Vertical ridge augmentation is sometimes required for dental implant placement. The presentation looks at various conventional and newer techniques for ridge augmentation in the oral cavity.
5. Cologne Classification of Alveolar Ridge Defects
Cologne Classification of Alveolar Ridge Defects 2013. 8th European Consensus Conference of BDIZ EDI
6. Three part codes to describe the effect of the alveolar ridge as comprehensively as
possible with a view to existing therapeutic options:
Part 1: Orientation of the defect
h: horizontal
V: vertical
c: combined
S (or +S): sinus area
Part 2: Reconstruction needs associated with the defect
1. low: <4mm
2. medium: 4-8mm
3. high: >8mm
Part 3: Relation of augmentation and defect region
i: internal, inside the contour
e: external, outside the ridge contour
Cologne Classification of Alveolar Ridge Defects
Cologne Classification of Alveolar Ridge Defects 2013. 8th European Consensus Conference of BDIZ EDI
7. Cologne Classification of Alveolar Ridge Defects
Cologne Classification of Alveolar Ridge Defects 2013. 8th European Consensus Conference of BDIZ EDI
9. Materials that can be used theoretically
Autogenous
Autogenous intraoral
Autogenous extraoral
Block and particulate
Allograft
Demineralised freeze dried bone
Freeze dried bone allograft
Block and particulate
Xenograft
Bovine
Porcine
Block and particulate
Alloplast
Bioactive glass
Calcium phosphate
Calcium sulphate
Calcium carbonate
Synthetic polymers
Particulate HA
Membranes
Resorbable:
Collagen
Poly L lactic acid (PLLA), Poly glycolic acid (PGA), PLGA
Acellular dermal matrix graft
Non resorbable:
Titanium
ePTFE, dPTFE, textured dPTFE
Biological agents
PRF, PRP
Growth factors
BMP
Combinations of the above are also used.
10. Nograft
Allograft
Alloplast
Xenograft
mean loss of buccolingual width at crest level (mm) 2.79 1.63 2.13 1.3
mean loss was in the buccal wall height (mm) 1.74 0.58 0.77 0.57
vital bone formation (%) 41.07 29.93 45.53 35.72
remnant graft material (%) 0 21.75 13.67 19.30
connective tissue (%) 52.53 51.03 38.39 44.42
Jambhekar et al 2015. Clinical and histologic outcomes of socket grafting after flapless tooth extraction: A systematic
review of randomized controlled clinical trials. J Prosth Dent.
Comparison of different grafting materials
• clinical and histologic outcomes of socket grafting after flapless tooth extraction
• minimum healing period of 12 weeks
• systematic review of randomized controlled clinical trials
• xenografts and allografts resulted in the least loss of socket dimensions
• alloplasts had the maximum amount of vital bone and the least amount of remnant
graft material and remnant connective tissue.
11. PTFE (original Goretex membrane)
• synthetic polymer, non-resorbable, biologically inert, chemically non-reactive
Expanded PTFE (ePTFE)
• heating PTFE and then applying force to make expanded PTFE
• highly porous structure - allows ingrowth of bacteria when membrane is exposed
• highly porous structure - allows soft tissue ingrowth, which complicates removal
Dense PTFE (high-density PTFE or dPTFE)
• micro-porous (0.2 micron) material that is impervious to bacteria
• designed to withstand exposure in the oral environment.
• immediately coated with plasma proteins, facilitating cellular adhesion
• removal of dense PTFE is simplified due to the lack of tissue ingrowth
Textured dense PTFE (cytoplast)
• increase in surface area and may increase the pull-out strength of the material
• increased stability in the wound may result in less flap retraction and reduce risk of
membrane movement and loosening
PTFE is also available with titanium reinforcement.
Polytetrafluoroethylene (PTFE)
