The document discusses the potential for 3D printing of oral drugs to help address issues arising during the COVID-19 pandemic. It provides an introduction to 3D printing, describing its history and various applications such as in biomedicine and healthcare. The document then discusses how 3D printing of drugs could help with dose changes for pediatric/geriatric patients, clinical trials of multi-drug combinations, and decentralized production in areas impacted by supply chain problems during the pandemic. It concludes by citing references examining personalizing drug products using 3D printing and how 3D printing could help fight future crises like COVID-19.

1. BY: Dr. Mourad Raafat
Assistant professor of computer science faculty of
science Helwan university and SRGE member
3D printing drugs during
current COVID-19 pandemic

2. Agenda
• Introduction and Motivation
• Applications
• Can 3D printing of oral drugs help fight the current
COVID-19 pandemic?
• Reference

3. Introduction

4. Introduction and Motivation

5. What is 3D printing?
• Using a general-purpose machine
to create a physical object, where
the design of the structure is
provided to the machine at build-
time.
• Usually, the object is created
additively, in a layer-by-layer
process.

6. Components
•Polymers Machines
•Metal Machines
•Ceramics Machines
•Electronics
•Desktop machines
•Design and CAD
Software
•Workflow Software
•Security Software
•Fused deposition modelling(FDM)
•Powder bed fusion
•Inkjet printing and contour crafting
•Stereolithography
•Metal and Alloys
•Polymers
•Ceramic
•Concrete
Material Methods
HardwareSoftware

7. History
• By Charles Hulls in 1986 in a process called
Stereolithography (SLA).
• By the end of 1990, other methodologies
such as Fused Deposition Modelling (FDM)
• In 1993, Massachusetts Institute of
Technology (MIT) patented another
technology named "3 Dimensional Printing
techniques", which is similar to the inkjet
technology used in 2D Printers.

8. Applications

9. • Biomaterial and healthcare
– Represent 11% of AM(from 6.1 bil $ to 21 bil $).
• Aerospace
– Represent 18.2% of AM
• Building
– Represent 3% of AM
• Protective structures
• Agriculture
• Historical

10. Drug printing Advantages

11. Application of drug 3D
printing
• Dose Changes and Geriatric/ Paediatric
Patients
• Clinical Trials
• Multi Drugs
• Global Health

12. Can 3D printing of oral drugs help fight the
current COVID-19 pandemic?
• 3DP has the potential to allow flexible and
decentralized drug production in disease hot spots
where there are insufficient supply chains and logistical
infrastructure
• Individual consumers stockpiling and hoarding
medicines such as chloroquine, antibiotics, vitamin C,
and vitamin E in unregulated markets for home use in
the event they or their family members become ill with
COVID-19

13. Reference
• Trenfield S, Basit A, “Personalising Drug Products Using 3D
Printing”. ONdrugDelivery Magazine, Issue 99 (Aug 2019), pp 28-
32. http://staging.ondrugdelivery.com/personalising-drug-products-using-3d-printing/
• Wen-Kai Hsiao ,Barbara Lorber &Amrit Paudel, “Can 3D printing
of oral drugs help fight the current COVID-19 pandemic (and
similar crisis in the future)?”, Journal Of Expert opinion in drug
delivery https://doi.org/10.1080/17425247.2020.1772229