2. Kawasaki disease
• It is a acute febrile muco-cutaneous lymph node
syndrome mainly affecting infants and young
children
• Diagnosis criteria
• A) fever lasting for At least 5 days
• B)presence of any 4 of the following conditions
3. daignosis
• Bilateral non purulent conjuctival injection
• Changes of mucosal oropharynx ex; injected pharynx,
injected lips, strawberry Tongue
• Changes of peripheral extremities;
• 1)acute stage ; EDEMA, ERETHEMA OF HANDS OR FEET
• 2)convalescent stage: desquamation usually bigin
periungually
• Polymorphous rash
• Cervical lymphadenopathy
5. Kawasaki disease
• Most children have high grade fever and
irritable this irritability provide first clue for its
diagnosis
• Beau lines seen in convalescent phase
• Basic lesion is necrotising vasculitis of medium
sized muscular arteries which may result in
aneurysms,dilatations,and stenoses
6. Treatment
• Single dose immunoglobulin 2g/kg
• Aspirin anti inflammatory dose75-80mg/kg
until afebrile
• Aspirin 3-5mg/kg/day continued for few
weeks