This document discusses various techniques for providing anesthesia during ophthalmic surgery, including sub-tenon's block, peribulbar block, retrobulbar block, and subconjunctival block. It describes the aims, sites of injection, patient positioning, local anesthetic agents used, techniques, advantages, disadvantages, and potential complications for each type of block. The sub-tenon's block provides akinesia and anesthesia through injection into the subtenon space using lignocaine or bupivacaine. The peribulbar and retrobulbar blocks both aim to block orbital nerves but through different injection sites and techniques. The subconjunctival block only provides anterior segment anesthesia without akinesia.
Principles and technique of pneumatic retinopexy (Dr. Avuru C.J).pptxAVURUCHUKWUNALUJAMES1
Retinal detachment surgeries, principles and technique of pneumatic retinopexy, current trend in retinal detachment surgeries, development of skills in binocular indirect ophthalmoscopic examination, residency traning presentation, University college hospital Ibadan, Oyo state Nigeria, Vitreo-retinal subspecialty training, West african college of surgeons, federal teaching hospital, Lokoja, Kogi state, Nigeria.
This PowerPoint presentation offers a succinct and technical analysis of the maxillary nerve block procedure. Explore the anatomical considerations, injection techniques, indications, and potential complications of this essential dental and medical intervention.
Conjunctivitis is an inflammation or swelling of the conjunctiva. The conjunctiva is the thin transparent layer of tissue that lines the inner surface of the eyelid and covers the white part of the eye. Often called "pink eye".
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
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Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
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Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
2. Anesthesia for Ophthalmic Surgery
dr. Frenky
ANESTHESIA
Infiltration Intracameral Topical Nerve Blocks
Retrobulbar
Block
Peribulbar
Block
Subtenon’s
Block
Subconjunctival
Block
Local General
Classification
3. Anesthesia for Ophthalmic Surgery
dr. Frenky
Generic name
(trade name)
Concentration
(Max Dose)
Onset of
action
Duration of
action
Mayor advantages /
disadvantages
0.5% - 2%
(500mg)
4-5 min
• 40-60 min
• 120 min (with
epinephrine)
Spreads readily without
hyaloronidase/
Increased BP with
hyaloronidase.
0.25% - 0.75% 5-10 min
• 5-6 hrs.
• 8-12 hrs (with
epinephrine)
Long duration of
action/increased
toxicity of extra ocular
muscles.
0.5% - 2% 4-5 min 2-3 hrs.
Peripheral nerve block
Less neurotoxicity
Local Anesthetic agents
Lidocaine*
(Xylocaine,
anestacaine)
Bupivacaine*
(Sensorcaine,
Marcaine)
Mepivacaine*
(Carbocaine)
Anesthetic drugs
4. Anesthesia for Ophthalmic Surgery
dr. Frenky
Anesthesia routes
1. Sub-tenon route
2. Retrobulbar route
3. Peribulbar route
5. Anesthesia for Ophthalmic Surgery
dr. Frenky
AIM:
• Provides akinesia and anesthesia to the
globe.
• Injection Subtenon space.
SITE OF INJECTION:
• The commonest approach is by the
inferonasal quadrant or
inferitemporal.
POSITION OF PATIENT:
• Supine in primary gaze.
L/A AGENTS:
• Lignocaine 2%
• Bupivacaine 0.75%
Along with:
• Hyaluronide: 3-7 UI/ml.
• Adrenaline: 1:200,000.
TECHNIQUE:
• Using 21G Rycroft cannula.
• The eye is cleaned and the patient asked
to look upwards and outwards.
• The conjunctiva is anesthetized first with
drops of the local anesthetic of choice.
Parabulbar/Sub-tenon’s Block
6. Anesthesia for Ophthalmic Surgery
dr. Frenky
Techniques…
Step 1:
Grab conjunctiva
and Tenon’s capsule
with Colibri forceps.
• Small cut with
Wetscot Schissors.
• Button hole
formed 5-10mm
from the limbus.
Step 2:
• Blunt curve’s
posterior sub-
tenon’s cannula with
local anesthesia.
• Move along the
curvature of the
sclera
Step 3:
Inject anesthetic
agent into sub-
tenon space.
Step 4:
7. Anesthesia for Ophthalmic Surgery
dr. Frenky
Disadvantages
• Less painful.
• Better analgesia than topical
anesthesia.
• Complications rarely serious.
• No increase in IOP.
• Surgery can begin immediately lasts
for 60 min and supplemental
anesthetic agent can be given.
• The globe can be voluntarily moved
at the surgeon’s instruction.
• Low dose and low volume of
anesthetic agent are used.
• The local anesthetic agent must be
injected into the capsule - double
perforation of the capsule results in
anesthetic leaking out, which
decreases the effectiveness of the
block.
• Although it is an advantage that the
globe can be moves under
instruction, it is important the eye is
not moved at other times - the use
of stabilizing sutures is advised.
• Chemosis and subconjunctival.
Advantages
Parabulbar/Sub-tenon’s Block
8. Anesthesia for Ophthalmic Surgery
dr. Frenky
Complications
Subconjunctival swelling. Subconjunctival Hemorrhage.
9. Anesthesia for Ophthalmic Surgery
dr. Frenky
Peribulbar Block
AIM:
• Injection outside the muscle cone.
• Block the orbital nerve, including 4th CN.
• Provides akinesia and anesthesia to the
globe.
