B.Pharm I Year II Sem. SN1 and SN2 reactions, kinetics, order of reactivity of alkyl halides, stereochemistry and rearrangement of carbocations.
SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions.
Structure and uses of ethylchloride, Chloroform, trichloroethylene, tetrachloroethylene,
dichloromethane, tetrachloromethane and iodoform.
Alcohols, Qualitative tests for Alcohol, Structure and uses of Ethyl alcohol, chlorobutanol, Cetosterylalcohol, Benzyl alcohol, Glycerol, Propylene glycol
Introduction to benzene, orbital picture, resonance in benzene, Huckel‟s rule
Reactions of benzene - nitration, sulphonation, halogenation- reactivity, Friedel- Craft‟s alkylation- reactivity, limitations, Friedel-Craft‟s acylation.
Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction.
In organic chemistry, a carbonyl group is a functional group composed of a carbon atom double-bonded to an oxygen atom: C=O. It is common to several classes of organic compounds, as part of many larger functional groups. A compound containing a carbonyl group is often referred to as a carbonyl compound.
Classification, Nomenclature and structural isomerism of organic compound Ganesh Mote
Classification of organic compound, Nomenclature of alkane, alkene, alkyne, alcohol, alkyl halide, aldehyde, ketone, carboxylic acid and its derivatives, amines, ethers, polyfunctional groups and structural isomerism of organic compounds
B.Pharm I Year II Sem. SN1 and SN2 reactions, kinetics, order of reactivity of alkyl halides, stereochemistry and rearrangement of carbocations.
SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions.
Structure and uses of ethylchloride, Chloroform, trichloroethylene, tetrachloroethylene,
dichloromethane, tetrachloromethane and iodoform.
Alcohols, Qualitative tests for Alcohol, Structure and uses of Ethyl alcohol, chlorobutanol, Cetosterylalcohol, Benzyl alcohol, Glycerol, Propylene glycol
Introduction to benzene, orbital picture, resonance in benzene, Huckel‟s rule
Reactions of benzene - nitration, sulphonation, halogenation- reactivity, Friedel- Craft‟s alkylation- reactivity, limitations, Friedel-Craft‟s acylation.
Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction.
In organic chemistry, a carbonyl group is a functional group composed of a carbon atom double-bonded to an oxygen atom: C=O. It is common to several classes of organic compounds, as part of many larger functional groups. A compound containing a carbonyl group is often referred to as a carbonyl compound.
Classification, Nomenclature and structural isomerism of organic compound Ganesh Mote
Classification of organic compound, Nomenclature of alkane, alkene, alkyne, alcohol, alkyl halide, aldehyde, ketone, carboxylic acid and its derivatives, amines, ethers, polyfunctional groups and structural isomerism of organic compounds
Basic concepts of chemistry, alkanes, alkenes, alkynes, benzene, their preparation methods, properties and uses are explained. Isomerism in alkanes and alkynes also discussed.
Alkenes Final chemicals can lead to the opposite product result, but the reactive-intermediate structures and mechanisms are different.Hydrobromic acid in particular is prone to forming radicals in the presence of various impurities or even atmospheric oxygen, leading to the reversal of the Markovnikov result.
This is the presentation about alkanes including its properties ,nomenclature,preparation,reaction and its importance to our everyday lives.
This is very important to education. It is used during our reports in order to learn.
Thus by opening this document you can learn about naming alkanes and cycloalkanes. It is also helpful in preparation in order to identify its importance. I hope that all of you will download this presentation.
Hydrocarbons, the fundamental compounds of organic chemistry, are composed of hydrogen and carbon atoms. The diverse world of hydrocarbons is neatly categorized based on their structure and the type of bonds they contain. In Class 11, students delve into the classification of hydrocarbons, exploring alkanes, alkenes, alkynes, and aromatic compounds.
In Class 11 Chemistry, hydrocarbons serve as a fundamental topic within organic chemistry. Hydrocarbons are organic compounds composed exclusively of carbon and hydrogen atoms. The class primarily focuses on four major types of hydrocarbons: alkanes, alkenes, alkynes, and aromatic hydrocarbons.
