Anesthesia in
Ophthalmic Surgery
Panit Cherdchu
Ophthalmology department
Phramongkutklao Hospital
OUTLINE
Review of Anatomy
Anesthetic Agents
Type of Anesthesia
Take Home Message
ORBITAL ANATOMY
measurement
“The orbital entrance
averages approximately 35
mm in height and 45 mm in
width”
“depth varies from 40-45 mm
from the orbital entrance to
the orbital apex”
7 BONES
Superior orbital fissure
Inferior orbital fissure
Optic canal
Infraorbital foramen
Frontal Ethmoidal
Maxillary Sphenoidal
Periorbital Sinuses
Ciliary Ganglion
• A long sensory
root
• A short motor
root
• A sympathetic
root
EOMExtraocular muscles
MUSCLES
• 4 Rectus: SR-IR-LR-MR
• 2 Oblique: SO-IO
• 1 Protractor: Orbicularis Oculi Muscle
• 1 Retractor: Levator Palpebral Superioris Muscle-
Muller’s muscle
“The relationship between the muscle insertions and
the ora serrata is clinically important. A misdirected
suture passed through the insertion of the superior
rectus muscle could perforate the retina”
Levator is
innervated by
CN III
1. skin
2. eyelid margin
3. subcutaneous connective tissue
4. orbicularis oculi muscle
5. orbital septum
6. levator palpebrae superioris muscle
7. Müller muscle
8. tarsus
9. conjunctiva
3 parts of orbicularis
oculi muscles
“The Tenon capsule (the fascia bulbi) is an envelope of elastic
connective tissue that fuses posteriorly with the optic nerve sheath
and anteriorly with a thin layer of tissue called the intermuscular
septum, which is located 3 mm posterior to the limbus”
Vascular Supply and Drainage of the Orbit
Vascular Supply and Drainage of the Orbit
Internal carotid artery and external
carotid artery collateral anatomy
• 1, internal carotid;
• 2, external carotid;
• 3, facial;
• 4, maxillary;
• 5, superficial temporal;
• 6, transverse facial;
• 7, middle meningeal;
• 8, frontal branch of superficial temporal;
• 9, ophthalmic;
• 10, lacrimal;
• 11, recurrent meningeal;
• 12, supraorbital;
• 13, supratrochlear;
• 14, angular;
• 15, palpebral;
• 16, zygomaticotemporal;
• 17, zygomaticofacial;
• 18, deep temporal;
• 19, infraorbital;
• 20, muscular.
3 main outlets of venous system
– Superior and inferior ophthalmic v. cavernous
sinus&cranial system
– Anastomosis of the ophthalmic v.&angular v.
facial venous system
– Inferior orbital fissure pterygoid venous plexus
NEUROANATOMY
• Cranial Nerve II
• Cranial Nerve III
• Cranial Nerve IV
• Cranial Nerve V
• Cranial Nerve VI
• Ciliary Ganglion
NEUROANATOMY
MOTOR NERVE
Local Anesthetic Agents
“The local anesthetic drugs used in
ophthalmology are tertiary amines linked by
either ester or amide bonds to an aromatic
residue”
“Protonated form(inside myelin sheath) blocks
the sodium channels on the inner wall of the cell
membrane and increases the threshold for
electrical excitability. As increasing numbers of
sodium channels are blocked, nerve conduction
is impeded and finally blocked”
• block the poorly myelinated and narrow
parasym&sym fibers
• Optic nerve is usually not impeded by retrobulbar
block
• Myelinated motor fibers (akinesia)
• Sensory fibers (pain+temp)
TOXIC
• The toxic manifestations of local anesthetics
are generally related to dose
• severe hepatic insufficiency
• even at lower doses. These manifestations
include restlessness and tremor that may
proceed to convulsions, and respiratory and
myocardial depression
EPINEPHRINE
• local anesthetics block sympathetic vascular
tone and dilate vessels,
• a 1:200,000 concentration of epinephrine is
frequently added to shorter-acting drugs to
retard vascular absorption
LIDOCAINE
• Lidocaine is an amide local anesthetic used in
strengths of 0.5%, 1%, and 2% (with or
without epinephrine) for injection
• It yields a rapid (5-minute) retrobulbar or
eyelid block that lasts 1–2 hours.
MEPIVACAINE
• Mepivacaine is an amide drug used in
strengths of 1%–3% (with or without a
vasoconstrictor).
