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HYPERTENSION 
Dr.SARANYA VINOTH
INTRODUCTION 
• Hypertension (high blood preassure) also 
called silent killer is a chronic medical condition 
characterized by constant elevation of the systolic 
or diastolic pressure above 140/90 mmHg. 
• Because hypertension is almost 
without symptoms except for headaches in some 
patients, it hides in the body without knowing it. 
•The fact that hypertension is asymptomatic makes it 
difficult for patients to accept the diagnosis and comply 
with treatment.
INTRODUCTION 
 In India more than over 140 million people 
are believed to be suffering from high blood 
pressure in the country and the number is 
expected to cross the 214 million mark in 
2030. 
 Hypertension is a major risk factor for 
cardio-vascular diseases.
OBJECTIVES 
 At the end of this presentation you should 
understand 
 Define,classify and diagnosis of 
hypertension 
 Types of HT 
 Identify risk factors &complications 
 Treatment guidelines 
 Complications and prevention methods
DEFINITION 
 Hypertension is defined as a systolic blood 
pressure (SBP) of 140 mm Hg or more, or a 
diastolic blood pressure (DBP) of 90 mm 
Hg.
Blood pressure is the force applied against the walls of 
the arteries as the heart pumps blood through the body. 
The pressure is determined by the force and amount of 
blood pumped and the size and flexibility of the arteries.
PATHOPHYSIOLOGY
CAUSES &RISK FACTORS
TYPES 
 Primary Hypertension-unknown 
etiology 
 Secondary Hypertension-due to some 
other medical condition 
 Hypertension in pregnancy 
 Malignant Hypertension with end 
organ damage 
 Paraoxysmal Hypertension
SIGNS AND SYMPTOMS 
 Severe headache 
 Nausea or vomiting 
 Bad headache 
 Confusion 
 Changes in your vision 
 Nosebleeds
Investigations 
 Blood pressure evaluation 
 Fasting Blood Sugar (FBS) – To 
diagnose diabetes 
 Lipid Profile – To diagnose 
dyslipidaemia 
 Renal Profile- Serum Urea, Albumin, 
Creatinine
Measurement of BP 
 The patient must be properly prepared 
and positioned 
 Caffeine,exercise and smoking should 
be avoided for atleast 30 minutes 
before. 
 Average of atleast three readings on 
three different occassions should be 
recorded.
MANAGEMENT
MANAGEMENT 
LIFE STYLE MODIFICATION 
 Regular physical activity 
 Smoking cessation 
 Salt restriction 
 Alcohol cessation 
 Weight loss
MANAGEMENT 
DIETARY PLAN 
 DASH-Dietary Approach to Stop 
Hypertension
MEDICATIONS
A-B-C-D Blood Pressure 
Medications: 
A: ACE inhibitors (angiotensin converting enzyme)prevent the formation 
of the hormone angiotensin 2 which causes blood vessels to become 
narrow making the vessels relax, becoming wider, lowering your blood 
pressure. 
B: Beta Blockers reduce nerve impulses to the heart and blood vessels 
making the heart beat slower with less force to drop your blood pressure 
and the heart doesn't work a hard. 
C: Calcium channel blockers block calcium from entering the muscle cells 
of the heart and blood vessels making them relax and lowering your blood 
pressure. 
D: Diuretics, or water pills, work in the kidney by flushing out excess water 
and sodium from the body.
Beta Blocker 
ATENOLOL 
 Decreases myocardial contractility 
 Fall in cardiac output 
 Decreases blood pressure 
 Additionally it reduces renin secretion 
Dosage- 
 Atenolol 25-100mg once daily
Beta Blocker 
ADVERSE EFFECTS- 
Bradycardia 
Congestive heart disease 
Aggravates asthma 
Sleep alteration 
CONTRAINDIATIONS:- 
 Asthma 
 Diabetes mellitus 
 Heart block 
 Hyperlipidemia
ACE INHIBITORS 
Enalapril 
 Acts by inbiting the conversion of 
angiotensin 1 to angiotensin 2 thus 
preventing the vasoconstriction 
 Used in diabetics. 
Dosage 
 Initial dose (oral): 5 mg orally once a day. 
 Maintenance dose (oral): 10 to 40 mg orally 
per day in 1 to 2 divided doses.
ACE INHIBITORS 
Side effects- 
 First dose hypotension 
 Dry cough 
 Urticaria 
Contraindiation 
 Renal failure 
 Pregnancy
CALCIUM CHANNEL BLOCKER 
Amlodipine 
 Acts by relaxing the smooth muscle in 
the arterial wall, decreasing total peripheral 
resistance thereby reducing blood pressure; 
in angina, amlodipine increases blood flow 
to the heart muscle. 
