Nano biotechnology (3rd generation)

1. Presented by
C. Karthiksaran
II- M.Sc., Botany
Periyar University,
Salem- 636 011.
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2.  The process of creating living, physiological, three
dimensional tissues and organs utilizing specific
combinations of cells, cell scaffold and cell signals, both
chemical and mechanical.
(OR)
 Tissue engineering covers the wide range of applications
that repairs or replace the portion of damaged tissues like
bone, cartilage, blood vessels, skin and bladder.
 Producing better organ used for transplantation.
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3.  Biomaterials serve as an integral component of tissue
engineering.
 They are designed to provide architectural
framework reminiscent of native extracellular
matrix in order to encourage cell growth and
eventual tissue regeneration.
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4.  To induce cellular migration or tissue regeneration
 To encapsulate cells and act as an immuno- isolation
barrier
 To provide a matrix to support cell growth and cell
organization.
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5.  Cells- by means of stem cell culture.
 Scaffold- metals, ceramics, polymer
◦ Growth and development of cells provides mechanical
strength. Scaffold is of 2 types,
 Synthetic scaffold,
 Natural scaffold.
 Signaling molecules- growth factors, hormones,
morphogenetic proteins
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