This is the first material of the Drug and Food Interaction for the 2nd year students of Department of Nutrition at Health Polytechnic of Pangkalpinang.

1. The Basic Principal of Drugs and Food
Interaction
DRUGAND FOODINTERACTION
Poltekkes Kemenkes Pangkalpinang
Emmy Kardinasari, S.Si., M.Sc.

2. What is metabolism?

4. METABOLISM AND DIET
• Metabolism can be variative from one individuals compared to
others
• However, we have recommended daily intake or Angka Kecukupan
Gizi (AKG) that can be used as the general concensus for the
Indonesian population.
• In specific case, the daily intake need for each individuals can be
significantly different.
• For example:
• People with sickness
• People with autoimmune
• People metabolic disease
• Kids with malnutrition of wasting and stunting

7. dietitiansource.com

9. What is a drug?
•A chemical substance, especially one prescribed by
a medical provider, that is used in the diagnosis,
treatment, or prevention of a condition or disease.
•All of the active chemical substances that can
be produced from biological source of synthetic
• Drug is produced to cure diseases.
•Drug must e used under medical professionals.
•Many drugs are being illegally used

10. Pharmachology (Farmakologi)
• Pharmachology is a branch of medicine that deals with the
interaction of drugs with the systems and processes of living
animals, in particular, the mechanisms of drug action as well
as the therapeutic and other uses of the drug.
• Pharmacon (drug) and logos (Science or knowledge).
• Farmakologi berasal dari kata pharmacon (obat) dan logos (ilmu
pengetahuan). Farmakologi didefinisikan sebagai ilmu yang mempelajari
obat dan cara kerjanya pada sistem biologis. Farmakognosi adalah ilmu
yang mempelajari tentang interaksi obat, sistemnya, dan proses yang
terjadi di dalam tubuh organisme. Dalam farmakologi juga dipelajari
tentang mekanisme dan efek pengobatan.

11. Farmakologi

12. •Medication
•To achieve systemic
counter to disease
•To cure disease
•To control
biochemical
parameter in the
body
The purpose of consuming drugs or medicine?

13. THE EFFECT OF DRUG AND FOOD INTERACTION

14. • Increase Activity (Peningkatan aktivitas
obat)
• Insulin – Alcohol (treatement diabetes)
• Statins – grapefruit (obat kolesterol)
• Calcium channel blocker – grapefruit
(obat jantung)
• Obata erektil - grapefruits
• Decrease Activity (Penurunan aktivitas
obat)
• Warfarin – vitamin K (pengencer darah)
• Digoxin – serat (obat jantung)
• Tetrasiklin – produk susu (antibiotik)
• Produce toxic / adverse responses
• Asetaminofen – alkohol produksi toksin
liver
• Monoaminosin oksidase – tiramin
menyebabkan peningkatan tekanan
darah
THE EFFECT OF DRUG AND FOOD INTERACTION

15. TERIMA KASIH 