The document discusses the anatomy of the larynx. It describes the cartilages that make up the larynx, including the thyroid, cricoid, epiglottis, and others. It discusses the joints and membranes in the larynx. It also summarizes the intrinsic and extrinsic muscles that control the larynx, as well as the blood supply, nerve supply, and embryonic development of the larynx.
The larynx houses the vocal cords, and manipulates pitch and volume, which is essential for phonation. It is situated just below where the tract of the pharynx splits into the trachea and the esophagus.
The larynx houses the vocal cords, and manipulates pitch and volume, which is essential for phonation. It is situated just below where the tract of the pharynx splits into the trachea and the esophagus.
The pharynx is a hollow tube that starts behind the nose, goes down the neck, and ends at the top of the trachea and esophagus. The three parts of the pharynx are the nasopharynx, oropharynx, and hypopharynx.
The pharynx is a hollow tube that starts behind the nose, goes down the neck, and ends at the top of the trachea and esophagus. The three parts of the pharynx are the nasopharynx, oropharynx, and hypopharynx.
It is just a concise presentation about anatomy of larynx & TB tree. little bit about anaesthetic consideration regarding vocalcordpalsy and aspiration pneumonitis.
Anatomy and physiology of larynx presentation for MBBS 3rd year. This ppt presents the most detailed presentation of anatomy and physiology of larynx. Presenter was third year MBBS students of Nepalgunj Medical College and teaching hospital, Nepalgunj Nepal. Niraj Prasad Sah won the best presentation award for this during ENT posting. Have fun and check this out.
Larynx (Human Anatomy) Medical PresentationSyed Mohammad
Its about anatomy of Larynx (Introduction, Location, Size, Relation, Structures, Cartilage, Membrane and Ligaments, Laryngeal Cavity, Muscles, Vocal Code, sphincter, Blood supply, lymphatic drainage,nerve supply, production of Voice, clinical anatomy
This is a presentation I used for my seminar on 'Phonosurgery' on 4th November, 2015. I hope they are useful to you. Constructive as well as Destructive criticism welcomed.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. Also called ‘voice box’
Lies in front of hypopharynx
Opposite the C3-C6 vertebrae
It moves vertically and in AP direction during
swallowing and phonation
Laryngeal crepitus: Passive movement of
larynx from side to side producing a grating
sensation
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4. Thyroid cartilage (Hyaline)
Largest of all
Two alae meet anteriorly to form an angle of
90º in in males and 120º in females
Vocal cords are attached to the middle of
thyroid angle
Most of the FBs are arrested above the vocal
cords, hence cricothyrotomy secures airway
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5. Cricoid cartilage (Hyaline)
Only cartilage forming a complete ring
Anterior narrow part is arch
Posterior expanded part is lamina
Epiglottis (Fibroelastic)
Leaf like, yellow, elastic cartilage
Fat in the anterior surface (pre epiglottic
space). This space can be invaded by
supraglottic CA or CA BOT
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6. Arytenoid cartilages (mostly hyaline)
Pyramidal in shape
Base: articulates with cricoid cartilage
Lateral muscular process: For intrinsic
muscles of larynx
Anterior vocal process: For vocal cord
Apex: Supports the corniculate cartilage
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7. Corniculate cartilages (of Santorini)
Fibroelastic
Each articulates with apex of arytenoid
cartilage
Cuneiform cartilages (of Wrisberg)
Fibroelastic
Rod shaped
Situated in aryepiglottic fold
Provide passive support to the fold
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9. Criciarytenoid joint
- Synovial
- Rotatory movement (adduction & abduction
of VC)
- Gliding movement (closing & opening the
posterior part of glottis)
Cricithyroid joint
- Synovial
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10. Extrinsic membranes
- Thyrohyoid membrane: Pierced by superior
laryngeal vessels & internal laryngeal nerve
- Cricothyroid membrane
- Cricotracheal membrane
Intrinsic membranes
- Cricovocal membrane: Its upper free border
forms vocal ligament (true vocal cord). It forms
conus elasticus (subglottic FBs lodge here)
- Quadrangular membrane: Its lower border
forms vestibular ligament (false vocal cord)
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11. Intrinsic Muscles (b/w laryngeal cartilages)
(a) Those acting on VC
- Abductors: Posterior criciarytenoid
- Adductors: Lateral cricoarytenoid
Interarytenoid (transverse)
Thyroarytenoid (external part)
- Tensors: Cricothyroid
Vocalis (internal part of
thyroarytenoid)
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12. (b) Those acting on laryngeal inlet
- Openers of inlet
Thyroepiglottic (part of thyroarytenoid)
- Closers of inlet
Interarytenoid (oblique part)
Aryepiglottic
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16. From laryngeal inlet to lower border of cricoid
cartilage
3 parts: Vestibule, Ventricle & Subglottic
space
- Vestibule: From laryngeal inlet to vestibular
folds
- Ventricle (sinus of larynx): B/w vestibular and
vocal folds. Saccule is a diverticulum of
mucus membrane (Laryngocele)
- Subglottic space: From VC to lower border of
cricoid cartilage
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20. Supraglottic: Pierce the throhyoid membrane
& drain into upper deep cervical
Infraglottic: Pierce the cricothyroid membrane
& drain into prelaryngeal & pretracheal nodes
Glottic: No lymphatics
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21. Motor: RLN (except cricothyroid, which is
supplied by external laryngeal nerve, branch
of SLN)
Sensory
- Above VC: Internal laryngeal nerve (SLN)
- Below VC: RLN
RLN arises from vagus. Left RLN has a longer
course (it arises in mediastinum), so more
prone to paralysis
SLN arises from inferior ganglion
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23. Pre-epiglottic space of Boyer
- Filled with fat
- Continuous laterally with paraglottic space
Paraglottic space
- Growths which invade this space can
present in the neck through cricothyroid
space
Reinke’s space
- Under the epithelium of VC
- Reinke’s edema: fusiform swelling of
membranous cords
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24. Epiglottis: Hypobranchial eminence
Upper part of thyroid cartilage: 4th Arch (SLN)
Lower part of thyroid cartilage
Cricoid/Corniculate/Cuneiform 6th Arch
Intrinsic muscles of larynx (RLN)
Upper part of body & lesser cornu
of hyoid 2nd Arch
Stylohyoid ligament
Lower part of body and greater cornu of
hyoid: 3rd Arch
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25. Positioned high at C3 or C4 at rest and
reaches C1 or C2 during swallowing
Laryngeal cartilages are soft & collapse easily
Epiglottis in omega shaped
Thyroid cartilage is flat
Larynx is small & conical (subglottis is
narrowest)
Submucosal tissues are loose
VC is 6 mm in females, 8 mm in males
(children), 15-19 mm in females & 17-23
mm in males (adults)
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