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Mohammad Mamdouh
B.Sc.2012 ,Postgraduate candidate
Fixed prosthodontics Department,
Faculty of Dentistry, Minia university
Implant Dentistry has been the fastest growing
treatment modality in dentistry for the past 20 years.
The success in using dental implant to support dental
restorations and reconstructions has been underpinned
by the predictable formation of a bone-to-titanium
interface (osseointegration) after the insertion of a
titanium implant into the human jaw bone. As a result,
the titanium implant becomes a rigid extension of the
jaw and can be utilized as a stable foundation to support
dental restorations and enable normal function of
mastication to be carried out by the patient in comfort
over long periods of time.
Biological consideration in implant therapy
Include :
 soft tissue
 Bone
Healthy soft tissue surrounding a dental implant is
essential for health, function, and esthetics. The
development of the tooth includes the formation of a
biologic connection between the living tissues that
has to be created during the healing process after
placement of the implant. The success of dental
implants is dependent on the establishment of a soft-
tissue barrier that is able to shelter the underlying
osseous structures and the osseointegration
surrounding the implant body.
The esthetics of a dental implant prosthesis depends
on the health and stability of the peri-implant
mucosa. Understanding of soft-tissue healing and
maintenance around dental implants is paramount for
implant success.
 GINGIVAL SHRINKAGE AROUND DENTAL IMPLANTS
During the healing phase following implant placement surgery
(stage 1 surgery) or the trans-mucosal surgery for abutment
connection (stage 2 surgery), the soft tissue re-organises itself
according to the new environment (namely, surrounding a metallic
implant). Noting the histologic observation made byBerglundh
(Berglundh, Lindhe et al. 1991)and other investigator groups
(regarding the orientation of the collagen fibre groups in the peri-
implant gingival tissue) it is easy to appreciate why the peri-implant
gingival tissue appears to shrink during the early stage of wound
healing. The longitudinal arrangement of the major collagen fibre
groups amplifes the process of collagen fibril contraction (as part of
collagen maturation) in the vertical direction.
Clinically, this process is observed as marginal gingiva
shrinkage. In the anterior aesthetic zone, the amount of
gingival shrinkage can be crucial to the success or failure of a
case. Therefore when planning such a case, it is important to
take into account the position and structural integrity of the
labial bone wall which forms form the support base for the
labial gingiva.
 PERI-IMPLANT SOFT TISSUE SEAL
In a dog study(Berglundh, Lindhe et al. 1991), Berglundh and co-workers
compared the similarities in the peri-implant soft tissue to that of the
gingival tissue around teeth. In both cases, the soft tissue consisted of:
1. junctional epithelium component
2. connective tissue component
In both situations, the epithelium adhered to the tooth or titanium surface
in similar fashion.However, in the connective tissue compartment there
were notable differences.
 The peri-implant tissue had a higher Fibre content (and hence a lower
cellular content) than that of gingiva around teeth.
 In addition, the collagen fibres were arranged parallel to the titanium
surface(Çomut, Weber et al. 2001)in contrast to that of the gingiva
which tended to be arranged perpendicular to the cementum surface of
the tooth root with other fibre groups arranged in various patterns
elsewhere in the marginal gingiva. Some of these fibres had previously
been observed to be inserted and embedded into the cementum layer
forming Sharpey’s fibers(Garant and Cho 1979).
 Because the study animals were subjected to plaque control
regime for 8 weeks prior to sacrifice, there was little or no
inflammatory cell infiltrates observed in either the gingiva or peri-
implant tissues. The authors thus concluded that a satisfactory
seal had been formed around the implant/abutment and that this
seal was capable of maintaining tissue health (provided plaque
control is practiced).
 THE KERATINIZED GINGIVAL ZONE
The controversy about the need for a keratinized (attached)
gingival zone around implant supported restorations is an
interesting one. Based on the data from long term implant
success and implant survival studies, there appeared to be
little or no difference in the success rate for implants to be
placed in oral mucosa zone or keratinized gingival zone. It
was therefore argued that there was no convincing evidence
to support the clinical obsession of placing dental implants
in keratinized gingival zone only or to re-create this soft
tissue band after implant placement(Carmichael, Apse et al.
1989).
Nevertheless, the common clinical observation
of frequent plaque accumulation associated with mobile mucosal tissue
around implant restorations and the subsequent soft tissue inflammation (and
hence patient complaints) often lead to the demand for clinical intervention.