• rapid onset and lasts approximately 2–3
hours. The maximum safe dose is 25 mL of a
2% solution.
BUPIVACAINE
• poor akinesia but has the advantage of a long
duration of action, up to 8 hours.
• mixture with lidocaine or mepivacaine to
achieve a rapid, complete, and long-lasting
effect.
• The maximum safe dose is 25 mL of a 0.75%
solution.
HYALURONIDASE
• combined with local injection of anesthetics to
increase the dispersion of the anesthetic drug
• More dispersion reduce the pressure rise in
the limited orbital space, produce less
distortion of the surgical site, decrease the risk
of postoperative strabismus and myotoxicity,
and increase akinesia of the globe and lid
HYALURONIDASE
• lower volumes of anesthetic agent.
• For retrobulbar or peribulbar injection, 1 mL
of hyaluronidase can be added to a syringe of
the anesthetic to be administered.
Type of Anesthesia
FACIAL NERVE BLOCK
LOCAL
ANESTHESIA
Topical Anesthetic Block
Subconjunctival Block
Intracameral Block
GENERAL
ANESTHESIA
REGIONAL
ANESTHESIA
Peribulbar Block
Parabulbar Block
Retrobulbar Block
LOCAL ANESTHESIA
• Topical Anesthesia Block
– Block superficial cornea and conjunctiva
– Block long and short ciliary nerve, nasociliary
nerve, lacrimal nerve
– Disrupt intercellular tight junction
LOCAL ANESTHESIA
• Subconjunctival block
– Anterior segment is blocked but no akinesia
– At posterior to phaco incision/ perilimbal
conjunctiva
LOCAL ANESTHESIA
• Intracameral block
– Anesthetic agent: 0.2-0.5 ml of unpreserved 1%
lidocaine hydrochloride
– If absence of posterior capsulemight cause
transient retinal toxicity “Transient Amaurosis”
Regional anesthesia
• Parabulbar block (sub-tenon block)
– Inferonasal, inferotemporal
– Inject anesthetic agent into sub-tenon space
– Patient look upward+outward
– Drug : 2% lidocaine, +hyaluronidase
Method
– Grab conjunctiva+Tenon’s capsule with blunt non-
toothed forceps
– Small cut with westcott scissors
– Blunt curved posterior sub-tenon’s cannula with
local anesthetic
– Move along the curvature of the sclera
– Inject anesthetic agent into sub-tenon space
move along the
curvature
BLUNT curved
• Expected outcome
– Akinesia
– Mydriasis
– Analgesia
– Hypotonia of lidsptosis
Button hole formed ~10 mm from the
corneal limbus
Freeing the Quadrant
Lacrimal cannular
Insertion of cannula and injection of
anesthetic.
• Still!!
– Superonasal block is indicated as supplementary
block
– Locate the needle at upper eyelid vertically above
the medial limbus
– Intermittent of ocular compression (10-
20minutes)
Pros cons
Reduce retrobulbar
hemorrhage accident
Might not achieve at
akinesis effect
Reduce risk of injury at
globe or optic nerve
Larger volume is needed
Reduce risk of intradural
injection
More incidence of
periorbital
ecchymosis+chemosis
Regional anesthesia
• Peribulbar block (Extraconal block)
– Inject into extraconal spacedrug spread to
whole area including intraconal area
– The larger space to apply, the more volume of
drug is needed.
Method
– Patients lies in supine + neutral position
– ¾ inch, 24-26G needle
– Anesthetic agent: 5ml of 0.75%bupivacaine// 5 ml
of 2%lidocaine with 1:200,000 adrenaline//150
units of hyaluronidase
Method
– Point at lateral1/3 and the medial 2/3 of the
inferior orbital edge
– Directed to the apex of the orbit
– at equator of globe
• Retrobulbar block (intraconal block)
– 25G, 1 ½ inches needle
– Neutral position
– Point at lateral 1/3 and medial 2/3 of inferior orbital
edge
– Posteriorly parallel to the orbital floor, incline of 15
degree
– Pass equatorshift to medially and superiorly angle
of 45 degree
– Depth 25-35 mm
– Compress for 15 sec on5 sec off for 1-2 minutes
Regional anesthesia
• Akinesia and Anesthesia are quickly ensure
the complete block
Retrobulbar Block - Step 1
• Enter just inferior to the globe and
perpendicular to the plane of the face.
