Allergic rhinitis is a common chronic inflammatory disease of the nasal mucosa affecting 10-20% of the population. It is caused by an IgE-mediated response to airborne allergens like dust mites, pollen, and animal dander. Symptoms include rhinorrhea, nasal congestion, sneezing, and itching. Allergic rhinitis is classified based on symptom duration and severity. Treatment involves avoidance of triggers, oral antihistamines, intranasal corticosteroids, and immunotherapy to relieve symptoms and inflammation. Allergic rhinitis and asthma often co-exist as part of a combined airway inflammatory disease.
Part 1 of Asthama Lecture for Final Year MBBS students
Definition, Pathophysiology, Pathology, History, Symptoms, Signs , Investigation. also see Part2
Asthma in children & Infants: Symptoms and TreatmentEPIC Health
Asthma affects over 7 million children in the U.S, which is about 8.5% of the child population, making it one of the most common pediatric illnesses in the country.
Part 1 of Asthama Lecture for Final Year MBBS students
Definition, Pathophysiology, Pathology, History, Symptoms, Signs , Investigation. also see Part2
Asthma in children & Infants: Symptoms and TreatmentEPIC Health
Asthma affects over 7 million children in the U.S, which is about 8.5% of the child population, making it one of the most common pediatric illnesses in the country.
Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the Cysteinyl leukotriene CysLT1 receptor. Each 10 mg film-coated Loctril tablet contains 10.4 mg Montelukast sodium, which is equivalent to 10 mg of Montelukast.
Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the Cysteinyl leukotriene CysLT1 receptor. Each 10 mg film-coated Loctril tablet contains 10.4 mg Montelukast sodium, which is equivalent to 10 mg of Montelukast.
Introduction to InSpec and 1.0 release updateAlex Pop
Contains an introduction to infrastructure and compliance tests as code and how InSpec can be used for this.
Agenda:
* Why infrastructure tests as code
* What is InSpec and how it works
* Core and custom resources
* What's new in InSpec 1.0 (released Sept 26, 2016)
* Documentation and installation
* Integrations
* Demo
* Chef Community Summit
Описание и структурирование бизнес-процессов в компании при внедрении корпор...Виктор Степанов
- Почему нужно описывать бизнес-процессы до автоматизации.
- Общие принципы описания бизнес-процессов.
- Как соблюсти баланс гибкости и регламентации.
- Как организовать проект внедрения информационной системы.
- Дальнейшее развитие и поддержка системы.
- Роль консультантов по управлению в проекте внедрения информационной системы.
The Future of Allergy and Clinical Immunology Prof. G. Walter Canonica - Con...Juan Carlos Ivancevich
Prof.G.Walter Canonica
Allergy and Respiratory Diseases Clinic
DIMI-‐University of Genoa
Italy
Presidente Congreso SLaai 2015: Dr. Alfonso Cepeda Sarabia
Chất lượng sống không còn được đảm bảo, môi trường ngày càng ô nhiễm, thời tiết thất thường, chính những yếu tố khách quan này khiến căn bệnh viêm mũi dị ứng ngày càng phổ biến trong cộng đồng. Vậy chúng ta cần làm gì để phòng tránh? Căn bệnh viêm mũi dị ứng nguy hiểm như thế nào? Cùng chúng tôi tìm hiểu về căn bệnh này ngay sau đây!
Nguồn: Trích https://venusglobal.com.vn/viem-mui-di-ung/
#viêm_mũi_dị_ứng
#viêm_mũi_họng_dị_ứng
#viêm_mũi_dị_ứng_là_gì
#triệu_chứng_viêm_mũi_dị_ứng
#bị_viêm_mũi_dị_ứng
#triệu_chứng_của_viêm_mũi_dị_ứng
Allergic rhinitis is a very common disorder that affects people of all ages. It is frequently ignored, under diagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Although allergic rhinitis is not a serious illness, it is clinically relevant because it underlies many complications, is a major risk factor for poor asthma control, and affects quality of life and productivity at work or school. Hidden direct costs include the treatment of co-morbid asthma, chronic sinusitis, otitis media, upper respiratory infection, and nasal polyp. Nasal congestion, the most prominent symptom in AR, is associated with sleep-disordered breathing, a condition that can have a profound effect on mental health, including increased psychiatric disorders, depression, anxiety, and alcohol abuse. Furthermore, sleep-disordered breathing in childhood and adolescence is associated with increased disorders of learning performance, behavior, and attention. Management of allergic rhinitis is best when directed by guidelines. At this juncture Homoeopathic system of medicine offers a safe and effective solution of the illness if followed under the guidance of expertise. This article provides an overview of the patho-physiology, diagnosis, and appropriate homoeopathic management of this disorder.