Clearly, the amount of peri-implant mucosal tissue movement during
function is influenced by a number of physical variables and is difficult to
measure. Until there is a reliable and accurate way of clinically assessing
soft tissue movement during function, for many clinicians there is a case for
routinely providing a keratinized gingival band around implant restorations
in order to facilitate plaque control and hence reduce the incidence of
plaque-related peri-implant disease. In a recent publication in the
International Journal of Oral & Maxillofacial Implants, in a Current Issues
Forum, the editor posted the question “To minimize complications, is it
essential that implant abutments be surrounded by keratinized
tissue?”(Krygier, Glick et al.).
Common situation encountered where poor oral hygiene
resulted in the breakdown of mucosal tissue around
implant/abutment.
 PERI-IMPLANT TISSUE THICKNESS AND BIOLOGICAL WIDTH
The dimension of the soft tissue attachment to the
implant/abutment surface was considered important
for the maintenance of peri-implant health and for the
overall aesthetics of the final restoration. For many
years, the concept of a biological width was used to
explain the clinical observation of a constant
dimension of dento-gingival junction around teeth
and dental restorations
similar constancy of gingival dimension was observed in
peri-implant tissue as well. In an elegant experiment, the
authors showed that by surgically reducing the thickness
of the gingival flap prior to suturing, a corresponding
crestal bone remodeling will subsequently occur allowing
for the re-establishment of the “biological width” of the
peri-implant soft tissue to its original dimension at the
expense of reduced crestal bone height.
This situation is analogous to the surgical procedure used in “ crown
lengthening” on natural teeth –an attempt to surgically position the
gingival margin more apically and thus allow for an increased
restorative space either for aesthetic reasons or for increasing the
ferrule of coronal structure to improve on the retention of the
planned restoration. This finding had great clinical implications
because it provided a rationale for the careful placement of the soft
tissue at the “correct” and stable position for the final peri-implant
tissue finish. It also explained, at least in part, why it was important
to maintain the alveolar crest in order to support the over-lying soft
tissue
A) Patient related factors:
 Age of the patient:
 Metabolic diseases
 Gender
 Rheumatic disorders
 Smoking
B) Local factor
 Status of the host bone bed and its intrinsic
healing potential
 Improper implant placement and inappropriate
surgical procedure

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Biological considerations of implant therapy

  • 1. Mohammad Mamdouh B.Sc.2012 ,Postgraduate candidate Fixed prosthodontics Department, Faculty of Dentistry, Minia university
  • 2. Implant Dentistry has been the fastest growing treatment modality in dentistry for the past 20 years. The success in using dental implant to support dental restorations and reconstructions has been underpinned by the predictable formation of a bone-to-titanium interface (osseointegration) after the insertion of a titanium implant into the human jaw bone. As a result, the titanium implant becomes a rigid extension of the jaw and can be utilized as a stable foundation to support dental restorations and enable normal function of mastication to be carried out by the patient in comfort over long periods of time.
  • 3. Biological consideration in implant therapy Include :  soft tissue  Bone
  • 4. Healthy soft tissue surrounding a dental implant is essential for health, function, and esthetics. The development of the tooth includes the formation of a biologic connection between the living tissues that has to be created during the healing process after placement of the implant. The success of dental implants is dependent on the establishment of a soft- tissue barrier that is able to shelter the underlying osseous structures and the osseointegration surrounding the implant body.
  • 5. The esthetics of a dental implant prosthesis depends on the health and stability of the peri-implant mucosa. Understanding of soft-tissue healing and maintenance around dental implants is paramount for implant success.
  • 6.  GINGIVAL SHRINKAGE AROUND DENTAL IMPLANTS During the healing phase following implant placement surgery (stage 1 surgery) or the trans-mucosal surgery for abutment connection (stage 2 surgery), the soft tissue re-organises itself according to the new environment (namely, surrounding a metallic implant). Noting the histologic observation made byBerglundh (Berglundh, Lindhe et al. 1991)and other investigator groups (regarding the orientation of the collagen fibre groups in the peri- implant gingival tissue) it is easy to appreciate why the peri-implant gingival tissue appears to shrink during the early stage of wound healing. The longitudinal arrangement of the major collagen fibre groups amplifes the process of collagen fibril contraction (as part of collagen maturation) in the vertical direction.