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The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptxMAGOTI ERNEST
Although Artemia has been known to man for centuries, its use as a food for the culture of larval organisms apparently began only in the 1930s, when several investigators found that it made an excellent food for newly hatched fish larvae (Litvinenko et al., 2023). As aquaculture developed in the 1960s and ‘70s, the use of Artemia also became more widespread, due both to its convenience and to its nutritional value for larval organisms (Arenas-Pardo et al., 2024). The fact that Artemia dormant cysts can be stored for long periods in cans, and then used as an off-the-shelf food requiring only 24 h of incubation makes them the most convenient, least labor-intensive, live food available for aquaculture (Sorgeloos & Roubach, 2021). The nutritional value of Artemia, especially for marine organisms, is not constant, but varies both geographically and temporally. During the last decade, however, both the causes of Artemia nutritional variability and methods to improve poorquality Artemia have been identified (Loufi et al., 2024).
Brine shrimp (Artemia spp.) are used in marine aquaculture worldwide. Annually, more than 2,000 metric tons of dry cysts are used for cultivation of fish, crustacean, and shellfish larva. Brine shrimp are important to aquaculture because newly hatched brine shrimp nauplii (larvae) provide a food source for many fish fry (Mozanzadeh et al., 2021). Culture and harvesting of brine shrimp eggs represents another aspect of the aquaculture industry. Nauplii and metanauplii of Artemia, commonly known as brine shrimp, play a crucial role in aquaculture due to their nutritional value and suitability as live feed for many aquatic species, particularly in larval stages (Sorgeloos & Roubach, 2021).
DERIVATION OF MODIFIED BERNOULLI EQUATION WITH VISCOUS EFFECTS AND TERMINAL V...Wasswaderrick3
In this book, we use conservation of energy techniques on a fluid element to derive the Modified Bernoulli equation of flow with viscous or friction effects. We derive the general equation of flow/ velocity and then from this we derive the Pouiselle flow equation, the transition flow equation and the turbulent flow equation. In the situations where there are no viscous effects , the equation reduces to the Bernoulli equation. From experimental results, we are able to include other terms in the Bernoulli equation. We also look at cases where pressure gradients exist. We use the Modified Bernoulli equation to derive equations of flow rate for pipes of different cross sectional areas connected together. We also extend our techniques of energy conservation to a sphere falling in a viscous medium under the effect of gravity. We demonstrate Stokes equation of terminal velocity and turbulent flow equation. We look at a way of calculating the time taken for a body to fall in a viscous medium. We also look at the general equation of terminal velocity.
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11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
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Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills MN
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
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ANAMOLOUS SECONDARY GROWTH IN DICOT ROOTS.pptxRASHMI M G
Abnormal or anomalous secondary growth in plants. It defines secondary growth as an increase in plant girth due to vascular cambium or cork cambium. Anomalous secondary growth does not follow the normal pattern of a single vascular cambium producing xylem internally and phloem externally.
2. Introduction
Alkanes are aliphatic hydrocarbons having only C−H and C−C
σ-bonds. They can be cyclic or acyclic.
Acyclic alkanes have the molecular formula CnH2+2 (where n =
an integer.) They are also called saturated hydrocarbons
because they have the maximum number of hydrogen atoms
per carbon.
Cyclic alkanes contain carbon atoms joined into a ring. They
have molecular formula CnH2n
They are also known as Paraffins due to low reactivity. The
main source of Compounds are Petroleum.
3. Hybridization Of alkanes
The combination of one s and three p orbitals to form four hybrid orbitals of
equal energy is known as sp3-hybridization. Example: Methane (CH4) molecule.
These sp3-hybridized orbitals are oriented at an angle of 109°28'. When these four sp3 hybrid
orbitals overlaps with four 1s orbitals of hydrogen, a symmetrical tetrahedral shaped
CH4 molecule form.
4. General Reaction of Alkanes
Alkane halogenations is an example of a substitution reaction, a type of reaction
that often occurs in organic chemistry. A substitution reaction is a chemical
reaction in which part of a small reacting molecule replaces an atom or a group of
atoms on a hydrocarbon or hydrocarbon derivative.
C2H6 + Br2 C2H5Br + HBr
A general equation for the substitution of a single halogen atom for one of the
hydrogen atom of an alkane is
R H + X2
R X + H X
5. Methods of Formartion:
The alkanes are prepared by following general methods of
Preparation of this homologous series.