12. Pagni G et al 2012. Bone repair cells for craniofacial regeneration. Adv Drug Deliv Rev.
Cell therapy
14. Conventional techniques (3 main groups)
• Onlay bone block grafting
• Guided bone regeneration
• Distraction osteogenesis
Other techniques
• Khoury's protocol
• Tenting screws
• Orthodontic bone regeneration
• Fence technique
• I Gen
• 3D printed bone
• Box technique
• Interpositional grafting
Complex surgical procedures
• Le Fort 1 osteotomy
• Nerve transposition (technically not an augmentation)
Techniques for vertical ridge augmentation
16. Bone blocks can be processed in a bone mill to obtain particulate grafts
Tibia grafts can be performed in an outpatient setting
Extraoral bone grafts
Marx & Stevens 2010. Atlas of Oral and Extraoral Bone Harvesting. Quintessence Pub
Site Indication
Tibia 5 – 40 mL uncompressed cancellous marrow
Anterior ilium 30 – 50 mL of corticocancellous marrow
1- 5 cm corticocancellous bone block
Posterior ilium 40 – 120 mL uncompressed cancellous marrow
4 – 12 cm corticocancellous bone block
Cranial bone corticocancellous bone block (onlay graft) for midface, orbital,
zygomatic and nasal reconstructions
17. Bone blocks can be processed in a bone mill to obtain particulate grafts
Comparison of intraoral sites
Marx & Stevens 2010. Atlas of Oral and Extraoral Bone Harvesting. Quintessence Pub
Stern and Barzani 2015. Autogenous Bone Harvest for Implant Reconstruction. Dent Clin N Am
Carlson and Marx 1996. Mandibular Reconstruction Using Cancellous Cellular Bone Grafts. J Oral Maxillofac Surg
Nkenke and Neukam 2014. Autogenous bone harvesting and grafting in advanced jaw resorption: Morbidity, resorption
and implant survival. Eur J Oral Implantol
Site Indication
Chin 0.5 X 1.5 X 6 cm corticocancellous bone block
Mandibular ramus 0.4 X 3 X 5 cm mostly cortical bone block, J graft (thin)
Maxillary tuberosity 1 -3 mL cancellous marrow
19. • Primary wound closure
• Angiogenesis
• Space
• Stability
PASS principles for predictable bone regeneration
Wang and Boyapati 2006. “PASS” principles for predictable bone regeneration. Implant Dent
20. Guided Bone Regeneration and Augmentation around dental implants
Authors Membrane Substrate Vertical bone gain
Simion et al 1994 Titanium
reinforced
ePTFE
Just a blood clot facilitated by
perforating the cortical bone
0.5 to 4mm
(average: 2.97 mm)
Simion et al 2001 Titanium
reinforced
ePTFE
blood clot only, DFDBA, and
autogenous bone chips
>4mm only with autogenous
bone chips.
Simion et al 2007 Titanium
reinforced
ePTFE
autogenous bone chips and
anorganic bovine bone-derived
mineral (1:1)
3.15mm (SD ±1.12 mm)
Urban et al 2009
(1-6 years after
loading)
Titanium
reinforced
ePTFE
autogenous bone chips 5.5mm (±2.29 mm)
(Sinus augmentation included)
Urban et al 2014 Titanium
reinforced
dPTFE
autogenous bone chips and
anorganic bovine bone-derived
mineral (1:1)
5.45mm (SD 1.93)
(Sinus augmentation included)
21. Guided Bone Regeneration and Augmentation around dental implants
Authors Membrane Substrate Vertical bone gain
Urban et al 2017
(1-15 years after
loading)
Titanium
reinforced
ePTFE,
dPTFE or
resorbable
autogenous bone chips alone
or with anorganic bovine bone-
derived mineral (1:1)
5.1mm (± 1.8 mm)
(Sinus augmentation included)
Park et al 2017
(3 year)
Collagen
membrane
Titanium
mesh
Autogenous bone block
Allogenous bone block
Particulated bone
5.13 (± 1.61 mm)
4.54 (± 2.48 mm)
3.90 (± 0.85 mm)
22. 1. Preoperative view
2. Application of a mixture (1:1) of autologous bone and Geistlich Bio-Oss®.
3. Geistlich Bio-Gide® is tightly fixed and pinned and sutured (sausage-like)
4. Primary wound closure
5. 8 months after augmentation
Sausage technique-I Urban
I Urban. Innovative Treatment Concepts in oral and maxillofacial surgery. Geistlich Biomaterials
24. • pioneered by Chin and McCarthy
• the biologic process of new bone formation between the surfaces of bone segments
that are gradually separated by incremental traction.
• a mechanical apparatus, the distraction device, is used to provide gradual, controlled
transport of a mobilized bone segment.
• The prerequisites for optimal bone augmentation of defects via distraction
osteogenesis are a minimum of 6 to 7 mm of bone height above vital structures, such
as neurovascular bundles or air passages/sinus cavities, and a vertical ridge defect of 3
to 8 mm.
• Distraction is usually performed over a period of 30 days
• The advantage of this technique is distraction histogenesis of associated soft tissues,
which provides sufficient keratinized tissue coverage of the increased volume of the
expanded crest. The overall treatment time for alveolar distraction is 3 to 4 months, as
opposed to 6 months with traditional grafting techniques.
Distraction osteogenesis
Maron 2012. Dental Implant Prosthetic Rehabilitation: Vertical Distraction Osteogenesis. Chapter 20.
