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1	
  
The	
  Chemical	
  
Level	
  of	
  
Organiza4on	
  	
  
BIOL	
  121:	
  A&P	
  I	
  
Chapter	
  2
Rob	
  Swatski	
  
Associate	
  Professor	
  of	
  Biology	
  
HACC	
  –	
  York	
  Campus	
  
Part	
  1:	
  Inorganic	
  
Chemistry	
  
Textbook images - Copyright © 2014 John
Wiley & Sons, Inc. All rights reserved.
2	
  
3	
  
Contains	
  
Mass	
  
Occupies	
  
Space	
  MaKer	
  
4	
  
How	
  is	
  MaKer	
  
Organized?	
  
Elements	
  
Trace	
  
Elements	
  
5	
  
The	
  4	
  Most	
  
Abundant	
  
Elements	
  of	
  
Life	
  
O	
  
C	
  
H	
  
N	
  
6	
  
The	
  Next	
  4	
  
Most	
  
Abundant	
  
Elements	
  of	
  
Life	
  
Ca	
  
P	
  
K	
  
S	
  
MAJOR ELEMENTS
(about 96% of total)
LESSER ELEMENTS
(about 3.6% of total)
TRACE ELEMENTS
(about 0.4% of total)
8	
  
9	
  
10	
  
Atomic	
  
Structure	
  
Nucleus	
  
Protons	
  
(+)	
  
Neutrons	
  
(0)	
  
Electron	
  
Cloud	
  
Electrons	
  
(-­‐)	
  
11	
  
How	
  Are	
  an	
  Atom’s	
  Electrons	
  
Organized?	
  
3rd	
  Shell	
  
2nd	
  Shell	
  
1st	
  Shell	
  
Nucleus	
  
12	
  
13	
  
#	
  of	
  
Protons	
  
#	
  of	
  
Electrons	
  
Electrically	
  Neutral	
  Atom	
  
14	
  
Atomic	
  
Number	
  
#	
  of	
  
Protons	
  
15	
  
#	
  of	
  
Neutrons	
  
#	
  of	
  
Protons	
  
Atomic	
  
Mass	
  
16	
  
17	
  
18	
  
Isotopes	
  
Same	
  #	
  of	
  
protons	
  
Different	
  #	
  
of	
  neutrons	
  
19	
  
Radioisotopes	
  (tracers)	
  
I-­‐131	
  thyroid	
  study	
  
20	
  
Ions	
  
Anions	
  
(-­‐)	
  
Ca4ons	
  
(+)	
  
Gain	
  e-­‐	
   Lose	
  e-­‐	
  
21	
  
Free	
  Radicals	
  
22	
  
23	
  
24	
  
Stable	
  
Atoms	
  
8	
  
valence	
  
e-­‐	
  
Unstable	
  
Atoms	
  
<	
  8	
  
valence	
  
e-­‐	
  
25	
  
26	
  
27	
  
28	
  
29	
  
Ionic	
  
Bonds	
  
30	
  
dissocia4on	
  à	
  electrolytes	
  
31	
  
Covalent	
  Bonds	
  
Single	
   Double	
   Triple	
  
32	
  
Types	
  of	
  Covalent	
  
Bonds	
  
Nonpolar	
  
Polar	
  
Molecules	
  
33	
  
Nonpolar	
  Covalent	
  Bonds	
  
34	
  
35	
  
Polar	
  Covalent	
  Bonds	
  
36	
  
37	
  
38	
  
Chemical	
  
Reac4ons	
  
Metabolism	
  
Physiology	
  
39	
  
Chemical	
  Equa4ons	
  
40	
  
Total	
  
Mass	
  of	
  
Reactants	
  
Total	
  
Mass	
  of	
  
Products	
  
Law	
  of	
  Conserva4on	
  of	
  Mass	
  
41	
  
Total	
  
Energy	
  of	
  
Reactants	
  
Total	
  
Energy	
  of	
  
Products	
  
Law	
  of	
  Conserva4on	
  of	
  Energy	
  
42	
  
Energy	
  
Poten4al	
  
Chemical	
  Kine4c	
  
43	
  
44	
  
45	
  
46	
  
47	
  
Energy	
   Energy	
  Exergonic	
  
Reac4on	
  
48	
  
Energy	
   Energy	
  Endergonic	
  
Reac4on	
  
Coupled	
  Reac4ons	
  
49	
  
50	
  
Ac4va4on	
  
Energy	
  
51	
  
Increase	
  
Reac4on	
  Rate	
  
Decrease	
  
Ac4va4on	
  
Energy	
  
Catalysts	
  
Enzymes	
  as	
  
Catalysts	
  
52	
  
53	
  
54	
  
55	
  
Types	
  of	
  
Chemical	
  
Reac4ons	
  
Synthesis	
  
Decomposi4on	
  
Exchange	
  
Reversible	
  
A	
   B	
   AB	
  
Synthesis	
  (Anabolism)	
  