Dr. Smita Brahmachari
M.O., Dept. of AYUSH, Govt. of NCT Delhi.
Allergic rhinitis (AR) is an atopic disease presenting with symptoms of sneezing, nasal congestion, clear rhinorrhea, and nasal pruritis. It is an IgE-mediated immune response that is against inhaled antigens in the immediate phase, with a subsequent leukotriene-mediated late phase
Best Ayurvedic medicine for Gas and IndigestionSwastikAyurveda
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
3. Delayed-Reaction Allergy
Delayed-reaction allergy is caused by activated T cells and not by
antibodies.
In the case of poison ivy, the toxin of poison ivy in itself does not
cause much harm to the tissues. However, on repeated exposure, it
does cause the formation of activated helper and cytotoxic T cells.
Then, after subsequent exposure to the poison ivy toxin, within a day
or so, the activated T cells diffuse from the circulating blood in large
numbers into the skin to respond to the poison ivy toxin.
The damage normally occurs in the tissue area where the instigating
antigen is present, such as in the skin in the case of poison ivy, or in
the lungs to cause lung edema or asthmatic attacks in the case of
some airborne antigens.
4. Allergic PersonThe allergic tendency is genetically passed from parent to child
and is characterized by the presence of large quantities of IgE
antibodies in the blood.
These antibodies are called reagins or sensitizing antibodies to
distinguish them from the more common IgG antibodies.
When an allergen (defined as an antigen that reacts
specifically with a specific type of IgE reagin antibody) enters
the body, an allergen-reagin reaction takes place and a
subsequent allergic reaction occurs.
A special characteristic of the IgE antibodies (the reagins) is a
strong propensity to attach to mast cells and basophils.
5. Allergic PersonAt any rate, many of the mast cells and basophils rupture;
others release special agents immediately or shortly
thereafter, including histamine, protease, slowreacting
substance of anaphylaxis (which is a mixture of toxic
leukotrienes), eosinophil chemotactic substance, neutrophil
chemotactic substance, heparin, and platelet activating
factors.
These substances cause such effects as dilation of the local
blood vessels; attraction of eosinophils and neutrophils to the
reactive site; increased permeability of the capillaries with loss
of fluid into the tissues; and contraction of local smooth
muscle cells.
8. IntroductionRhinitis is broadly defined as inflammation of the nasal
mucosa.
Allergic rhinitis is the most common type of chronic rhinitis,
affecting 10 to 20% of the population, and evidence suggests
that the prevalence of the disorder is increasing.
In the past, allergic rhinitis was considered to be a disorder
localized to the nose and nasal passages, but current evidence
indicates that it may represent a component of systemic
airway disease involving the entire respiratory tract.
Allergic Rhinitis
9. IntroductionEvidence has shown that allergen provocation of the upper
airways not only leads to a local inflammatory response, but
also to inflammatory processes in the lower airways, and this
is supported by the fact that rhinitis and asthma frequently
coexist.
Therefore, allergic rhinitis and asthma appear to represent a
combined airway inflammatory disease, and this needs to be
considered to ensure the optimal assessment and
management of patients with allergic rhinitis.
Allergic Rhinitis
10. PathophysiologyIn allergic rhinitis, numerous inflammatory cells, including
mast cells, CD4-positive T cells, B cells, macrophages, and
eosinophils, infiltrate the nasal lining upon exposure to an
inciting allergen (most commonly airborne dust mite fecal
particles, cockroach residues, animal dander, moulds, and
pollens).
The T cells infiltrating the nasal mucosa are predominantly T
helper (Th) in nature and release cytokines (e.g., interleukin IL-
3, IL-4, IL-5, and IL-13) that promote immunoglobulin E (IgE)
production by plasma cells.
Allergic Rhinitis
11. PathophysiologyIgE production, in turn, triggers the release of mediators, such
as histamine and leukotrienes, that are responsible for
arteriolar dilation, increased vascular permeability, itching,
rhinorrhea (runny nose), mucous secretion, and smooth
muscle contraction.
The mediators and cytokines released during the early phase
of an immune response to an inciting allergen, trigger a
further cellular inflammatory response over the next 4 to 8
hours (late phase inflammatory response) which results in
recurrent symptoms (usually nasal congestion).
