This document discusses biomarkers for the diagnosis of Alzheimer's disease. It defines biomarkers and describes their use to detect, stage, and monitor Alzheimer's. Biomarkers found in cerebrospinal fluid include decreased Aβ42 and increased total tau and phosphorylated tau. Genetic markers like mutations in APP, PSEN1 and PSEN2 can cause early-onset Alzheimer's. Circulating miRNAs show potential as non-invasive blood biomarkers. Mass spectrometry is used to analyze various protein biomarkers but none have been satisfactory for diagnosis. Reliable blood biomarkers are still being sought to allow early, fast and non-invasive Alzheimer's diagnosis.