Retrobulbar Block - Step 2
• Once you feel the first pop through the orbital
septum, angle 45 degrees medially and 45
degrees superiorly towards the apex of the
orbit until the second pop through the muscle
cone is felt.
Retrobulbar Block - Injection
Pull back on the syringe to ensure the needle is
not in a vessel, then inject 3-5 cc of anesthetic,
palpating the globe to assess for posterior
pressure
Pros Cons
Low volume of drug Risk of retrobulbar
hemorrhage
High potency of blocking Oculocardiac reflex
Rapid onset CRAO
Puncture into globe,optic
nerve
Risk of brain stem
anesthesia
Epinephrine toxicity
Retrobulbar hemorrhage
• increasing proptosis with tight eyelids,
subconjunctival and periorbital haemorrhage,
and a dramatic increase in intraorbital
pressure
Lateral Canthotomy
Oculocardiac reflex
• rapid distension of the tissues by volume or
haemorrhage provoke it occasionally
• Bradycardia, Junctional Rhythm, Asystole
Central Retinal Artery Occlusion
• Sudden, complete, and painless loss of vision
• Must!! immediately reduce the IOP
Puncture into globe
• myopic eyes which are longer but also thinner
• globes longer than 26 mm are at risk
• A diagnosis of perforation may be made by
pain at the time the block is performed,
sudden loss of vision, hypotonia, a poor red
reflex or vitreous haemorrhage
Puncture into optic nerve
Brainstem Anesthesia
• Onset can be 2-40 minutes after injection
• symptoms are drowsiness, vomiting,
contralateral blindness caused by reflux of the
drug to the optic chiasm, convulsions,
respiratory depression or arrest, neurological
deficit, cardiac arrest
Brainstem Anesthesia
FacialNerveBlock
Van Lint Method
• 1 cm below and
behind the
lateral canthus
O’Brien’s Method
• The
condyloid
process of
the
mandible
Atkinson Method
• At Inferior edge of
the zygomatic
bone
Nadbath Ellis Method
Where facial nerve
first emerges from
stylomastoid
foramen
THE END

Anesthesia in ophthalmic surgery

  • 1.
    Anesthesia in Ophthalmic Surgery PanitCherdchu Ophthalmology department Phramongkutklao Hospital
  • 2.
    OUTLINE Review of Anatomy AnestheticAgents Type of Anesthesia Take Home Message
  • 3.
  • 4.
    measurement “The orbital entrance averagesapproximately 35 mm in height and 45 mm in width” “depth varies from 40-45 mm from the orbital entrance to the orbital apex”
  • 5.
  • 6.
    Superior orbital fissure Inferiororbital fissure Optic canal Infraorbital foramen
  • 9.
  • 10.
    Ciliary Ganglion • Along sensory root • A short motor root • A sympathetic root
  • 11.
  • 12.
    MUSCLES • 4 Rectus:SR-IR-LR-MR • 2 Oblique: SO-IO • 1 Protractor: Orbicularis Oculi Muscle • 1 Retractor: Levator Palpebral Superioris Muscle- Muller’s muscle
  • 13.
    “The relationship betweenthe muscle insertions and the ora serrata is clinically important. A misdirected suture passed through the insertion of the superior rectus muscle could perforate the retina”
  • 14.
    Levator is innervated by CNIII 1. skin 2. eyelid margin 3. subcutaneous connective tissue 4. orbicularis oculi muscle 5. orbital septum 6. levator palpebrae superioris muscle 7. Müller muscle 8. tarsus 9. conjunctiva
  • 15.
    3 parts oforbicularis oculi muscles
  • 16.
    “The Tenon capsule(the fascia bulbi) is an envelope of elastic connective tissue that fuses posteriorly with the optic nerve sheath and anteriorly with a thin layer of tissue called the intermuscular septum, which is located 3 mm posterior to the limbus”
  • 17.
    Vascular Supply andDrainage of the Orbit Vascular Supply and Drainage of the Orbit
  • 20.
    Internal carotid arteryand external carotid artery collateral anatomy • 1, internal carotid; • 2, external carotid; • 3, facial; • 4, maxillary; • 5, superficial temporal; • 6, transverse facial; • 7, middle meningeal; • 8, frontal branch of superficial temporal; • 9, ophthalmic; • 10, lacrimal; • 11, recurrent meningeal; • 12, supraorbital; • 13, supratrochlear; • 14, angular; • 15, palpebral; • 16, zygomaticotemporal; • 17, zygomaticofacial; • 18, deep temporal; • 19, infraorbital; • 20, muscular.
