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PHARMACOLOGY
SUBMITTED TO:
Dr Huma Riaz
SUBMITTED BY:
Mehrwar Hijab
MANAGING HYPERTENSION
BP Increase
Baroreceptors sense
pressure
Stimulateα2 receptors
in Brainstem
Decrease Sympathetic
discharge
Decrease TPR,
Decrease CO
BP decrease
MANAGING HYPOTENSION
_________________________________
↓ BP
↑ Sympathetic
activity
Actvation of β21
adrenoreceptors
of the heart
↑ cardiac output
Activation of α1
adrenoreceptors
of smooth muscle
↑ peripheral
resistance
↓ Renal blood
flow
↑ Renin
↑ Angiotensin II
↑ Aldosterone
↓ Glomerular
filtration rate
↑ Sodium, water
retention
↑ Blood volume
↑ BP

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Managing hypertension & hypotension