33. Medical Management: Antispasmodics These prescription-only medicines help decrease the muscle spasms that cause urgency to urinate. Painkillers Pain-relieving drugs help treat symptoms of burning and urgency. They may be available over-the-counter (often called OTC drugs) or by prescription only . Cystitis is almost always treated with medication. These medications include: • O ral antibiotics • P ainkillers • A ntispasmodics Oral Antibiotics Oral antibiotics are the most common medications used to treat cystitis. They kill the bacteria that are causing the infection.
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