Abstract
Frequent Knee Locking is an incapacitating condition that requires a thorough clinical, radiological and arthroscopic evaluation. The common causes are meniscal injury followed by torn anterior cruciate ligament and osteochondral loose bodies in the joint space. Our case describes an unusual case of frequent left knee locking. After clinical and radiological examinations the provisional diagnoses of medial meniscus tear was done. A diagnostic arthroscopy of the left knee revealed normal meniscus, cruciates and a medial patello femoral plica slipping into the patellofemoral joint causing the locking sensation. The plica was resected. At 6 month follow up there is no recurrence of symptoms.
Shoulder dislocations are the most common joint dislocations, and only 2% of these are seen as posterior shoulder dislocations. The floating elbow was first described in children, after that shown in adults. Floating elbow cases are very rare, and usually seen with high-energy trauma. Classical definition is the coexistence of the humeral diaphyseal and forearm fracture, but there are other definitions as well.
An isolated posterior dislocation of radial head in adults - A rare injury: A...Apollo Hospitals
An isolated posterior dislocation of radial head in adults is a rare injury. We report a 32-year-old male patient with posterior dislocation of radial head associated with articular fracture fragment of the radial head. Open reduction and internal fixation with a miniscrew was done and patient had excellent outcome at a follow up of 2 years.
An isolated posterior dislocation of radial head in adults – A rare injury: A...Apollo Hospitals
An isolated posterior dislocation of radial head in adults is a rare injury. We report a 32-year-old male patient with posterior dislocation of radial head associated with articular fracture fragment of the radial head. Open reduction and internal fixation with a miniscrew was done and patient had excellent outcome at a follow up of 2 years.
Abstract
Frequent Knee Locking is an incapacitating condition that requires a thorough clinical, radiological and arthroscopic evaluation. The common causes are meniscal injury followed by torn anterior cruciate ligament and osteochondral loose bodies in the joint space. Our case describes an unusual case of frequent left knee locking. After clinical and radiological examinations the provisional diagnoses of medial meniscus tear was done. A diagnostic arthroscopy of the left knee revealed normal meniscus, cruciates and a medial patello femoral plica slipping into the patellofemoral joint causing the locking sensation. The plica was resected. At 6 month follow up there is no recurrence of symptoms.
Shoulder dislocations are the most common joint dislocations, and only 2% of these are seen as posterior shoulder dislocations. The floating elbow was first described in children, after that shown in adults. Floating elbow cases are very rare, and usually seen with high-energy trauma. Classical definition is the coexistence of the humeral diaphyseal and forearm fracture, but there are other definitions as well.
An isolated posterior dislocation of radial head in adults - A rare injury: A...Apollo Hospitals
An isolated posterior dislocation of radial head in adults is a rare injury. We report a 32-year-old male patient with posterior dislocation of radial head associated with articular fracture fragment of the radial head. Open reduction and internal fixation with a miniscrew was done and patient had excellent outcome at a follow up of 2 years.
An isolated posterior dislocation of radial head in adults – A rare injury: A...Apollo Hospitals
An isolated posterior dislocation of radial head in adults is a rare injury. We report a 32-year-old male patient with posterior dislocation of radial head associated with articular fracture fragment of the radial head. Open reduction and internal fixation with a miniscrew was done and patient had excellent outcome at a follow up of 2 years.
Benefits of Mechanical Manipulation of the Sacroiliac Joint: A Transient Syno...CrimsonPublishersOPROJ
Benefits of Mechanical Manipulation of the Sacroiliac Joint: A Transient Synovitis Case Study by Brady Hauser* in Crimson Publishers: Orthopedic Research and Reviews Journal
comminuted fracture of left patellar with displacement case presentationJOEL RAJAN U
A patella fracture is a break of the kneecap. Symptoms include pain, swelling, and bruising to the front of the knee. A person may also be unable to walk. Complications may include injury to the tibia, femur, or knee ligaments. It typically results from a hard blow to the front of the knee or falling on the knee.
Abstract
Objective: To assess the outcome of arthroscopic release in patients with cronicalchronic lateral epicondylitis. Materials and methods: Arthroscopic release in three patients with lateral epicondylitis was performed. The Mayo Elbow Performance Index (or Mayo Elbow Performance score) was used pre and post surgical treatment. Sample: Two females and one male. The patients were principal labourers and not athletes. Patients had significant pain and pain was the principal symptom that affected the score of the performance index.
