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ANTIMICROBIAL USED AS
PRESERVATIVE
Prepared by : Aditya Singh
M.Pharma 1st year
2nd semester
MPH 204T
Antimicrobial
• An antimicrobial is an agent that kills
microorganisms or stops their growth.
• The use of antimicrobial medicine to treat
infection is known as antimicrobial
chemotherapy.
• The main class of antimicrobial agents are
disinfectants and antiseptics.
1
• Disinfectants : it kills a wide range of microbes
on non-living surface to prevent the spread of
illness.
• Antiseptics : which are applied to living tissue
and prevent the growth of causing of disease
causing microorganism.
2
Preservative
Preservative is a substance used to prevent
foodstuffs, wood or other materials against
decay.
Preservative is a chemical that added to
products such as food, beverages,
pharmaceutical drugs, paints, cosmetics to
prevent decomposition by microbial growth.
3
Cosmetic product with antimicrobial
effect
This preparation has ability to provide consumer’s
protection against the presence of antimicrobial
compounds having bactericidal effect.
Products like mouthwashes, skin disinfectant and
soaps present this characteristic.
Currently the limit between drugs and cosmetic
product with antimicrobial effect is increasingly
indistinct.
5
Product
• Deodorants : Inhibit the staphylococi bacteria and
metabolism responsible for degradation of sweat
and subsequent production of unpleasant body
odor active ingredent Aluminum chlorohydrate,
alcohol.
• Anti dandruff shampoos : reduces the mlassezia
and inhibit yeast growth and active ingredient is
salicylic acid, imidazole derivatives.
• Toothpaste : prevent bacterial growth and plaque
formation active ingredient is alcohal . 6
Antimicrobial preservative
• These are the substances added to nonsterial
dosage forms to protect them from micro-
biological growth or from microorganism that
are introduced inadvertently during or
subsequent to the manufacturing process.
7
Properties of ideal preservative
• Effective at a low, nontoxic concentration
against a wide variety of organisms.
• Chemically stable
• Soluble at a required amount of concentation
• Absence of odor, taste, color.
• Reasonable cost.
8
Antimicrobial list preservatives
• Benzalkonium chloride
• Benzoic acid
• Cetrimonium bromide
• Chlorocresol
• Methylparaben
• Phenoxyethanol
• Propylparaben
• Thimerosal
9
Thanking you…

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Antimicrobial used as preservative

  • 1. ANTIMICROBIAL USED AS PRESERVATIVE Prepared by : Aditya Singh M.Pharma 1st year 2nd semester MPH 204T
  • 2. Antimicrobial • An antimicrobial is an agent that kills microorganisms or stops their growth. • The use of antimicrobial medicine to treat infection is known as antimicrobial chemotherapy. • The main class of antimicrobial agents are disinfectants and antiseptics. 1
  • 3. • Disinfectants : it kills a wide range of microbes on non-living surface to prevent the spread of illness. • Antiseptics : which are applied to living tissue and prevent the growth of causing of disease causing microorganism. 2
  • 4. Preservative Preservative is a substance used to prevent foodstuffs, wood or other materials against decay. Preservative is a chemical that added to products such as food, beverages, pharmaceutical drugs, paints, cosmetics to prevent decomposition by microbial growth. 3
  • 5. Cosmetic product with antimicrobial effect This preparation has ability to provide consumer’s protection against the presence of antimicrobial compounds having bactericidal effect. Products like mouthwashes, skin disinfectant and soaps present this characteristic. Currently the limit between drugs and cosmetic product with antimicrobial effect is increasingly indistinct. 5
  • 6. Product • Deodorants : Inhibit the staphylococi bacteria and metabolism responsible for degradation of sweat and subsequent production of unpleasant body odor active ingredent Aluminum chlorohydrate, alcohol. • Anti dandruff shampoos : reduces the mlassezia and inhibit yeast growth and active ingredient is salicylic acid, imidazole derivatives. • Toothpaste : prevent bacterial growth and plaque formation active ingredient is alcohal . 6
  • 7. Antimicrobial preservative • These are the substances added to nonsterial dosage forms to protect them from micro- biological growth or from microorganism that are introduced inadvertently during or subsequent to the manufacturing process. 7
  • 8. Properties of ideal preservative • Effective at a low, nontoxic concentration against a wide variety of organisms. • Chemically stable • Soluble at a required amount of concentation • Absence of odor, taste, color. • Reasonable cost. 8
  • 9. Antimicrobial list preservatives • Benzalkonium chloride • Benzoic acid • Cetrimonium bromide • Chlorocresol • Methylparaben • Phenoxyethanol • Propylparaben • Thimerosal 9