  • 21.
    3 main outletsof venous system – Superior and inferior ophthalmic v. cavernous sinus&cranial system – Anastomosis of the ophthalmic v.&angular v. facial venous system – Inferior orbital fissure pterygoid venous plexus
  • 24.
    NEUROANATOMY • Cranial NerveII • Cranial Nerve III • Cranial Nerve IV • Cranial Nerve V • Cranial Nerve VI • Ciliary Ganglion NEUROANATOMY
  • 25.
  • 29.
  • 30.
    “The local anestheticdrugs used in ophthalmology are tertiary amines linked by either ester or amide bonds to an aromatic residue”
  • 31.
    “Protonated form(inside myelinsheath) blocks the sodium channels on the inner wall of the cell membrane and increases the threshold for electrical excitability. As increasing numbers of sodium channels are blocked, nerve conduction is impeded and finally blocked”
  • 32.
    • block thepoorly myelinated and narrow parasym&sym fibers • Optic nerve is usually not impeded by retrobulbar block • Myelinated motor fibers (akinesia) • Sensory fibers (pain+temp)
  • 35.
    TOXIC • The toxicmanifestations of local anesthetics are generally related to dose • severe hepatic insufficiency • even at lower doses. These manifestations include restlessness and tremor that may proceed to convulsions, and respiratory and myocardial depression
  • 36.
    EPINEPHRINE • local anestheticsblock sympathetic vascular tone and dilate vessels, • a 1:200,000 concentration of epinephrine is frequently added to shorter-acting drugs to retard vascular absorption
  • 37.
    LIDOCAINE • Lidocaine isan amide local anesthetic used in strengths of 0.5%, 1%, and 2% (with or without epinephrine) for injection • It yields a rapid (5-minute) retrobulbar or eyelid block that lasts 1–2 hours.
  • 38.
    MEPIVACAINE • Mepivacaine isan amide drug used in strengths of 1%–3% (with or without a vasoconstrictor). • rapid onset and lasts approximately 2–3 hours. The maximum safe dose is 25 mL of a 2% solution.
  • 39.
    BUPIVACAINE • poor akinesiabut has the advantage of a long duration of action, up to 8 hours. • mixture with lidocaine or mepivacaine to achieve a rapid, complete, and long-lasting effect. • The maximum safe dose is 25 mL of a 0.75% solution.
  • 40.
    HYALURONIDASE • combined withlocal injection of anesthetics to increase the dispersion of the anesthetic drug • More dispersion reduce the pressure rise in the limited orbital space, produce less distortion of the surgical site, decrease the risk of postoperative strabismus and myotoxicity, and increase akinesia of the globe and lid
  • 41.
    HYALURONIDASE • lower volumesof anesthetic agent. • For retrobulbar or peribulbar injection, 1 mL of hyaluronidase can be added to a syringe of the anesthetic to be administered.
  • 42.
  • 43.
    FACIAL NERVE BLOCK LOCAL ANESTHESIA TopicalAnesthetic Block Subconjunctival Block Intracameral Block GENERAL ANESTHESIA REGIONAL ANESTHESIA Peribulbar Block Parabulbar Block Retrobulbar Block
  • 44.
    LOCAL ANESTHESIA • TopicalAnesthesia Block – Block superficial cornea and conjunctiva – Block long and short ciliary nerve, nasociliary nerve, lacrimal nerve – Disrupt intercellular tight junction
  • 45.
    LOCAL ANESTHESIA • Subconjunctivalblock – Anterior segment is blocked but no akinesia – At posterior to phaco incision/ perilimbal conjunctiva
  • 46.
    LOCAL ANESTHESIA • Intracameralblock – Anesthetic agent: 0.2-0.5 ml of unpreserved 1% lidocaine hydrochloride – If absence of posterior capsulemight cause transient retinal toxicity “Transient Amaurosis”
  • 47.
    Regional anesthesia • Parabulbarblock (sub-tenon block) – Inferonasal, inferotemporal – Inject anesthetic agent into sub-tenon space – Patient look upward+outward – Drug : 2% lidocaine, +hyaluronidase
  • 48.
