor, Homopolymeric Tailing & Terminal TransferaseLinker, Adaptor, Homopolymeric Tailing & Terminal Transferase
Linker, Adaptor, Homopolymeric Tailing & Terminal Transferase
 
SAGE (Serial analysis of Gene Expression)
SAGE (Serial analysis of Gene Expression)SAGE (Serial analysis of Gene Expression)
SAGE (Serial analysis of Gene Expression)
 
Gene cloning strategies
Gene cloning strategiesGene cloning strategies
Gene cloning strategies
 
Gen bank databases
Gen bank databasesGen bank databases
Gen bank databases
 
M13 phage
M13 phageM13 phage
M13 phage
 
Transgenic mice
Transgenic miceTransgenic mice
Transgenic mice
 
Herbicide resistance
Herbicide resistanceHerbicide resistance
Herbicide resistance
 
Biosafety
BiosafetyBiosafety
Biosafety
 
Biosafety
BiosafetyBiosafety
Biosafety
 
Strain development techniques of industrially important microorganisms
Strain development techniques of industrially important microorganismsStrain development techniques of industrially important microorganisms
Strain development techniques of industrially important microorganisms
 
Primary culture and cell line
Primary culture and cell linePrimary culture and cell line
Primary culture and cell line
 
Shuttle vector - a plasmid vector used in rDNA technology.
Shuttle vector - a plasmid vector used in rDNA technology. Shuttle vector - a plasmid vector used in rDNA technology.
Shuttle vector - a plasmid vector used in rDNA technology.
 
reporter gene
reporter genereporter gene
reporter gene
 
Genome annotation
Genome annotationGenome annotation
Genome annotation
 
Ethical issues in biotechnology
Ethical issues in biotechnologyEthical issues in biotechnology
Ethical issues in biotechnology
 

Viewers also liked

Embryo culture
Embryo cultureEmbryo culture
Embryo culture
Aakilasahul3010
 
Biosafety Regulations of Asian Countries 2013
Biosafety Regulations of Asian Countries 2013Biosafety Regulations of Asian Countries 2013
Biosafety Regulations of Asian Countries 2013
Asian Food Regulation Information Service
 
Bt cotton benefits, costs, and impacts
Bt cotton benefits, costs, and impactsBt cotton benefits, costs, and impacts
Bt cotton benefits, costs, and impacts
Abdallah Albeltagy
 
Cpoe bibliography
Cpoe bibliographyCpoe bibliography
Cpoe bibliography
NIH
 
Biosafety level and biosafety cabinets
Biosafety level and biosafety cabinetsBiosafety level and biosafety cabinets
Biosafety level and biosafety cabinets
Techef In
 
10 traditional knowledge
10 traditional knowledge10 traditional knowledge
10 traditional knowledge
RST ECOENERGY PVT. LTD.
 
Protection of Traditional Knowledge
Protection of Traditional KnowledgeProtection of Traditional Knowledge
Protection of Traditional Knowledge
patent_unitedipr
 
Biosafety
Biosafety Biosafety
Biosafety
Malathi Murugesan
 
World health organisation
World health organisationWorld health organisation
World health organisation
Sujata Mohapatra
 

Viewers also liked (9)

Embryo culture
Embryo cultureEmbryo culture
Embryo culture
 
Biosafety Regulations of Asian Countries 2013
Biosafety Regulations of Asian Countries 2013Biosafety Regulations of Asian Countries 2013
Biosafety Regulations of Asian Countries 2013
 
Bt cotton benefits, costs, and impacts
Bt cotton benefits, costs, and impactsBt cotton benefits, costs, and impacts
Bt cotton benefits, costs, and impacts
 
Cpoe bibliography
Cpoe bibliographyCpoe bibliography
Cpoe bibliography
 
Biosafety level and biosafety cabinets
Biosafety level and biosafety cabinetsBiosafety level and biosafety cabinets
Biosafety level and biosafety cabinets
 
10 traditional knowledge
10 traditional knowledge10 traditional knowledge
10 traditional knowledge
 
Protection of Traditional Knowledge
Protection of Traditional KnowledgeProtection of Traditional Knowledge
Protection of Traditional Knowledge
 
Biosafety
Biosafety Biosafety
Biosafety
 
World health organisation
World health organisationWorld health organisation
World health organisation
 