By Catalytic Hydrogenation of Alkenes and Alkynes:
The method involves the hydrogenation of aklene or alkynes in the presence
of catalyst, nickel at about 200-3000C. This reaction is known as
Sabatier and Senderen’s reaction.
CnH2n + H2
Ni
200-3000
C
CnH2n +2
Ni
200-3000
C
ethene
+ H2 H3C CH3
6. By Grignard Reduction:
Alkyl Halide react with magnesium metals in the presence of dry ether to form
alkyl magnesium halide (R-Mg-X) also called Grignard reagent with
subsequently decomposed by water or alcohol to give alkanes.
Eg.
C2H5Br + Mg
Dry
ether C2H5MgBr
C2H5MgBr + HOH C2H6 + Mg
Br
OH
By Wurtz reaction:
When 2 molecule of alkyl halide react with two atoms of sodium in dry ether , a
higher alkane is obtained.
Other metals like Cu, Ag, in a finely divided state may also be used in place of
sodium.
H3C Cl + 2Na + Cl CH3
(C2H5)O
H3C CH3 + 2 NaCl
7. Limitation
These reaction is not suitable for preparation of unsymmetrical alkanes .
Mechanism:
•Ionic mechanism through intermediate formation
R X + 2Na RNa + NaX
R + R X R R + X
•Free Radical mechanism
R R + Na R + NaX
R + R R R
8. CuLi
R
R + R' X R R' + RCu + LiX R
R Li + Cu X
(C2H5)2O
RCu + LiX
Li R + Cu R [R Cu R] Li
R2Cu+ R' X [R2CuR'X-
] R R' +RCu+RCu + X
By Corey-House synthesis:
The coupling reaction is a good synthetic way to join two alkyl groups together to
produce higher alkanes. This versatile method is known as the Corey-House reaction.
•Mechanism
9. Halogenation of Alkanes
A halogenation reaction is a chemical reaction between a substance and a
halogen in which one or more halogen atoms are incorporated into molecules of
the substance.
Halogenation of an alkane produces a hydrocarbon derivative in which one or
more halogen atoms have been substituted for hydrogen atoms. Alkanes are
notoriously unreactive compounds because they are non-polar and lack
functional groups at which reactions can take place. Free radical halogenation
therefore provides a method by which alkanes can be functionalized. A severe
limitation of radical halogenation however is the number of similar C-H bonds
that are present in all but the simplest alkanes, so selective reactions are
difficult to achieve.
10. General Features of Halogenation of Alkanes
Note the following features of halogenation of alkanes.
•The notation R-H is a general formula for an alkane. R in this case represents an
alkyl group. Addition of a hydrogen atom to an alkyl group produces the parent
hydrocarbon of the alkyl group.
•The notation R-X on the product side is the general formula for a halogenated
alkane. X is the general symbol for a halogen atom.
•Reaction conditions are noted by placing these conditions on the equation arrow
that separates reactants from products. Halogenation of an alkane requires the
presence of heat or light.
11. Chlorination of Methane by Substitution
In halogenation of an alkane, the alkane is said to undergo fluorination,
chlorination, bromination or iodination depending on the identity of the
halogen reactant. Chlorination and bromination are the two widely used
alkane halogenation reactions. Fluorination reactions generally proceed
too quickly to be useful and iodination reactions go too slowly.
Halogenations usually result in the formation of a mixture of products
rather than a single product. More than one product results because
more than one hydrogen atom on an alkane can be replaced with
halogen atoms.
Methane and chlorine when heated to a high temperature in the
presence of light react as follows.
CH4
Cl2
hv
CH3Cl + HCl
Cl2
hv
CH2Cl2 + HCl
Cl2
hv
CHCl3 + HCl
Cl2
hv
CCl4 + HCl
12. The mechanism for this reaction takes place in three steps.
1. Initiation Step:
The Cl-Cl bond of elemental chlorine undergoes hemolysis when irradiated with
UV light, and this process yields two chlorine atoms, also called chlorine radicals.
Cl Cl
hv
(Ultraviolet
light)
2 Cl
2. Propagation Step:
A chlorine radical abstracts a hydrogen atom from methane to produce the
methyl radical. The methyl radical in turn abstracts a chlorine atom from a
chlorine molecule and chloromethane is formed. The second step of propagation
also regenerates a chlorine atom. These steps repeat many times until
termination occurs.
