This document discusses anesthetic considerations for spine surgery. It covers various types of spine surgeries and their associated risks. Prone positioning presents challenges like difficult airway and eye injuries that can be prevented with proper positioning and monitoring of vital parameters. Blood loss is a major concern, especially in complex procedures, so measures like hypotensive anesthesia and antifibrinolytic therapy are used. Neurological monitoring techniques like SSEP and MEP are employed to detect injuries. Recent advances in navigation, endoscopy and robotics have made surgeries less invasive with benefits like lower blood loss and faster recovery. Regional anesthesia and specialized equipment allow addressing anesthesia needs for complex cases and new techniques.