Similar to Biosafety guidelines

BIOSAFETY.pdf
BIOSAFETY.pdfBIOSAFETY.pdf
BIOSAFETY.pdf
ciprofloxacinoxytoci
 
Biosafety_Guidelines (1).pdf
Biosafety_Guidelines (1).pdfBiosafety_Guidelines (1).pdf
Biosafety_Guidelines (1).pdf
KumarKDevi
 
Biosafety level
Biosafety levelBiosafety level
Biosafety level
shivanki verma
 
gmc biosafetypptx.pptx
gmc biosafetypptx.pptxgmc biosafetypptx.pptx
gmc biosafetypptx.pptx
Sheetal Vishwakarma
 
Genetic Modified Organism Regulation in India
Genetic Modified Organism  Regulation in IndiaGenetic Modified Organism  Regulation in India
Genetic Modified Organism Regulation in India
MeehirMerai
 
transgenic crops and their regulatory system
transgenic crops and their regulatory systemtransgenic crops and their regulatory system
transgenic crops and their regulatory system
Guru P N
 
Developments on Biosafety Regulatory Regime in Bangladesh 2013
Developments on Biosafety Regulatory Regime in Bangladesh 2013Developments on Biosafety Regulatory Regime in Bangladesh 2013
Developments on Biosafety Regulatory Regime in Bangladesh 2013
Asian Food Regulation Information Service
 
06 overview of biosafety activities of moefcc
06 overview of biosafety activities of moefcc06 overview of biosafety activities of moefcc
06 overview of biosafety activities of moefcc
Indranil Bhattacharjee
 
Regulatory aspects associated to genome editing in India
Regulatory aspects associated to genome editing in IndiaRegulatory aspects associated to genome editing in India
Regulatory aspects associated to genome editing in India
OECD Environment
 
intelectual property rights on transgenics
intelectual property rights on transgenicsintelectual property rights on transgenics
intelectual property rights on transgenics
Anilkumar C
 
David Glass BIO World Congress Synthetic Biology Regulation july 2015
David Glass BIO World Congress Synthetic Biology Regulation july 2015David Glass BIO World Congress Synthetic Biology Regulation july 2015
David Glass BIO World Congress Synthetic Biology Regulation july 2015
David Glass
 
Safety considerations and guidelines veterinary microbiology laboratory
Safety considerations and guidelines veterinary microbiology laboratorySafety considerations and guidelines veterinary microbiology laboratory
Safety considerations and guidelines veterinary microbiology laboratory
Ravi Kant Agrawal
 
Geac
GeacGeac
radiation regulatory bodies. ( international + indian )
radiation regulatory bodies. ( international + indian )radiation regulatory bodies. ( international + indian )
radiation regulatory bodies. ( international + indian )
akshayonslideshar
 
National and International Regulatory Framework for GM Crops_2015
National and International Regulatory Framework for GM Crops_2015National and International Regulatory Framework for GM Crops_2015
National and International Regulatory Framework for GM Crops_2015
Asian Food Regulation Information Service
 
rdna guidelines
rdna guidelinesrdna guidelines
rdna guidelines
Shekhar Tidke
 
BIOSAFETY AND INDIAN ETHICS (DRA)
BIOSAFETY AND INDIAN ETHICS (DRA)BIOSAFETY AND INDIAN ETHICS (DRA)
BIOSAFETY AND INDIAN ETHICS (DRA)
APCER Life Sciences
 
Biosafety lecture 1[1]
Biosafety lecture 1[1]Biosafety lecture 1[1]
Biosafety lecture 1[1]
Jamilu Yarima
 
Indian Biosafety Framework.pptx
Indian Biosafety Framework.pptxIndian Biosafety Framework.pptx
Indian Biosafety Framework.pptx
NSaiKishore1
 
04 control of spills and mechanism of implementation of biosafety guidelines
04 control of spills and mechanism of implementation of biosafety guidelines04 control of spills and mechanism of implementation of biosafety guidelines
04 control of spills and mechanism of implementation of biosafety guidelines
Indranil Bhattacharjee
 

Similar to Biosafety guidelines (20)