56	
  
57	
  
Two hydrogen
molecules
One oxygen
molecule
Two water
molecules
Combine to form
Synthesis	
  (Anabolism)	
  
AB	
   A	
   B	
  
Decomposi4on	
  (Catabolism)	
  
59	
  
Breaks down into
One methane
molecule
One carbon atom Two hydrogen
molecules
Decomposi4on	
  (Catabolism)	
  
AB	
   CD	
   AC	
   BD	
  
Exchange	
  
HCl	
  +	
  NaHCO3	
  	
  	
  	
  	
  	
  	
  	
  	
  H2CO3	
  +	
  Na+Cl-­‐	
  
61	
  
Hydrochloric
acid
Sodium
bicarbonate
Carbonic acid Sodium
chloride
Exchange	
  
A	
   B	
   AB	
  
Reversible	
  
63	
  
64	
  
Oxida4on	
  
e-­‐	
  
e-­‐	
  e-­‐	
  
HIGH	
  
low	
  
65	
  
Reduc4on	
  
e-­‐	
  
e-­‐	
  
e-­‐	
  
HIGH	
  
low	
  
66	
  
Compounds	
  
Inorganic	
  
No	
  
Carbon	
  
Small	
  
Simple	
  
Ionic	
  
bonds	
  
Organic	
  
Carbon-­‐
based	
  
Large	
  
Complex	
  
Covalent	
  
bonds	
   67	
  
68	
  
Water	
  
69	
  
Dehydra4on	
  
Synthesis	
  
70	
  
Hydrolysis	
  
71	
  
Solute	
   Solvent	
   Solu4on	
  
72	
  
Hydrophilic	
  
Polar	
  
covalent	
  
Water-­‐
soluble	
  
Hydrophobic	
  
Nonpolar	
  
covalent	
  
Water-­‐
insoluble	
  
73	
  
Proper4es	
  of	
  
Water	
  
74	
  
High	
  Heat	
  Capacity	
  
High	
  Heat	
  of	
  
Vaporiza4on	
  
How	
  do	
  they	
  
benefit	
  the	
  human	
  
body?	
  
75	
  
Cohesion	
  
How?	
  
76	
  
Surface	
  Tension	
  
How?	
  
77	
  
Mixtures	
  
Solu4on	
  
Colloid	
  Suspension	
  
78	
  
79	
  
80	
  
81	
  anions	
   ca4ons	
   both	
  
pH	
  
82	
  
Acidic	
  
[H+]	
  >	
  [OH–]	

Neutral	
  
[H+]	
  =	
  [OH–]	

Basic	
  
[H+]	
  <	
  [OH–]	

7	

0	

14	

83	
  
84	
  
85	
  
86	
  
Buffering	
  
Systems	
  
87	
  
Carbonic	
  
Acid	
  
H2CO3	
  
Bicarbonate	
  
ion	
  	
  
HCO3
-­‐	
  
	
  
Carbonic	
  acid-­‐Bicarbonate	
  
buffer	
  system	
  
H+	
  
OH+	
  
88	
  
The	
  Chemical	
  
Level	
  of	
  
Organiza4on	
  	
  
BIOL	
  121:	
  A&P	
  I	
  
Chapter	
  2
Rob	
  Swatski	
  
Associate	
  Professor	
  of	
  Biology	
  
HACC	
  –	
  York	
  Campus	
  
Part	
  2:	
  Organic	
  
Chemistry	
  
Textbook images - Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
89	
  
90	
  
Bonds	
  with	
  
variety	
  of	
  
elements	
  
Diverse	
  sizes	
  &	
  
shapes	
  
More	
  insoluble	
  
in	
  water	
  
Many	
  covalent	
  
bonds	
  
Organic	
  
molecules	
  
Monomers	
  à	
  
Macromolecules	
  
Proper4es	
  of	
  Carbon-­‐Based	
  Molecules	
  
91	
  
Func4onal	
  Groups	
  
92	
  
Estradiol	

 Testosterone
93	
  
Carbon	
  Molecules	
  
94	
  
95	
  
Carbohydrates:	
  