Results: Scores on the performance index improved after surgery. No neurological complications were reported and early return to normal daily activities was noted.
Conclusion: Arthroscopic treatment was an alternative safe and effective method for treating chronic lateral epicondiyitis in three cases. This method makes it possible to simultaneously scan the articulation to diagnostic and treatment associated diseases. It is necessary most wide assays and comparative studies for establish sure treatment protocols.
Sportsman’s hernia is a complex entity with injuries occurring at different levels in the groin region. Each damaged anatomical structure gives rise to a different set of symptoms and signs making the diagnosis difficult. The apprehension of a hernia is foremost in the mind of the surgeon. Absence of a hernia sac adds to the confusion. Hence awareness of this condition is essential for the general surgeon to avoid misdiagnosis.
Effectiveness of Progressive Inhibition of Neuromuscular Structures (PINS) an...MusaDanazumi
Abstract- Background and aim: Lumbar disc herniation with radiculopathy has been one of the most difficult conditions to manage in orthopedic manual therapy. While there are many clinical studies concerning the standardization of surgical treatment, there is to date no standardized literatures for the most effective non-operative care for lumbar disc herniation with radiculopathy which suggest that extreme measures to ameliorate lumbar disc herniation with radiculopathy are urgently warranted. In this study, a 35 year old man who was diagnosed with lumbar disc herniation and was planned for lumbar surgery due to failure of medical interventions was successfully treated using non-operative management.
Method: The management of the patient included Progressive Inhibition of Neuromuscular Structures (PINS), Spinal Mobilization with Leg Movement (SMWLM) and Therapeutic exercises inform of lumbar stabilization and stretching exercises. The patient was seen three times in a week over the period of 6 weeks after which the patient was discharged home without having lumbar surgery. Patient was assessed before and after treatments and during one and two year follow-ups using; Visual Analogue Scale (VAS) in the back and leg, Sciatica Bothersome Index (SBI), Sciatica Frequency Index (SFI) and Rolland-Morris Disability Questionnaire (RMDQ) for sciatica.
Results: After six weeks of management the patient had decreased in functional limitation (from 19 to 6), back pain (from 8 to 0), leg pain (from 10 to 2), sciatica frequency (from 18 to 8) and sciatica bothersomeness (from 18 to 8). These outcomes were maintained after one and two year follow-ups.
Conclusion: Progressive inhibition of neuromuscular structures and spinal mobilization with leg movement are effective in the management of patients diagnosed with lumbar disc herniation with radiculopathy.
Implication: Progressive inhibition of neuromuscular structures and spinal mobilization with leg movement may be considered as useful therapeutic non-operative measures for patients diagnosed with lumbar disc herniation with radiculopathy.
Index Terms- Progressive Inhibition of Neuromuscular Structures; Spinal Mobilization with Leg Movement; Lumbar Disc Herniation with Radiculopathy.
Non-union fracture neck femur in a young patientApollo Hospitals
Fracture neck of femur in young is rare and usually occur
due to severe injuries like road traffic accident (RTA), fall from height etc. If the displaced fractures are not treated early, then it is often associated with complications. Non-union is one of the commonest complications. Treatment of non-union of these fractures in young is quite challenging.
Benefits of Mechanical Manipulation of the Sacroiliac Joint: A Transient Syno...CrimsonPublishersOPROJ
Benefits of Mechanical Manipulation of the Sacroiliac Joint: A Transient Synovitis Case Study by Brady Hauser* in Crimson Publishers: Orthopedic Research and Reviews Journal
comminuted fracture of left patellar with displacement case presentationJOEL RAJAN U
A patella fracture is a break of the kneecap. Symptoms include pain, swelling, and bruising to the front of the knee. A person may also be unable to walk. Complications may include injury to the tibia, femur, or knee ligaments. It typically results from a hard blow to the front of the knee or falling on the knee.
Abstract
Objective: To assess the outcome of arthroscopic release in patients with cronicalchronic lateral epicondylitis. Materials and methods: Arthroscopic release in three patients with lateral epicondylitis was performed. The Mayo Elbow Performance Index (or Mayo Elbow Performance score) was used pre and post surgical treatment. Sample: Two females and one male. The patients were principal labourers and not athletes. Patients had significant pain and pain was the principal symptom that affected the score of the performance index.