BIOSAFETY.pdf
BIOSAFETY.pdfBIOSAFETY.pdf
BIOSAFETY.pdf
 
Biosafety_Guidelines (1).pdf
Biosafety_Guidelines (1).pdfBiosafety_Guidelines (1).pdf
Biosafety_Guidelines (1).pdf
 
Biosafety level
Biosafety levelBiosafety level
Biosafety level
 
gmc biosafetypptx.pptx
gmc biosafetypptx.pptxgmc biosafetypptx.pptx
gmc biosafetypptx.pptx
 
Genetic Modified Organism Regulation in India
Genetic Modified Organism  Regulation in IndiaGenetic Modified Organism  Regulation in India
Genetic Modified Organism Regulation in India
 
transgenic crops and their regulatory system
transgenic crops and their regulatory systemtransgenic crops and their regulatory system
transgenic crops and their regulatory system
 
Developments on Biosafety Regulatory Regime in Bangladesh 2013
Developments on Biosafety Regulatory Regime in Bangladesh 2013Developments on Biosafety Regulatory Regime in Bangladesh 2013
Developments on Biosafety Regulatory Regime in Bangladesh 2013
 
06 overview of biosafety activities of moefcc
06 overview of biosafety activities of moefcc06 overview of biosafety activities of moefcc
06 overview of biosafety activities of moefcc
 
Regulatory aspects associated to genome editing in India
Regulatory aspects associated to genome editing in IndiaRegulatory aspects associated to genome editing in India
Regulatory aspects associated to genome editing in India
 
intelectual property rights on transgenics
intelectual property rights on transgenicsintelectual property rights on transgenics
intelectual property rights on transgenics
 
David Glass BIO World Congress Synthetic Biology Regulation july 2015
David Glass BIO World Congress Synthetic Biology Regulation july 2015David Glass BIO World Congress Synthetic Biology Regulation july 2015
David Glass BIO World Congress Synthetic Biology Regulation july 2015
 
Safety considerations and guidelines veterinary microbiology laboratory
Safety considerations and guidelines veterinary microbiology laboratorySafety considerations and guidelines veterinary microbiology laboratory
Safety considerations and guidelines veterinary microbiology laboratory
 
Geac
GeacGeac
Geac
 
radiation regulatory bodies. ( international + indian )
radiation regulatory bodies. ( international + indian )radiation regulatory bodies. ( international + indian )
radiation regulatory bodies. ( international + indian )
 
National and International Regulatory Framework for GM Crops_2015
National and International Regulatory Framework for GM Crops_2015National and International Regulatory Framework for GM Crops_2015
National and International Regulatory Framework for GM Crops_2015
 
rdna guidelines
rdna guidelinesrdna guidelines
rdna guidelines
 
BIOSAFETY AND INDIAN ETHICS (DRA)
BIOSAFETY AND INDIAN ETHICS (DRA)BIOSAFETY AND INDIAN ETHICS (DRA)
BIOSAFETY AND INDIAN ETHICS (DRA)
 
Biosafety lecture 1[1]
Biosafety lecture 1[1]Biosafety lecture 1[1]
Biosafety lecture 1[1]
 
Indian Biosafety Framework.pptx
Indian Biosafety Framework.pptxIndian Biosafety Framework.pptx
Indian Biosafety Framework.pptx
 
04 control of spills and mechanism of implementation of biosafety guidelines
04 control of spills and mechanism of implementation of biosafety guidelines04 control of spills and mechanism of implementation of biosafety guidelines
04 control of spills and mechanism of implementation of biosafety guidelines
 

Recently uploaded

Adjusted NuGOweek 2024 Ghent programme flyer
Adjusted NuGOweek 2024 Ghent programme flyerAdjusted NuGOweek 2024 Ghent programme flyer
Adjusted NuGOweek 2024 Ghent programme flyer
pablovgd
 
How Does TaskTrain Integrate Workflow and Project Management Efficiently.pdf
How Does TaskTrain Integrate Workflow and Project Management Efficiently.pdfHow Does TaskTrain Integrate Workflow and Project Management Efficiently.pdf
How Does TaskTrain Integrate Workflow and Project Management Efficiently.pdf
Task Train
 
MCQ in Electrostatics. for class XII pptx
MCQ in Electrostatics. for class XII  pptxMCQ in Electrostatics. for class XII  pptx
MCQ in Electrostatics. for class XII pptx
ArunachalamM22
 