 Initial dose: 2.5 -5 mg orally once a day 
Maintenance dose: 5 to 10 mg orally once a 
day
CALCIUM CHANNEL BLOCKER 
Side effects- 
 Headache 
 Edema 
 Fatigue 
 Nausea 
 Dizziness 
 Muscle cramps 
Contraindications- 
 Pregnancy 
 Breast feeding
TREATMENT IN DIABETICS 
Measured in clinic Mean daytime ABPM 
or home measurement 
Blood Pressure No diabetes Diabetes No diabetes Diabetes 
Optimal <140/85 <140/80 <130/80 <130/75 
Audit Standard <150/90 <140/85 <140/85 <140/80
FOLLOW UP 
 Urine analysis-albumin,sugar 
 Complete blood count 
 Lipid profile 
 Glucose levels 
 Ophthalmic examination 
 ECG
THANK YOU

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Hypertension

  • 2. INTRODUCTION • Hypertension (high blood preassure) also called silent killer is a chronic medical condition characterized by constant elevation of the systolic or diastolic pressure above 140/90 mmHg. • Because hypertension is almost without symptoms except for headaches in some patients, it hides in the body without knowing it. •The fact that hypertension is asymptomatic makes it difficult for patients to accept the diagnosis and comply with treatment.
  • 3. INTRODUCTION  In India more than over 140 million people are believed to be suffering from high blood pressure in the country and the number is expected to cross the 214 million mark in 2030.  Hypertension is a major risk factor for cardio-vascular diseases.
  • 4. OBJECTIVES  At the end of this presentation you should understand  Define,classify and diagnosis of hypertension  Types of HT  Identify risk factors &complications  Treatment guidelines  Complications and prevention methods
  • 5. DEFINITION  Hypertension is defined as a systolic blood pressure (SBP) of 140 mm Hg or more, or a diastolic blood pressure (DBP) of 90 mm Hg.
  • 6. Blood pressure is the force applied against the walls of the arteries as the heart pumps blood through the body. The pressure is determined by the force and amount of blood pumped and the size and flexibility of the arteries.
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  • 15. TYPES  Primary Hypertension-unknown etiology  Secondary Hypertension-due to some other medical condition  Hypertension in pregnancy  Malignant Hypertension with end organ damage  Paraoxysmal Hypertension
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  • 19. SIGNS AND SYMPTOMS  Severe headache  Nausea or vomiting  Bad headache  Confusion  Changes in your vision  Nosebleeds
  • 20. Investigations  Blood pressure evaluation  Fasting Blood Sugar (FBS) – To diagnose diabetes  Lipid Profile – To diagnose dyslipidaemia  Renal Profile- Serum Urea, Albumin, Creatinine
  • 21. Measurement of BP  The patient must be properly prepared and positioned  Caffeine,exercise and smoking should be avoided for atleast 30 minutes before.  Average of atleast three readings on three different occassions should be recorded.
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  • 24. MANAGEMENT LIFE STYLE MODIFICATION  Regular physical activity  Smoking cessation  Salt restriction  Alcohol cessation  Weight loss
  • 25. MANAGEMENT DIETARY PLAN  DASH-Dietary Approach to Stop Hypertension
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  • 29. A-B-C-D Blood Pressure Medications: A: ACE inhibitors (angiotensin converting enzyme)prevent the formation of the hormone angiotensin 2 which causes blood vessels to become narrow making the vessels relax, becoming wider, lowering your blood pressure. B: Beta Blockers reduce nerve impulses to the heart and blood vessels making the heart beat slower with less force to drop your blood pressure and the heart doesn't work a hard. C: Calcium channel blockers block calcium from entering the muscle cells of the heart and blood vessels making them relax and lowering your blood pressure. D: Diuretics, or water pills, work in the kidney by flushing out excess water and sodium from the body.
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  • 31. Beta Blocker ATENOLOL  Decreases myocardial contractility  Fall in cardiac output  Decreases blood pressure  Additionally it reduces renin secretion Dosage-  Atenolol 25-100mg once daily
  • 32. Beta Blocker ADVERSE EFFECTS- Bradycardia Congestive heart disease Aggravates asthma Sleep alteration CONTRAINDIATIONS:-  Asthma  Diabetes mellitus  Heart block  Hyperlipidemia
  • 33. ACE INHIBITORS Enalapril  Acts by inbiting the conversion of angiotensin 1 to angiotensin 2 thus preventing the vasoconstriction  Used in diabetics. Dosage  Initial dose (oral): 5 mg orally once a day.  Maintenance dose (oral): 10 to 40 mg orally per day in 1 to 2 divided doses.
  • 34. ACE INHIBITORS Side effects-  First dose hypotension  Dry cough  Urticaria Contraindiation  Renal failure  Pregnancy
  • 35. CALCIUM CHANNEL BLOCKER Amlodipine  Acts by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance thereby reducing blood pressure; in angina, amlodipine increases blood flow to the heart muscle.  Initial dose: 2.5 -5 mg orally once a day Maintenance dose: 5 to 10 mg orally once a day
  • 36. CALCIUM CHANNEL BLOCKER Side effects-  Headache  Edema  Fatigue  Nausea  Dizziness  Muscle cramps Contraindications-  Pregnancy  Breast feeding
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  • 39. TREATMENT IN DIABETICS Measured in clinic Mean daytime ABPM or home measurement Blood Pressure No diabetes Diabetes No diabetes Diabetes Optimal <140/85 <140/80 <130/80 <130/75 Audit Standard <150/90 <140/85 <140/85 <140/80
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  • 41. FOLLOW UP  Urine analysis-albumin,sugar  Complete blood count  Lipid profile  Glucose levels  Ophthalmic examination  ECG
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