Complete article on hormones, cosmetic & personal care products, pharmaceuticals its types, functions, design, workflow, uses and applications.

1. Article on hormones, cosmetics &
personal care products, pharmaceutical
& medicinal drugs
ARTICLE WRITTEN AND PUBLISHED
BY
WWW.WORLDOFCHEMICALS.COM

2. History
 Biochemicals, chemical messengers, mood swingers,
plant growth regulators what ever may be the names
for hormones plays vital role in humans, animals and
even in plants. Hormones produced in one part of
body/place and travel through bloodstream to
different parts of the body.

3. Types of hormones and applications
 Hormones basically involved in
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Growth – in humans, animals and plants
Digestion process – in humans, animals
Metabolism – in humans, animals
Mood changes – in humans
Sexual development – in humans, animals
Reproduction process – in humans, animals, plants
 By this functions hormones are divided into following two groups
 Human hormones
 Animal hormones
 Plant hormones

4. Hormones classification
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Peptide hormones
Lipids derived hormones
Phospholipids derived hormones
Any sort of imbalances in hormone levels can causes
Anxiety
Sleep Disorders
Depression
Poor concentration
Nervousness
Skin Problems etc
Plant hormones

5. Plant hormones and its functions
 Auxins – helps in vegetative propagation
 Cytokinins – for cell division, root proliferation
 Gibberellins – for flowering, seed dormancy
 Abscisic Acid – for abscission of flowers, leaves,
fruits
 Ethylene – for fruit ripening
 Polyamines – to promote plant regeneration

6. Human hormones
 Human hormones
 In various human development stages hormonal secretion levels
will change. At the age of 10 to 11 years in humans, hormones
related to puberty leads to change in mental and physical growth.
 Still in teenagers hormones causes
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Self-consciousness
Quick mood changes
Quick decision changes
Attraction towards opposite genders
At the age of teenage people will fall in love, reason behind this is all
because of high levels of hormones. There are certain stages of love

7. Human hormones cont …
 Lust
 Attraction towards opposite gender
 Commitment
 All these emotions are because of love chemicals. These love chemicals include
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Adrenaline – causes excitement, attraction,anxiety
Estrogen – sex drive factor in both male and females
Testosterone - sex drive factor in both male and females
Dopamine – it’s a pleasure chemical
Norepinephrine – raises excitement in heart
Serotonin – released attraction stage of love
Oxytocin – for long term relationships between couples
Vasopressin – vital role in long-term commitment
Endorphins – causes feelings like attachment, comfort, anxiety, relieve stress,
relieve pain

8. Cosmetics and personal care products
 Human’s skin is the largest organ in their body and when you
apply cosmetics, personal care products, perfumes, fragrances it will
absorb soon and show immediate results.
 So most of the teenage people both genders shows interest in body
cleansing, beautifying, promoting attractiveness, altering the
appearance. These type of products termed as cosmetics and
personal care products.
 Cosmetic and personal care products are applied to appear more
attraction and look different from others.
 Cosmetic products used in the form of powders, solutions, gels,
suspensions, pastes, lotions. These products can be used starting
from head to toe of human body.

9. Chemicals involved in the preparation of cosmetics and
personal care
 Phthalates
 Formaldehyde
 Parabens
 Titanium dioxide
 Zinc oxide
 Glycerin
 Hyaluronic acid
 Collagen
 Urea

10. History of cosmetics and personal care products
 Cosmetic manufacturers before releasing their products into market
they will be testing for safety and efficacy on animals like mice,
guinea pigs, rats, and rabbits. Some cosmetic manufacturers remove
controversial and hazardous chemicals from their cosmetic
products.
 Along with the cosmetic products people widely use perfumes,
fragrances to their body, cloths.
 All civilizations, from ancient to contemporary world, have used
fragrances for a wide spread of functions. Before the appearance of
organic synthesis, fragrances were restricted to those found in the
form of oils, balsams, exudates, and resins. With development of
organic synthesis during the 19th Century, fragrance chemistry
advanced into industrial synthesis and distribution.

11. History of cosmetics and personal care products
cont..
 Usage of fragrances was started by Egyptians, Greeks, Rome people
and it continues in 20th centaury. The ancient people prepared
cosmetics and personal care products from herbs, plant sources.
 A fragrance was also used for tombs to preserve human body,
antidotes for toxins, health improver agents.
 Some perfumes according to their chemical composition and origin
from where they derived or extracted stays on body and even they
will exerts perfumery action with immediate or slow response.
 Fragrance chemistry is an ever dynamic field that relies on the
trends of the age. Recent trends in fragrance chemistry include
floral scents, fruity scents, spicy scents, rose flower scents.
Fragrance chemistry is an industrially important science that needs
the constant discovery of new and distinctive odorants.