Analytical methods for blue residues characterization - Oana Crina Bujor
Analytical methods for blue residues characterization - Oana Crina BujorAnalytical methods for blue residues characterization - Oana Crina Bujor
Analytical methods for blue residues characterization - Oana Crina Bujor
Faculty of Applied Chemistry and Materials Science
 
Introduction to Space (Our Solar System)
Introduction to Space (Our Solar System)Introduction to Space (Our Solar System)
Introduction to Space (Our Solar System)
vanshgarg8002
 
THE ESSENCE OF CHANGE CHAPTER ,energy,conversion,life is easy,laws of physics
THE ESSENCE OF CHANGE CHAPTER ,energy,conversion,life is easy,laws of physicsTHE ESSENCE OF CHANGE CHAPTER ,energy,conversion,life is easy,laws of physics
THE ESSENCE OF CHANGE CHAPTER ,energy,conversion,life is easy,laws of physics
Dr. sreeremya S
 
Celebrity Girls Call Navi Mumbai 🎈🔥9920725232 🔥💋🎈 Provide Best And Top Girl S...
Celebrity Girls Call Navi Mumbai 🎈🔥9920725232 🔥💋🎈 Provide Best And Top Girl S...Celebrity Girls Call Navi Mumbai 🎈🔥9920725232 🔥💋🎈 Provide Best And Top Girl S...
Celebrity Girls Call Navi Mumbai 🎈🔥9920725232 🔥💋🎈 Provide Best And Top Girl S...
bellared2
 
MARIGREEN PROJECT - overview, Oana Cristina Pârvulescu
MARIGREEN PROJECT - overview, Oana Cristina PârvulescuMARIGREEN PROJECT - overview, Oana Cristina Pârvulescu
MARIGREEN PROJECT - overview, Oana Cristina Pârvulescu
Faculty of Applied Chemistry and Materials Science
 
Traditional, current and future use of fish and seaweed for fertilisation - ...
Traditional, current and future use of fish and seaweed for fertilisation -  ...Traditional, current and future use of fish and seaweed for fertilisation -  ...
Traditional, current and future use of fish and seaweed for fertilisation - ...
Faculty of Applied Chemistry and Materials Science
 
Plant Kingdom BioHack class 11 neet ....
Plant Kingdom BioHack class 11 neet ....Plant Kingdom BioHack class 11 neet ....
Plant Kingdom BioHack class 11 neet ....
anushkakharat13
 
Gametogenesis: Male gametes Formation Process / Spermatogenesis .pdf
Gametogenesis: Male gametes Formation Process / Spermatogenesis .pdfGametogenesis: Male gametes Formation Process / Spermatogenesis .pdf
Gametogenesis: Male gametes Formation Process / Spermatogenesis .pdf
SELF-EXPLANATORY
 
Potential of Marine renewable and Non renewable energy.pptx
Potential of Marine renewable and Non renewable energy.pptxPotential of Marine renewable and Non renewable energy.pptx
Potential of Marine renewable and Non renewable energy.pptx
J. Bovas Joel BFSc
 
Pancreas_functional anatomy_enzymes.pptx
Pancreas_functional anatomy_enzymes.pptxPancreas_functional anatomy_enzymes.pptx
Pancreas_functional anatomy_enzymes.pptx
muralinath2
 
Rapid pulse drying of marine biomasses - Sigurd Sannan
Rapid pulse drying of marine biomasses - Sigurd SannanRapid pulse drying of marine biomasses - Sigurd Sannan
Rapid pulse drying of marine biomasses - Sigurd Sannan
Faculty of Applied Chemistry and Materials Science
 
Direct instructions, towards hundred fold yield,layering,budding,grafting,pla...
Direct instructions, towards hundred fold yield,layering,budding,grafting,pla...Direct instructions, towards hundred fold yield,layering,budding,grafting,pla...
Direct instructions, towards hundred fold yield,layering,budding,grafting,pla...
Dr. sreeremya S
 
SCIENCEgfvhvhvkjkbbjjbbjvhvhvhvjkvjvjvjj.pptx
SCIENCEgfvhvhvkjkbbjjbbjvhvhvhvjkvjvjvjj.pptxSCIENCEgfvhvhvkjkbbjjbbjvhvhvhvjkvjvjvjj.pptx
SCIENCEgfvhvhvkjkbbjjbbjvhvhvhvjkvjvjvjj.pptx
WALTONMARBRUCAL
 