  • 7. Clinically, this process is observed as marginal gingiva shrinkage. In the anterior aesthetic zone, the amount of gingival shrinkage can be crucial to the success or failure of a case. Therefore when planning such a case, it is important to take into account the position and structural integrity of the labial bone wall which forms form the support base for the labial gingiva.
  • 8.  PERI-IMPLANT SOFT TISSUE SEAL In a dog study(Berglundh, Lindhe et al. 1991), Berglundh and co-workers compared the similarities in the peri-implant soft tissue to that of the gingival tissue around teeth. In both cases, the soft tissue consisted of: 1. junctional epithelium component 2. connective tissue component In both situations, the epithelium adhered to the tooth or titanium surface in similar fashion.However, in the connective tissue compartment there were notable differences.  The peri-implant tissue had a higher Fibre content (and hence a lower cellular content) than that of gingiva around teeth.  In addition, the collagen fibres were arranged parallel to the titanium surface(Çomut, Weber et al. 2001)in contrast to that of the gingiva which tended to be arranged perpendicular to the cementum surface of the tooth root with other fibre groups arranged in various patterns elsewhere in the marginal gingiva. Some of these fibres had previously been observed to be inserted and embedded into the cementum layer forming Sharpey’s fibers(Garant and Cho 1979).
  • 9.  Because the study animals were subjected to plaque control regime for 8 weeks prior to sacrifice, there was little or no inflammatory cell infiltrates observed in either the gingiva or peri- implant tissues. The authors thus concluded that a satisfactory seal had been formed around the implant/abutment and that this seal was capable of maintaining tissue health (provided plaque control is practiced).
  • 10.  THE KERATINIZED GINGIVAL ZONE The controversy about the need for a keratinized (attached) gingival zone around implant supported restorations is an interesting one. Based on the data from long term implant success and implant survival studies, there appeared to be little or no difference in the success rate for implants to be placed in oral mucosa zone or keratinized gingival zone. It was therefore argued that there was no convincing evidence to support the clinical obsession of placing dental implants in keratinized gingival zone only or to re-create this soft tissue band after implant placement(Carmichael, Apse et al. 1989).
  • 11. Nevertheless, the common clinical observation of frequent plaque accumulation associated with mobile mucosal tissue around implant restorations and the subsequent soft tissue inflammation (and hence patient complaints) often lead to the demand for clinical intervention. Clearly, the amount of peri-implant mucosal tissue movement during function is influenced by a number of physical variables and is difficult to measure. Until there is a reliable and accurate way of clinically assessing soft tissue movement during function, for many clinicians there is a case for routinely providing a keratinized gingival band around implant restorations in order to facilitate plaque control and hence reduce the incidence of plaque-related peri-implant disease. In a recent publication in the International Journal of Oral & Maxillofacial Implants, in a Current Issues Forum, the editor posted the question “To minimize complications, is it essential that implant abutments be surrounded by keratinized tissue?”(Krygier, Glick et al.).
  • 12. Common situation encountered where poor oral hygiene resulted in the breakdown of mucosal tissue around implant/abutment.
  • 13.  PERI-IMPLANT TISSUE THICKNESS AND BIOLOGICAL WIDTH The dimension of the soft tissue attachment to the implant/abutment surface was considered important for the maintenance of peri-implant health and for the overall aesthetics of the final restoration. For many years, the concept of a biological width was used to explain the clinical observation of a constant dimension of dento-gingival junction around teeth and dental restorations
  • 14. similar constancy of gingival dimension was observed in peri-implant tissue as well. In an elegant experiment, the authors showed that by surgically reducing the thickness of the gingival flap prior to suturing, a corresponding crestal bone remodeling will subsequently occur allowing for the re-establishment of the “biological width” of the peri-implant soft tissue to its original dimension at the expense of reduced crestal bone height.
  • 15. This situation is analogous to the surgical procedure used in “ crown lengthening” on natural teeth –an attempt to surgically position the gingival margin more apically and thus allow for an increased restorative space either for aesthetic reasons or for increasing the ferrule of coronal structure to improve on the retention of the planned restoration. This finding had great clinical implications because it provided a rationale for the careful placement of the soft tissue at the “correct” and stable position for the final peri-implant tissue finish. It also explained, at least in part, why it was important to maintain the alveolar crest in order to support the over-lying soft tissue
  • 16. A) Patient related factors:  Age of the patient:  Metabolic diseases  Gender  Rheumatic disorders  Smoking
  • 17. B) Local factor  Status of the host bone bed and its intrinsic healing potential  Improper implant placement and inappropriate surgical procedure