12. Classification of fragrances
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Fragrances are classified into following type based on origin
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Most of the synthetic fragrances are made of
Natural fragrances
Synthetic fragrances
Terpenoids – Geraniol, Linalool, Citronellol, Citronellal, Citral
Hemiterpenoids – Prenyl acetate, Benzoate
Cyclic Monoterpenes - l-menthol, l-carvone, α-terpineol
Menthol
Bicyclic Monoterpenoids – Camphene
Sesquiterpenoids – Geranylacetone, Bisabolol
Diterpenoids
Ambergris
Benzoin
Calone
Castoreum
Hedione
Indole

13. Pharmaceuticals and medicinal drugs
 At teenage level due to peek hormonal levels some people will
addicted to drugs. This is termed as drug addiction or substance
addiction.
 Neurochemicals or neurotransmitters like dopamine and serotonin
are the real culprit behind drug addiction. Dopamine motivates us
to do what’s necessary to fulfill our desires, and once a desire has
been met, the nucleus accumbens triggers the release of serotonin.
Serotonin, which helps us feel satiated and contributes to feelings of
happiness and well-being, then inhibits the compelling motivation
of dopamine.
 Once people habituated to taking drugs, there is a possibility of
decline of their health. To treat their health pharmaceuticals or
drugs or medicines or chemotherapeutic agents required.

14. Pharmaceuticals and medicinal drugs cont..
 So pharmaceuticals or drugs can be defined as ‘chemicals substances that
are used in medical diagnosis, curing, treatment, prevention in humans,
animals, and plants’.
 Pharmaceutical manufacturers produce drugs/medicines and released into
the market. Before releasing the drugs into market pharmaceutical
manufacturers will conduct following tests/studies on animals, healthy
volunteers. Basically in theses studies scientists check for the safety,
efficacy, pharmacodynamics and pharmacokinetics of drugs.
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Pre-clinical studies
Phase I
Phase II
Phase III
Post market Surveillance

15. Drugs used for chemotherapy or pharmacotherapy
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Veterinary drugs
Musculoskeletal drugs
Hormonal drugs
Antidotes
Antiparasitic drugs
Antibiotics
Antineoplastic drugs
Dermatological drugs
Gastrointestinal drugs
Cardiovascular drugs
Proton pump inhibitor drugs
Pharmaceutical raw materials
Pharmaceutical intermediates

16. Drugs used for chemotherapy or pharmacotherapy
complete details
 Veterinary medicines
 Veterinary medicine given to both domestic animals, wild animals
for the purpose of prevention and treatment of diseases. Veterinary
medicine given to animals through via feed, water, nervous system.
 Musculoskeletal drugs
 Musculoskeletal drugs diagnose acute, sub-acute and chronic non-
surgical musculoskeletal complaints like pain in the muscles,
tendons, ligaments and joints.
 Hormone drugs
 Hormone drugs are hormone replacements for patients with thyroid
problems and other hormonal imbalance problems. Hormonal
medicine also used for regulation of ovulation and menstruation.

17. Drugs used for chemotherapy or pharmacotherapy
complete details cont..
 Antidotes
 Antidote are pharmaceuticals neutralizes counteracts with harmful
effects of poison. Antihistamines used for seasonal allergic itching,
hay fever, reduces nausea, vomiting, anaphylaxis.
 Antiparasitic drugs
 Antiparasitic drugs are pharmaceuticals diseases caused by
nematodes, cestodes, trematodes, protozoa, and amoeba.
Antiparasitic drugs are highly effective, safe, cost effective drugs.
 Antibiotics
 Antibiotics works selectively by killing particular type of bacteria
without harming living cells. Antibiotics interfere with the
formation of the bacterium’s cell wall or its cell contents there by it
kill or prevent the growth of bacteria.

18. Drugs used for chemotherapy or pharmacotherapy complete
details cont..
 Antineoplastic drugs
 Anticancer drugs also termed as antineoplastic agents. Anticancer drugs effective
for hormone-sensitive tumors, malignancies, cancerous cells growth. Anticancer
drugs acts at specific points of the anaphase or metaphase of cell cycle.
 Dermatological drugs
 Dermatological drugs exert chemical physical action on the skin in order to assist in
treatment of skin diseases. Dermatological drugs composed with other medicines
like local anesthetics, cleansing agents, anti-inflammatory agents, anti-infective
agents, emollients, and astringents, agents to treat acne, anti-virals, and anti-fungal.
 Gastrointestinal drugs
 Gastrointestinal drugs are pharmaceuticals neutralize the acid secretions of
stomach, regulates gastrointestinal motility, improve digestion and stimulate the
production of bile by the liver. Naproxen, ranitidine, clebopride, betazole,
impromidine are widely used gastrointestinal agents.

19. Drugs used for chemotherapy or pharmacotherapy complete
details cont..
Cardiovascular drugs
 Cardiovascular drugs are pharmaceuticals cures cardiovascular diseases heart attack, stroke,
hypertension, congestive heart failure and vascular death. Digoxin, bisoprolol, lidocaine,
midodrine are widely used cardiovascular drugs.
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Proton pump inhibitor drugs
Proton pump inhibitors are pharmaceuticals works against acid refluxes in stomach walls,
peptic ulcers, and stomach ulcers. Nexium, Prilosec, Protonix, Prevacid, AcipHex, Kapidex is
the commonly used proton pump inhibitors drug brands.
Pharmaceutical raw materials
Pharmaceutical raw materials are two type’s active ingredients and inactive ingredients.
Pharmaceutical raw materials are needed to make medicines and drugs. Inactive ingredients
are ineffective pharma raw materials used to create pills.
Pharmaceutical intermediates
Pharmaceutical intermediates are fine chemical products and important principle ingredients
in manufacturing of synthetic medicines.