AlgaeBrew project - Unlocking the potential of microalgae for the valorisatio...
AlgaeBrew project - Unlocking the potential of microalgae for the valorisatio...AlgaeBrew project - Unlocking the potential of microalgae for the valorisatio...
AlgaeBrew project - Unlocking the potential of microalgae for the valorisatio...
Faculty of Applied Chemistry and Materials Science
 
ellipticytescausesprognosistreatment-240622051139-23d50b05.pptx
ellipticytescausesprognosistreatment-240622051139-23d50b05.pptxellipticytescausesprognosistreatment-240622051139-23d50b05.pptx
ellipticytescausesprognosistreatment-240622051139-23d50b05.pptx
muralinath2
 
AN EMPIRE ACROSS THE THREE CONTINENTS.pptx
AN EMPIRE ACROSS THE THREE CONTINENTS.pptxAN EMPIRE ACROSS THE THREE CONTINENTS.pptx
AN EMPIRE ACROSS THE THREE CONTINENTS.pptx
kalpnayadav03021986
 
Detection of the elusive dangling OH ice features at ~2.7 μm in Chamaeleon I ...
Detection of the elusive dangling OH ice features at ~2.7 μm in Chamaeleon I ...Detection of the elusive dangling OH ice features at ~2.7 μm in Chamaeleon I ...
Detection of the elusive dangling OH ice features at ~2.7 μm in Chamaeleon I ...
Sérgio Sacani
 

Recently uploaded (20)

Adjusted NuGOweek 2024 Ghent programme flyer
Adjusted NuGOweek 2024 Ghent programme flyerAdjusted NuGOweek 2024 Ghent programme flyer
Adjusted NuGOweek 2024 Ghent programme flyer
 
How Does TaskTrain Integrate Workflow and Project Management Efficiently.pdf
How Does TaskTrain Integrate Workflow and Project Management Efficiently.pdfHow Does TaskTrain Integrate Workflow and Project Management Efficiently.pdf
How Does TaskTrain Integrate Workflow and Project Management Efficiently.pdf
 
MCQ in Electrostatics. for class XII pptx
MCQ in Electrostatics. for class XII  pptxMCQ in Electrostatics. for class XII  pptx
MCQ in Electrostatics. for class XII pptx
 
Analytical methods for blue residues characterization - Oana Crina Bujor
Analytical methods for blue residues characterization - Oana Crina BujorAnalytical methods for blue residues characterization - Oana Crina Bujor
Analytical methods for blue residues characterization - Oana Crina Bujor
 
Introduction to Space (Our Solar System)
Introduction to Space (Our Solar System)Introduction to Space (Our Solar System)
Introduction to Space (Our Solar System)
 
THE ESSENCE OF CHANGE CHAPTER ,energy,conversion,life is easy,laws of physics
THE ESSENCE OF CHANGE CHAPTER ,energy,conversion,life is easy,laws of physicsTHE ESSENCE OF CHANGE CHAPTER ,energy,conversion,life is easy,laws of physics
THE ESSENCE OF CHANGE CHAPTER ,energy,conversion,life is easy,laws of physics
 
Celebrity Girls Call Navi Mumbai 🎈🔥9920725232 🔥💋🎈 Provide Best And Top Girl S...
Celebrity Girls Call Navi Mumbai 🎈🔥9920725232 🔥💋🎈 Provide Best And Top Girl S...Celebrity Girls Call Navi Mumbai 🎈🔥9920725232 🔥💋🎈 Provide Best And Top Girl S...
Celebrity Girls Call Navi Mumbai 🎈🔥9920725232 🔥💋🎈 Provide Best And Top Girl S...
 
MARIGREEN PROJECT - overview, Oana Cristina Pârvulescu
MARIGREEN PROJECT - overview, Oana Cristina PârvulescuMARIGREEN PROJECT - overview, Oana Cristina Pârvulescu
MARIGREEN PROJECT - overview, Oana Cristina Pârvulescu
 
Traditional, current and future use of fish and seaweed for fertilisation - ...
Traditional, current and future use of fish and seaweed for fertilisation -  ...Traditional, current and future use of fish and seaweed for fertilisation -  ...
Traditional, current and future use of fish and seaweed for fertilisation - ...
 