Func4ons	
  
Energy	
   Structure	
   Storage	
  
96	
  
Structure	
  
C,	
  H,	
  O	
  
C-­‐H2O	
  
Size	
  
Simple:	
  
glucose	
  
Complex:	
  
starch	
  
97	
  
3	
  Major	
  Groups	
  of	
  
Carbohydrates	
  
Mono-­‐
saccharides	
  
Disaccharides	
   Polysaccharides	
  
Monosaccharides	
  
98	
  
C6H12O6	
  
Glucose
(C6H12O6)
Sucrose
(C12H22O11)
Dehydra4on	
  synthesis	
  
and	
  hydrolysis	
  of	
  sucrose	
  
Dehydration
synthesis
Fructose
(C6H12O6)
Hydrolysis
Water
Disaccharides	
  
Lactose	
  Intolerance	
  
100	
  
101	
  
Polysaccharides	
  
largest	
  
carb	
  
100’s	
  of	
  
mono’s	
  
glycogen	
  
102	
  
C,	
  H,	
  O	
   hydrophobic	
  
few	
  polar	
  
covalent	
  
bonds	
  
insoluble	
  in	
  
water	
  
glycerol	
  &	
  1-­‐3	
  
faZy	
  acids	
  
fats	
  &	
  oils	
  
Lipids	
  –	
  General	
  Characteris4cs	
  
103	
  
Lipid	
  Structure	
  
104	
  
Triglyceride	
  Structure	
  
105	
  
Func4ons	
  of	
  Triglycerides	
  
Protec4on	
   Insula4on	
  
Energy	
  
source	
  
short-­‐	
  or	
  
long-­‐term	
  
106	
  
107	
  
Phospholipids	
  
Cell	
  structure	
  
&	
  func[on	
  
Plasma	
  
membrane	
  
Amphipathic	
  
108	
  
Head	
  
Polar	
  
Hydrophilic	
  
Glycerol	
  &	
  
phosphate	
  
Tails	
  
Nonpolar	
  
Hydrophobic	
  
2	
  FaZy	
  acids	
  
Phospholipid	
  
Structure	
  
109	
  
110	
  
Steroids	
  
111	
  
112	
  
113	
  
Proteins	
  
C,	
  H,	
  O,	
  N	
  
Diverse	
  
shapes	
  &	
  
sizes	
  
Amino	
  acids	
  
114	
  
Func4ons	
  of	
  Proteins	
  
Structure	
  &	
  
protec[on	
  
Regulate	
  
metabolism	
  
Muscle	
  
contrac[on	
  
Chemical	
  &	
  
organelle	
  
transport	
  
115	
  
Amino	
  Acids	
  
Amino	
  group	
  
-­‐	
  NH2	
  
Carboxyl	
  
group	
  
-­‐	
  COOH	
  
R	
  group	
  
116	
  
117	
  
118	
  
119	
  
Primary	
  
Secondary	
  
Ter4ary	
  
Quaternary	
  
Levels	
  of	
  Protein	
  Structure	
  
120	
  
Primary	
  Structure	
  
121	
  
Secondary	
  Structure	
  
122	
  
Ter4ary	
  Structure	
  
123	
  
Quaternary	
  Structure	
  
124	
  
125	
  
Denatura4on	
  
Enzymes	
  =	
  Catalysts	
  
126	
  
Substrates	
  
Ac4ve	
  
Site	
  
Enzyme	
  
127	
  
Enzymes	
  =	
  Catalysts	
  
128	
  
How	
  do	
  Enzymes	
  Increase	
  
Reac4on	
  Rate?	
  
Increase	
  
collision	
  
frequency	
  
Lower	
  
ac[va[on	
  
energy	
  
Properly	
  
orient	
  
molecules	
  
129	
  
130	
  
C,	
  H,	
  O,	
  N,	
  P	
   Nucleo[des	
  
DNA	
   RNA	
  
Regulates	
  cell	
  
ac[vi[es	
  
Guides	
  
protein	
  
synthesis	
  
Nucleic	
  Acids	
  
131	
  
Nucleo4des	
  
Nitrogenous	
  
Base	
  
Pentose	
  
Sugar	
  
Phosphate	
  
Group	
  
132	
  
133	
  
134	
  
RNA	
  
Single	
  
stranded	
  
Ribose	
  =	
  
sugar	
  
Uracil	
  =	
  
base	
  
135	
  
3	
  Types	
  of	
  RNA	
  
mRNA	
   rRNA	
   tRNA	
  
136	
  
Adenosine	
  Triphosphate	
  (ATP)	
  
Primary	
  
source	
  of	
  
chemical	
  
poten[al	
  
energy	
  
Powers	
  
muscle	
  
contrac[on,	
  
chemical	
  
transport,	
  
organelle	
  
movement	
  
Adenine,	
  
ribose,	
  and	
  3	
  
phosphate	
  
groups	
  
137	
  
138	
  
Energy	

P	

 P	

 P	

 P	
  i	

 P	

 P	

Adenosine	

 Adenosine	

ADP	

ATP	

Reacts	
  with	
  
H2O	

Energy	
  
139	
  
ATP	
  Cycle	
  
P	
  i	
  ADP	
   +	
  
H2O	
  ATP	
   +	
  ATP	
  
ATP	
  hydrolysis	
  
ATP	
  synthesis	
  
140	
  

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