25. Maron 2012. Dental Implant Prosthetic Rehabilitation: Vertical Distraction Osteogenesis. Chapter 20.
Distraction osteogenesis
• The basic principles include:
• Latency period of 7 days for initial post-surgical soft tissue wound healing
• A distraction phase during which the two pieces of bone undergo gradual
incremental separation at a rate of 0.5–1 mm/day
• A consolidation phase that allows bone regeneration in the created space
26. Laster and Jensen 2016. Distraction Osteogenesis for Height and Width of the Alveolar Crest. Chapter 21
Distraction osteogenesis
27. Distraction osteogenesis. Stabilization of the ridge using a unidirectional vector distractor and successful
vertical ridge compensation in the anterior maxilla.
Distraction osteogenesis
28. • Onlay block bone grafting- minor related to the morbidity from harvesting the block
and graft shrinkage.
• GBR- reported complication rates were 0–45.5% and complications were mainly
related to membrane exposure.
• distraction osteogenesis- complication rates were higher (10–75.7%), and
complications included fractures of the distractor, neurologic alterations, fractures of
the distracted or basal bone, and lingual or palatal inclination of the distracted bone.
Complication rates
Rocchietta et al 2008. Clinical outcomes of vertical bone augmentation to enable dental implant placement: a
systematic review. J Clin Periodontol
30. Khoury technique- Micro-Saw®
Khoury and Hanser 2015. Mandibular Bone Block Harvesting from the Retromolar Region: A 10-Year Prospective
Clinical Study. Int J Oral Maxillofac Implants
Gluckman and Du Toit 2015. Reconstruction of a single-tooth traumatic defect in the anterior maxilla using the
Khoury bone plate graft.
31. 1. Intraoral view of the defect in the posterior right mandible.
2. Cortical perforations and tenting screws
3. Geistlich Bio-Oss® and autologous bone (1:1)
4. ePTFE barrier membrane secured with two fixation screws
Tenting screws and particulate bone graft
M Simion. Innovative Treatment Concepts in oral and maxillofacial surgery. Geistlich Biomaterials
32. Orthodontic bone regeneration
de Molon et al 2013. Forced orthodontic eruption for augmentation of soft and hard tissue prior to implant placement
33. 1. Preoperative radiograph depicting the severe bony atrophy in the posterior mandible.
2. Fixation of the pre-formed osteosynthesis plate with miniscrews.
3. Autologous bone mixed with Geistlich Bio-Oss®
4. osteosynthesis plate is covered with Geistlich Bio-Gide® and the tensile collagen
membrane is pinned down.
Fence technique
M Merli. Innovative Treatment Concepts in oral and maxillofacial surgery. Geistlich Biomaterials
37. • Poly D,L-lactide acid (PDLLA) resorbable mesh plates (KLS Martin) placed bilaterally
• Allograft particulate bone covered with a resorbable bovine pericardium membrane
Box technique- Andrea Menoni
Menoni et al 2012. Full-Arch Vertical Reconstruction of an Extremely Atrophic Mandible With “Box Technique.” A Novel
Surgical Procedure: A Clinical and Histologic Case Report. Implant Dent
38. 5 to 7 mm of available bone
above the inferior alveolar nerve
An interpositional bone graft
is placed after elevation of
a pedicled segmental alveolar
osteotomy.
Four years later, bone levels
appear unchanged around
2 restored osseointegrated
implants. The osteotomy site
is not visible.
Jensen 2006. Alveolar Segmental “Sandwich” Osteotomies.... J Oral Maxillofac Surg
Interpositional bone graft/ Sandwich technique
39. 1. Exposure of the alveolar ridge and buccal bone
2. Horizontal and vertical osteotomies of the distracted segment.
3. upward lift of the transported segment, achieving a height gain of 7 mm.
4. Geistlich Bio-Oss® Block
5. fixed with miniplates and miniscrews 6. Geistlich Bio-Gide®
Interpositional grafting with xenograft block
P Felice. Innovative Treatment Concepts in oral and maxillofacial surgery. Geistlich Biomaterials
40. Materials used to print
• Titanium
• PEEK
• Hydroxypatiite
• Calcium phosphate
3D Printed bone
• CT Bone
• Calcium phosphate
• (Xilloc Medical Ltd)
• Hyperelastic bone
• hydroxyapatite and either
polycaprolactone or
poly(lactic-co-glycolic
acid)
42. • vertical ridge augmentation is safe and predictable but highly technique‐sensitive
• onlay bone block grafting remains the gold standard for vertical ridge augmentation.
• autogenous bone particles combined with a bone substitute material and covered
with a barrier membrane has been highly effective in vertical ridge augmentation
• vertically augmented bone responds to implant placement like native, non-
regenerated bone.
Conclusion
44. (a) implants can be placed in adjacent sites
(b) short implants can be used
(c) pink ceramic can be used to create an illusion of “normal” soft-tissue anatomy.
Alternatives to vertical ridge augmentation
Carranza’s Clinical Periodontology. 2015.12th Ed.