Jornada científica NanoFrontMag - 21 de junio de 2016 - IMDEA Nanociencia Laboratorio 282 Julio Camarero

1. NanoMagLab provides services for both preparation and characterization of magnetic
nanostructures, in the form of thin films and multilayers -extended or nanopatterned- as
well as magnetic nanoparticles.
The service makes available to the consortium specific advanced instrumentation for
preparation (by physical and chemical means), manipulation (ultrafast-ball milling and
lithography) and characterization (including morphological, structural, electronic, magnetic,
and transport studies) of magnetic nanostructures.
( A ) Biomedical applications: magnetic nanoparticles.
( B ) Information technology: thin films and multilayers, spintronic/spin-orbitronic.
( C ) Automotive: magnetic devices based on next-generation permanent magnets .
( D ) Recycling: magnetic materials processing.
Red de Laboratorios e Infraestructuras de Madri+d (Redlab. 282)

2. Zetasizer Nano ZS (Malvern Instruments): tamaño, peso molecular, potencial Zeta
Chemical synthesis
Thermal decomposition of an iron organic precursor
Magnetite (Fe3O4) MNPs
Hydrodynamic sizes DMSA
coated,(water disp) 42-66 nm

3. Multi-purpose UHV growth/spectroscopy Lab
Four interconnected UHV chambers: (sputtering+MBE+ XPS/UPS+TDS)

4. Vectorial magnetometries
v-VSM v-Kerr
3.5 T,
M||, M
aH = 0º-360º
100 K- RT
> 1memu
GMM-CSIC/ GNB-IMDEA, in preparation
0,3 T,
M||, M
aH= 0º-360º
5 K- 500 K
> 0,1 nm
LASUAM/NanoMagLab-IMDEA
Cuñado et al Rev Sci. Instrum. 86, 046109 (2015)
Phys. Rev. Lett. 95, 057204 (2005); Phys. Rev. B 86, 024421 (2012)

5. UV-visible spectroscopy. Quantify the efficiency of biofunctionalization of NPs, by determining the
structure and stability of biomolecules (DNA , RNAi and antibodies) before & after their conjugation.
Cary 5000 UV - VIS -NIR , with temperature controller and Peltier thermostat.
Purchased in 2015 from other IMDEA projects.
New commercial equipment
UV-Infrared spectroscopy (IR). To quickly determine the presence or absence of functional ,
inorganic and organic groups on the surface of magnetic nanoparticles.
Bruker FT -IR ALPHA system with ATR module, frequency range : 25000 - 50 cm -1, and fast and
accurate measurement system of solid and liquid samples.
Just ordered (June 2016).

6. New home-made equipment
Induction
electromagnet
Thermometer
Magnetic fluid
Heat capacity [W/grFe] = SAR = Area x frequency
AC calorimetry AC magnetometry
Appl. Phys. Lett. 101, 062413 (2012);
J. Phys. Chem. C 119, 15698 (2015) to be published (2016)
pick-up coils
magnetic fluid
1Hz–0,5MHz
0–60mT
ACinductor
SAR= specific absorption rate  dT/dt
Appl. Phys. Rev. 2, 041302 (2015)

7. New home-made equipment
Induction
electromagnet
Thermometer
Magnetic fluid
Heat capacity [W/grFe] = SAR = Area x frequency
AC calorimetry AC magnetometry
to be published (2016)
pick-up coils
magnetic fluid
1Hz–0,5MHz
0–60mT
ACinductor
f < 1 kHz non-hysteretic
f > 10 kHz hysteretic
SAR= specific absorption rate  dT/dt
Appl. Phys. Rev. 2, 041302 (2015)
Appl. Phys. Lett. 101, 062413 (2012);
J. Phys. Chem. C 119, 15698 (2015)

8. g-force induced giant efficiency of nanoparticles
internalization into living cells
Scientific Reports | 5:15160 | (2015) DOI: 10.1038/srep15160
Direct incubation CMI
5 min.
CMI results in controllable cellular uptake efficiencies at least three orders of magnitude
larger than current procedures. The methodology is easily transferable to any laboratory with
great potential for the development of improved biomedical applications (see video).
GNB-IMDEA / GBE-CSIC/ HM
50 mg/ml IONPs
Centrifugated Mediated Internalization
(CMI) promotes a high uptake of iron
oxide nanoparticles (IONPs) in living cells,
just in a few minutes, and via clathrin-
independent endocytosis pathway

9. pinned
soft
I +
I 
V V +
lens
Wollastone
prism
/2 plate
H
eN
e
laser
lens
m0H
a
M||
M
photodiodes
pinned
soft
I +
I 
V V +
lens
Wollastone
prism
/2 plate
H
eN
e
laser
H
eN
e
laser
lens
m0H
a
M||
M
photodiodes
Unique experimental set-up that allows to measure simultaneously magneto-resistance
(MR) and vectorial-resolved Kerr hysteresis loops (M|| and M) at different applied field
angles in the whole angular range.
CIP geometry
I [250mA] // e.a.
Appl. Phys. Lett. 86, 024421 (2014); PRB 92, 220422(R) (2015)
NanoMagLab-IMDEA/LASUAM/

10. Simultaneous v-Kerr + MR
Direct experimental determination of the anisotropic
magnetoresistive effects
Uniaxial magnetic anisotropy system
Appl. Phys. Lett. 104, 202407 (2014)

11. AIP Advances 6, 055819 (2016)
Interfacial exchange-coupling induced
chiral symmetry breaking of Spin-Orbit effects…
FM/AFM systems
exchange-biased spin-valve
Simultaneous v-Kerr + MR
PRB 92, 220422(R) (2015)
Phys. Rev. B 86, 024421 (2012)
see movie

12. Rebeca AmaroLeonor de la CuevaDavid Cabrera
Hyperthermia NPM synthesis
RE-free PMs Spintronic/OMBE
Noelia López Sergio L. de las Heras
Fondo de garantía juvenil

13. Síntesis de NPs (CoFe2O4 (CFO), Magnetita Fe3O4)
Model systems: NEXMAG (Mn-based alloys), SOGRAPH (gr-based spin-orbitronics),
SKYTRON (skyrmion-based spintronics), …
C- Sistema v-M(R)OKE de temperatura variable (5 K- 500K), para poder correlacionar
propiedades magnéticas y magnetoresistivas durante transiciones magnéticas.
D- Magnetometría para estudiar dinámica magnética de nanoparticulas magnéticas
dispersas en medios acuosos o internalizadas en matrices biológicas (células o
tejidos) a través de la medida de los ciclos de imanación en condiciones dinámicas,
procesos íntimamente relacionados con la disipación térmica de las nanopárticulas en
régimen dinámico.
E- Generador portátil de campos magnéticos alternos sintonizable en frecuencia
(hasta 200 kHz) y amplitud de campo (hasta 60 mT), para estudios in-vitro e in-vivo de
hipertermia magnética.