Allergic Rhinitis
12. ClassificationRhinitis is classified into one of the following categories
according to etiology:
IgE-mediated (allergic)
Autonomic
Infectious
Idiopathic (unknown)
Traditionally, allergic rhinitis has been categorized as seasonal
(occurs during a specific season) or perennial (occurs
throughout the year).
allergic rhinitis is now classified according to symptom
duration (intermittent or persistent) and severity (mild,
moderate or severe).
Allergic Rhinitis
13. ClassificationRhinitis is considered intermittent when the total duration of
the episode of inflammation is less than 6 weeks, and
persistent when symptoms continue throughout the year.
Symptoms are classified as mild when patients are generally
able to sleep normally and perform normal activities (including
work or school); mild symptoms are usually intermittent.
Symptoms are categorized as moderate/severe if they
significantly affect sleep and activities of daily living and/or if
they are considered bothersome.
Allergic Rhinitis
14. Etiological Classification
Allergic Rhinitis
ETIOLOGICAL CLASSIFICATION OF RHINITIS
Type Description
IgE-mediated (Allergic) IgE-mediated inflammation of the nasal mucosa, resulting in eosinophilic and Th2-
cell infiltration of the nasal lining
Further classified as intermittent or persistent
Autonomic Drug-induced (rhinitis medicamentosa)
Hypothyroidism
Hormonal
Non-allergic rhinitis with eosinophilia syndrome (NARES)
Infectious Precipitated by viral (most common), bacterial, or fungal infection
Idiopathic Etiology cannot be determined
15. Classification (symptoms, duration & severity)
INTERMITTENT:
Symptoms 6 weeks
PERSISTENT:
Symptoms continue throughout the year
MILD:
Normal Sleep
No impairment of daily activities, sport, leisure
Normal work/school
No bothersome symptoms
Allergic Rhinitis
16. Classification (symptoms, duration & severity)
MODERATE-SEVERE
Abnormal Sleep or
Impairment of daily activities, sport, leisure or
Problems at work/school or
Bothersome symptoms
Allergic Rhinitis
17. TreatmentThe treatment goal for allergic rhinitis is relief of symptoms.
Therapeutic options available to achieve this goal include
avoidance measures, oral antihistamines, intranasal
corticosteroids, leukotriene receptor antagonists, and allergen
immunotherapy.
Other therapies that may be useful in select patients include
decongestants and oral corticosteroids.
Allergic rhinitis and asthma appear to represent a combined
airway inflammatory disease and, therefore, treatment of
asthma is also an important consideration in patients with
allergic rhinitis.
Allergic Rhinitis
19. OVERVIEW OF PHARMACOLOGIC TREATMENT OPTIONS FOR ALLERGIC RHINITIS
Therapy Usual Adult Dose Usual Paediatric Dose
Oral Antihistamines (2nd Generation)
Cetirizine (Reactine) 5-10mg OD 5-10 ml (1-2 teaspoons) OD
(children’s formulation)
Desloratadine (Aerius) 5mg OD 2.5-5 ml (0.5-1.0 teaspoon) OD
(children’s formulation)
Fexofenadine (Allegra) 60mg BD or 120mg OD Not currently indicated for children
under 12 years of age
Loratadine (Claritin) 10mg OD 5-10 ml (1-2 teaspoons) OD
(children’s formulation)
Intranasal Corticosteroids
Beclomethasone (Beconase) 1-2 sprays (42 µg/spray) EN, BD 1 spray (42 μg/spray) EN, BD
Budesonide (Rhinocort) 2 sprays (64 µg/spray) EN, OD or 1
spray BD
2 sprays (64 μg/spray) EN, OD or 1
spray EN, BD (do not exceed 256 μg)
Ciclesonide (Omnaris) 2 sprays (50 µg/spray) EN, OD Not indicated for children under 12
years of age
Fluticasone Furoate (Avamys) 2 sprays (27.5 µg/spray) EN, OD 1 spray (27.5 μg/spray) EN, OD
Fluticasone Propionate (Flonase) 2 sprays (50 µg/spray) EN, OD or BD
(for severe rhinitis)
1-2 sprays (50 μg/spray) EN, OD
Mometasone Furoate (Nasonex) 2 sprays (50 µg/spray) EN, OD 1 spray (50 μg/spray) EN, OD
Triamcinolone Acetonide
(Nasacort)
2 sprays (55 µg/spray) EN, OD 1 spray (55 μg/spray) EN, OD
Leukotriene Receptor Antagonists
Montelukast (Singulair) 10mg OD Not currently approved for patients
under 15 years of age
Allergic Rhinitis