SITE OF INJECTION:
• Inferotemporal quadrant.
• At junction of lateral 1/3 and medial
2/3 of inferior orbital margin.
POSITION OF PATIENT:
• Supine in primary gaze.
L/A AGENTS:
• Lignocaine 2%
• Bupivacaine 0.75%
Along with:
• Hyaluronide: 3-7 UI/ml.
• Adrenaline: 1:200,000.
TECHNIQUE:
• Using 22G 35 mm.
• Palpate inferior orbital rim.
• Place needle perpendicular through skin.
• Located needle 1/3 distance from lateral
medial canthus.
• Place just superior to inferior orbital rim.
10. Anesthesia for Ophthalmic Surgery
dr. Frenky
Techniques…
TECHNIQUE:
• Using 22G 35 mm.
• Palpate inferior orbital rim.
• Place needle perpendicular through
skin.
• Located needle 1/3 distance from
lateral medial canthus.
• Place just superior to inferior orbital rim.
11. Anesthesia for Ophthalmic Surgery
dr. Frenky
Techniques
1st Injection:
• Place just superior to inferior orbital rim.
• Advance parallel to the orbital floor, perforating
septum.
• Hub of needle should not go to beyond inferior
orbital rim.
• Aspirate to avoid blood vessel.
• Inject 3ml of anesthetic solution.
• Apply pressure to prevent hemorrhage and facilitate
diffusion of anesthetic.
2nd Injection:
• Locate needle by supraorbital notch, place needle
just inferior to the superior orbital rim, advance
needle straight back.
• Inject 3ml of anesthetic.
12. Anesthesia for Ophthalmic Surgery
dr. Frenky
Disadvantages
• The risk is low. • The quality of akinesia and
anesthesia may not be as good as
with retrobulbar block.
• Often more than one injection is
required.
• Chemosis occurs in 80% of cases,
which make operating operating
condition difficult.
Advantages
Peribulbar Block
13. Anesthesia for Ophthalmic Surgery
dr. Frenky
Complications
• Lids trauma.
• Ptosis.
• Muscle damage.
• Globe penetration.
• Retrobulbar hemorrhage.
• Optic nerve damage.
• Brainstem anesthesia.
14. Anesthesia for Ophthalmic Surgery
dr. Frenky
Retrobulbar Block
AIM:
• Injected the muscle cone to block:
• Ciliary nerve and ganglion.
• 3rd, 4th, 6th CN before enter to posterior
intrazonal space.
• Provides akinesia and anesthesia to the
globe.
TECHNIQUE:
• Using 22G 35 mm.
• Palpate inferior orbital rim.
• Place needle perpendicular through skin.
• Located needle 1/3 distance from lateral
medial canthus.
• Place just superior to inferior orbital rim.
POSITION OF PATIENT:
• Supine in primary gaze.
SITE OF INJECTION:
• Inferotemporal quadrant.
• At junction of lateral 1/3 and medial 2/3 of
inferior orbital margin.
L/A AGENTS:
• Lignocaine 2%
• Bupivacaine 0.75%
Along with:
• Vasoconstrictor (Epinephrine).
15. Anesthesia for Ophthalmic Surgery
dr. Frenky
• Inject 0.5ml of solution s/c to reduce pain when orbital septum is pierced.
• Advance needle parallel to orbital floor perforating the septum.
• After equater of globe is passed, direct needle superonasally at 30 degree angle,
advance, piercing intermuscular septum and enter muscle cone.
• Inject 4-5ml of anesthetic.
Techniques…
16. Anesthesia for Ophthalmic Surgery
dr. Frenky
Disadvantages
• Reliable for producing excellent
anesthesia and akinesia.
• The onset is quicker than with
peribulbar (5 minutes).
• Low volumes of anesthetic, results
in a lower intraorbital tension and
less chemosis than with peribulbar
blocks.
• Loss of visual acuity occurs in a
greater number of patients
compared to peribulbar blocks,
though this can be volume
dependent.
• The main disadvantage is that the
complication rate is higher than for
peribulbar blocks – the reason for
the development of the peribulbar
block.
Advantages
Retrobulbar Block
17. Anesthesia for Ophthalmic Surgery
dr. Frenky
Complications
• Retrobulbar hemorrhage.
• Ocular perforation.
• Subaracnoid and intradural injection.
• Muscle complication: ptosis from elevator aponeurosis
dehiscence, entropion and diplopia following EOM injection.
• Oculocardiac reflex.
18. Anesthesia for Ophthalmic Surgery
dr. Frenky
Subconjunctival Block
AIM:
• Anterior segment is blocked but no
akinesia.
TECHNIQUE:
• Asepsia with Betadine.
• Apply anesthesia drop.
• Using 27G or 30G needle, even 26G
needle.
• Injected the block under the
conjunctiva.POSITION OF PATIENT:
• Supine in primary gaze.
SITE OF INJECTION:
• At posterior to phase incision/
perilimbal conjunctiva.
L/A AGENTS:
• Lignocaine 2%
• Bupivacaine 0.75%
19. Anesthesia for Ophthalmic Surgery
dr. Frenky
Disadvantages
• Cost effective.
• Not affected EOM.
• Visual acuity
• Avoidance of complications: Globe
rupture, nerve damage.
• No akinesia.
• Not suitable for extended surgery.
Advantages
Subconjunctiva Block