This chapter discusses sensation and perception. It defines sensation as the process by which sensory receptors receive stimulus energy and perception as organizing and interpreting sensory information. The chapter covers the basic principles of psychophysics and thresholds. It describes sensation in different sensory modalities like vision, audition, touch, taste, smell, and the senses of body position and movement. For each sense modality, it discusses the receptors, neural pathways, processing in the brain, and examples of thresholds, adaptation and interactions between the senses.