This document describes the design, synthesis, and evaluation of benzimidazolo/tetrazolo quinazoline compounds. Specifically, it details the reaction of anthranilic acid with primary amides to form quinazolinones, which were then treated with phosphorus oxychloride and phosphorus pentachloride to form chloroquinazolines. These compounds then reacted with o-phenylenediamine or sodium azide to form the target benzimidazolo or tetrazolo quinazolines. The compounds were evaluated for their antihyperglycemic activity in sucrose-loaded rat models, with the benzimidazolo quinazolines showing better but still low activity