Plant Kingdom BioHack class 11 neet ....
Plant Kingdom BioHack class 11 neet ....Plant Kingdom BioHack class 11 neet ....
Plant Kingdom BioHack class 11 neet ....
 
Gametogenesis: Male gametes Formation Process / Spermatogenesis .pdf
Gametogenesis: Male gametes Formation Process / Spermatogenesis .pdfGametogenesis: Male gametes Formation Process / Spermatogenesis .pdf
Gametogenesis: Male gametes Formation Process / Spermatogenesis .pdf
 
Potential of Marine renewable and Non renewable energy.pptx
Potential of Marine renewable and Non renewable energy.pptxPotential of Marine renewable and Non renewable energy.pptx
Potential of Marine renewable and Non renewable energy.pptx
 
Pancreas_functional anatomy_enzymes.pptx
Pancreas_functional anatomy_enzymes.pptxPancreas_functional anatomy_enzymes.pptx
Pancreas_functional anatomy_enzymes.pptx
 
Rapid pulse drying of marine biomasses - Sigurd Sannan
Rapid pulse drying of marine biomasses - Sigurd SannanRapid pulse drying of marine biomasses - Sigurd Sannan
Rapid pulse drying of marine biomasses - Sigurd Sannan
 
Direct instructions, towards hundred fold yield,layering,budding,grafting,pla...
Direct instructions, towards hundred fold yield,layering,budding,grafting,pla...Direct instructions, towards hundred fold yield,layering,budding,grafting,pla...
Direct instructions, towards hundred fold yield,layering,budding,grafting,pla...
 
SCIENCEgfvhvhvkjkbbjjbbjvhvhvhvjkvjvjvjj.pptx
SCIENCEgfvhvhvkjkbbjjbbjvhvhvhvjkvjvjvjj.pptxSCIENCEgfvhvhvkjkbbjjbbjvhvhvhvjkvjvjvjj.pptx
SCIENCEgfvhvhvkjkbbjjbbjvhvhvhvjkvjvjvjj.pptx
 
AlgaeBrew project - Unlocking the potential of microalgae for the valorisatio...
AlgaeBrew project - Unlocking the potential of microalgae for the valorisatio...AlgaeBrew project - Unlocking the potential of microalgae for the valorisatio...
AlgaeBrew project - Unlocking the potential of microalgae for the valorisatio...
 
ellipticytescausesprognosistreatment-240622051139-23d50b05.pptx
ellipticytescausesprognosistreatment-240622051139-23d50b05.pptxellipticytescausesprognosistreatment-240622051139-23d50b05.pptx
ellipticytescausesprognosistreatment-240622051139-23d50b05.pptx
 
AN EMPIRE ACROSS THE THREE CONTINENTS.pptx
AN EMPIRE ACROSS THE THREE CONTINENTS.pptxAN EMPIRE ACROSS THE THREE CONTINENTS.pptx
AN EMPIRE ACROSS THE THREE CONTINENTS.pptx
 
Detection of the elusive dangling OH ice features at ~2.7 μm in Chamaeleon I ...
Detection of the elusive dangling OH ice features at ~2.7 μm in Chamaeleon I ...Detection of the elusive dangling OH ice features at ~2.7 μm in Chamaeleon I ...
Detection of the elusive dangling OH ice features at ~2.7 μm in Chamaeleon I ...
 