CH3Cl + Cl2 CH2Cl2 + HCl
CH2Cl2 + Cl2 CHCl3 + HCl
CHCl3 + Cl2 CCl4 + HCl
Heat
Heat
Heat
13. 3. Termination Step:
Termination takes place when a chlorine atom reacts with another chlorine atom to
generate Cl2, or chlorine atom can react with a methyl radical to form chloromethane
which constitutes a minor pathway by which the product is made. Two methyl radicals
can also combine to produce ethane, a very minor by product of this reaction.
Cl CH4 H Cl + C H
H
H
Cl Cl C H
H
H Cl + C H
H
H
H
The reaction does not stop at this step, however because the chlorinated
methane product can react with additional chlorine to produce polychlorinated
products.
C H
H
H
Cl
+ C H
H
H
H
Cl Cl Cl
C
H
H
H
C
H
H
H
C2H6
Cl
By controlling the reaction conditions and the ratio of chlorine to methane. It is
possible to favour formation of one or another of the possible chlorinated methane
products.
14. Uses of Alkanes
•Alkanes are important raw materials of the chemical industry and the principal
constituent of gasoline and lubricating oils. Natural gas mainly contains methane
and ethane and is used for heating and cooking purposes and for power utilities
(gas turbines). For transportation purposes, natural gas may be liquefied by
applying pressure and cooling it (LNG = liqid natural gas).
•Crude oil is separated into its components by fractional distillation at oil refineries.
The different "fractions" of crude oil have different boiling points and consist
mostly of alkanes of similar chain lengths (the higher the boiling point the more
carbon atoms the components of a particular fraction).
•The following table provides a short survey of the different fractions of crude oil:
•Propane and butane can be liquefied at fairly low pressures, and are used, for
example, in the propane gas burner, or as propellants in aerosol sprays. Butane is
used in cigarette lighters (where the pressure at room temperature is about 2 bar).
•The alkanes from pentane to octane are highly volatile liquids and good solvents
for nonpolar substances. They are used as fuels in internal combustion engines.
15. •Alkanes from nonane to hexadecane are liquids of higher viscosity, being used in
diesel and aviation fuel (kerosene). The higher melting points of these alkanes
can cause problems at low temperatures and in polar regions, where the fuel
becomes too viscous.
•Alkanes with 17 to 35 carbon atoms form the major components of lubricating oil.
They also act as anti-corrosive agents, as their hydrophobic nature protects the
metal surface from contact with water. Solid alkanes also find use as paraffin wax
in candles.
•Alkanes with a chain length above 35 carbon atoms are found in bitumen (as it is
used in road surfacing). These higher alkanes have little chemical and commercial
value and are usually split into lower alkanes by cracking.
•
•Methane can co-crystallize with water at high pressures and low temperatures,
forming a solid methane hydrate. The energy content of the known submarine
methane hydrate fields exceeds that of all known natural gas and oil deposits put
together.
Editor's Notes
Properties
By Wurtz reaction:
When 2 molecule of alkyl halide react with two atoms of sodium in dry ether , a higher alkane is obtained.
Other metals like Cu, Ag, in a finely divided state may also be used in place of sodium.
Limitation
These reaction is not suitable for preparation of unsymmetrical alkanes .
Mechanism:
Ionic mechanism through intermediate formation
Free Radical mechanism
General Features of Halogenation of Alkanes
Note the following features of halogenation of alkanes.
The notation R-H is a general formula for an alkane. R in this case represents an alkyl group. Addition of a hydrogen atom to an alkyl group produces the parent hydrocarbon of the alkyl group.
The notation R-X on the product side is the general formula for a halogenated alkane. X is the general symbol for a halogen atom.
Reaction conditions are noted by placing these conditions on the equation arrow that separates reactants from products. Halogenation of an alkane requires the presence of heat or light.
2. Propagation Step:
A chlorine radical abstracts a hydrogen atom from methane to produce the methyl radical. The methyl radical in turn abstracts a chlorine atom from a chlorine molecule and chloromethane is formed. The second step of propagation also regenerates a chlorine atom. These steps repeat many times until termination occurs.
By controlling the reaction conditions and the ratio of chlorine to methane. It is possible to favour formation of one or another of the possible chlorinated methane products.
By controlling the reaction conditions and the ratio of chlorine to methane. It is possible to favour formation of one or another of the possible chlorinated methane products.