    Method – Grab conjunctiva+Tenon’scapsule with blunt non- toothed forceps – Small cut with westcott scissors – Blunt curved posterior sub-tenon’s cannula with local anesthetic – Move along the curvature of the sclera – Inject anesthetic agent into sub-tenon space
  • 49.
  • 50.
    • Expected outcome –Akinesia – Mydriasis – Analgesia – Hypotonia of lidsptosis
  • 51.
    Button hole formed~10 mm from the corneal limbus
  • 52.
  • 53.
  • 54.
    Insertion of cannulaand injection of anesthetic.
  • 55.
    • Still!! – Superonasalblock is indicated as supplementary block – Locate the needle at upper eyelid vertically above the medial limbus – Intermittent of ocular compression (10- 20minutes)
  • 56.
    Pros cons Reduce retrobulbar hemorrhageaccident Might not achieve at akinesis effect Reduce risk of injury at globe or optic nerve Larger volume is needed Reduce risk of intradural injection More incidence of periorbital ecchymosis+chemosis
  • 57.
    Regional anesthesia • Peribulbarblock (Extraconal block) – Inject into extraconal spacedrug spread to whole area including intraconal area – The larger space to apply, the more volume of drug is needed.
  • 58.
    Method – Patients liesin supine + neutral position – ¾ inch, 24-26G needle – Anesthetic agent: 5ml of 0.75%bupivacaine// 5 ml of 2%lidocaine with 1:200,000 adrenaline//150 units of hyaluronidase
  • 59.
    Method – Point atlateral1/3 and the medial 2/3 of the inferior orbital edge – Directed to the apex of the orbit – at equator of globe
  • 60.
    • Retrobulbar block(intraconal block) – 25G, 1 ½ inches needle – Neutral position – Point at lateral 1/3 and medial 2/3 of inferior orbital edge – Posteriorly parallel to the orbital floor, incline of 15 degree – Pass equatorshift to medially and superiorly angle of 45 degree – Depth 25-35 mm – Compress for 15 sec on5 sec off for 1-2 minutes Regional anesthesia
  • 61.
    • Akinesia andAnesthesia are quickly ensure the complete block
  • 62.
    Retrobulbar Block -Step 1 • Enter just inferior to the globe and perpendicular to the plane of the face.
  • 63.
    Retrobulbar Block -Step 2 • Once you feel the first pop through the orbital septum, angle 45 degrees medially and 45 degrees superiorly towards the apex of the orbit until the second pop through the muscle cone is felt.
  • 64.
    Retrobulbar Block -Injection Pull back on the syringe to ensure the needle is not in a vessel, then inject 3-5 cc of anesthetic, palpating the globe to assess for posterior pressure
  • 65.
    Pros Cons Low volumeof drug Risk of retrobulbar hemorrhage High potency of blocking Oculocardiac reflex Rapid onset CRAO Puncture into globe,optic nerve Risk of brain stem anesthesia Epinephrine toxicity
  • 66.
  • 67.
    • increasing proptosiswith tight eyelids, subconjunctival and periorbital haemorrhage, and a dramatic increase in intraorbital pressure
  • 68.
  • 69.
    Oculocardiac reflex • rapiddistension of the tissues by volume or haemorrhage provoke it occasionally • Bradycardia, Junctional Rhythm, Asystole
  • 70.
    Central Retinal ArteryOcclusion • Sudden, complete, and painless loss of vision • Must!! immediately reduce the IOP
  • 71.
    Puncture into globe •myopic eyes which are longer but also thinner • globes longer than 26 mm are at risk • A diagnosis of perforation may be made by pain at the time the block is performed, sudden loss of vision, hypotonia, a poor red reflex or vitreous haemorrhage
  • 73.
  • 74.
    Brainstem Anesthesia • Onsetcan be 2-40 minutes after injection • symptoms are drowsiness, vomiting, contralateral blindness caused by reflux of the drug to the optic chiasm, convulsions, respiratory depression or arrest, neurological deficit, cardiac arrest
  • 75.
  • 76.
  • 77.
    Van Lint Method •1 cm below and behind the lateral canthus
  • 78.
  • 79.
    Atkinson Method • AtInferior edge of the zygomatic bone
  • 80.
    Nadbath Ellis Method Wherefacial nerve first emerges from stylomastoid foramen
  • 81.