Biosafety guidelines

  • 2.  Policy proposed or adopted by the Government to avoid the risks of GEOs on environment and public health. What is biosafety guidelines?
  • 3.  Regulating rDNA research with organisms that have least or no adverse effect.  Minimizing the possibilities of occasional release of GEOs from the laboratory  Banning the release of GEOs if they are supposed to be causing potential risks in the environment Aim of biosafety guidelines
  • 4.  In India, DBT has proposed “The recombinant DNA safety guidelines” in 1983 and amended in 1990.  These guidelines deals with a set of rules for production, use, import, export and storage of hazardous organisms. The rDNA Biosafety Guidelines Of India
  • 5.  Institutional biosafety committee (IBSC)- controls research activities at institutional level.  Review committee on genetic manipulation(RCGM)- reviews special situations where research with hazardous organisms in laboratory and grants permission to do that research.  Genetic engineering approval committee(GEAC)- approves the GEOs for large scale production and use in India. In India, the rDNA guidelines has been implanted through three committees
  • 6.  Toxin gene cloning  Cloning of genes for vaccine production  Cloning of mosquito and tick DNA  Cloning of antibiotics resistance genes  Cloning of oncogenes  Experiments with infectious animal and plant viruses  Transgenesis experiment in animal cell cultures  Transfer of toxicity genes into plants  Gene therapy for hereditary diseases To perform certain gene manipulation experiments,theworkers need to acquire permission of review committee and approval committee before commencement
  • 7.  The term "Containment" is used in describing the safe methods for managing infectious agents in the laboratory environment where they are being handled or maintained. CONTAINMENTS
  • 8.  To reduce exposure of laboratory workers, other persons, and outside environment to potentially Purpose of containments
  • 9.  Laboratory Practice and Technique  Safety Equipment(primary barriers)  Design Facility(Secondary Barrier) Elements of containments
  • 10.  Physical containment  Biological containment types of containments
  • 11.  The physical methods being adopted inside the laboratories to prevent escaping the GEOs to the environment  It works on the principal of physical barriers  It helps to keep the dirt in the laboratory itself Physical containment
  • 12.  Air filtration  Sterilization lights  Waste disposal  Protective handling The physical containment include
  • 13.  The biological principles used in the laboratories to prevent the escape of GEOs or microbes  Biological containment makes the organisms unable to survive in the outside environment Biological containment
  • 14.  The rDNA biosafety guidelines are implemented for the government of India by four committee  Recombinant DNA advisory committee (RDAC)  Institutional biosafety committee (IBSC)  Review committee on genetic manipulation (RCGM)  Genetic engineering approval committee (GEAC) Implementation of biosafety guidelines
  • 15.  Organized by the Department of Biotechnology (DBT) under the Ministry of science and technology  It provides regulatory control to the implementation committees Recombinant DNA advisory committee (RDAC)
  • 16.  These meeting helps to  Evolve long term policy for R/D in rDNA research  Formulate suitable safety guidelines  Train the research and technicians about the hazards and risks of rDNA research techniques The RDAC has been arranging meeting once in six months or sooner to discuss about the standards of safety regulations
  • 17.  This is a small committee established by every institution engaged in rDNA research and the related production activities  It monitors rDNA research activities at the institutional level  This committee is formed of head of institution, 3or more scientists, a medical officer and one DBT nominated person Institutional biosafety committee (IBSC)
  • 18.  Sends report to RCGM regarding observance of safety guidelines on accidents risks and on deviations if any  Reviews the requirements of guidelines for safety new projects  Allows some person to take training on biosafety in research activities  Takes emergency plans in urgent situations  Attempts to provide medical care to persons working in the laboratory Role of IBSC
  • 19.  The RCGM is functioning under DBT  It is formed of  Department of biotechnology (DBT)  Indian council of medical research (ICMR)  Indian council of agricultural research (ICAR)  Council of scientific and industrial research (CSIR)  Department of science and technology (DST) Review committee on genetic manipulation (RCGM)
  • 20.  Establishes the procedural guidance manual for regulatory process with GEOs  It reviews the risk potentials of GEOs in the laboratory and field experiments  It decides which containment have to be followed for experiments with risky hazardous microbes  It advices custom authorities on import of GEOs and other biological materials from other nations  It provides advice on IPR and patents RCGM functions
  • 21.  It assists the Bureau of India standards (BIS) to evolve standards of products coming from rDNA technology  The monitoring group of RCGM visit frequently to laboratories where rDNA works are going on and inspects safety conditions in those lab
  • 22.  This is a higher level committee working under the Department of Environment and Forests.  It has full power to permit  Large scale use of genetically engineered organisms  rDNA products  R/D of rDNA technology  Industrial production of rDNA products  Release of GEOS in environment and field use GENETIC ENGINEERING APPROVAL COMMITTEE (GEAC)
  • 23.  Import, export, transport,production and sale of GEOs and other organisms  Release of GEOs from the laboratories to environment  Large scale culture and use of GEOs and microbes in industries  Use of GEOs in field application and experimental trials  Monitoring the risks and accidents due to GEOs The GEAC gives approval for