Kidney transplantation involves transplanting a kidney from a living or deceased donor into a patient with end-stage renal disease. There are two key factors in renal transplantation - the recipient with kidney failure, and the donor who can be a living donor under 60 years old or a deceased donor. The document outlines types of grafts, nursing interventions like monitoring urine output and kidney function tests, potential for graft rejection, and lifelong immunosuppressive therapy to reduce rejection risk.

2. Kidney transplantation or renal transplantation is
the organ transplant of a kidney into a patient with
end-stage renal disease.

3.  There are two important factor in renal
transplantation.
 Recipient: Patient with ESRD
 Donor< 60years:
 Living Donor Cadevar donor
o HLA Brain Death
o ABO HR
o Malignancy RR Normal
o STD urine output
o Hepatitis + Living donor
o HIV

4. Types of graft

5. Nursing Intervention
Donor consent
Psychological support for donor and recipient.
Avoid the crowded place.
Recipient should be on hemodialysis before 24 hours
of renal transplantation.
Closely monitoring of recipient urine output in 15 min
in beginning and later on 1 hourly.
We should check creatinine level and blood urea level.
Closely monitoring of tenderness, bleeding and fever.

6. Graft rejection
 Graft rejection is characterized b tenderness, itching,
fever, restlessness, increase creatinine level, decrease
urine output.
There are three type of graft rejection
i. Hyper acute: <24 hours
ii. Acute : 6 weeks to 1.5 month
iii. Chronic : Month to years

7. Management
 To reduce the chance of graft rejection wee should
start corticosteroids and immunosuppressive therapy
like sirolimus and tacrolimus for life long