Results: Scores on the performance index improved after surgery. No neurological complications were reported and early return to normal daily activities was noted.
Conclusion: Arthroscopic treatment was an alternative safe and effective method for treating chronic lateral epicondiyitis in three cases. This method makes it possible to simultaneously scan the articulation to diagnostic and treatment associated diseases. It is necessary most wide assays and comparative studies for establish sure treatment protocols.
Sportsman’s hernia is a complex entity with injuries occurring at different levels in the groin region. Each damaged anatomical structure gives rise to a different set of symptoms and signs making the diagnosis difficult. The apprehension of a hernia is foremost in the mind of the surgeon. Absence of a hernia sac adds to the confusion. Hence awareness of this condition is essential for the general surgeon to avoid misdiagnosis.
Effectiveness of Progressive Inhibition of Neuromuscular Structures (PINS) an...MusaDanazumi
Abstract- Background and aim: Lumbar disc herniation with radiculopathy has been one of the most difficult conditions to manage in orthopedic manual therapy. While there are many clinical studies concerning the standardization of surgical treatment, there is to date no standardized literatures for the most effective non-operative care for lumbar disc herniation with radiculopathy which suggest that extreme measures to ameliorate lumbar disc herniation with radiculopathy are urgently warranted. In this study, a 35 year old man who was diagnosed with lumbar disc herniation and was planned for lumbar surgery due to failure of medical interventions was successfully treated using non-operative management.
Method: The management of the patient included Progressive Inhibition of Neuromuscular Structures (PINS), Spinal Mobilization with Leg Movement (SMWLM) and Therapeutic exercises inform of lumbar stabilization and stretching exercises. The patient was seen three times in a week over the period of 6 weeks after which the patient was discharged home without having lumbar surgery. Patient was assessed before and after treatments and during one and two year follow-ups using; Visual Analogue Scale (VAS) in the back and leg, Sciatica Bothersome Index (SBI), Sciatica Frequency Index (SFI) and Rolland-Morris Disability Questionnaire (RMDQ) for sciatica.
Results: After six weeks of management the patient had decreased in functional limitation (from 19 to 6), back pain (from 8 to 0), leg pain (from 10 to 2), sciatica frequency (from 18 to 8) and sciatica bothersomeness (from 18 to 8). These outcomes were maintained after one and two year follow-ups.
Conclusion: Progressive inhibition of neuromuscular structures and spinal mobilization with leg movement are effective in the management of patients diagnosed with lumbar disc herniation with radiculopathy.
Implication: Progressive inhibition of neuromuscular structures and spinal mobilization with leg movement may be considered as useful therapeutic non-operative measures for patients diagnosed with lumbar disc herniation with radiculopathy.
Index Terms- Progressive Inhibition of Neuromuscular Structures; Spinal Mobilization with Leg Movement; Lumbar Disc Herniation with Radiculopathy.
Non-union fracture neck femur in a young patientApollo Hospitals
Fracture neck of femur in young is rare and usually occur
due to severe injuries like road traffic accident (RTA), fall from height etc. If the displaced fractures are not treated early, then it is often associated with complications. Non-union is one of the commonest complications. Treatment of non-union of these fractures in young is quite challenging.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists
Complete volar dislocation.pdf
1. International Journal of Orthopaedic Trauma 1994;4: 80
Complete volar dislocation of the
proximal interphalangeat joint of the
nftle finger
F O HASSAN
Summary
A complete volar dislocation of the proximal inter-
phalangeal (PIP) joint of a little finger occurred in a 52-
year-old man and was successfully treated by closed
reduction and a dynamic PIP extension splint.
Case report
A 52-year-old male stumbled while descending stairs and
fell down on his left hand.
Examination revealed flexion of the PlPjoint and extension
of the distal interphalangeal joint of the left little finger, with
no radial or ulnar deviation of the finger. There was no active
movement of the finger, nor neurovascular deficit; an X-ray
showed complete dislocation of the PIP joint (Figure 1).
Reduction was performed under entonox by traction and
extension. The collateral ligaments were stable after
reduction, but the joint was unstable in flexion of the finger.
A dynamic PIP extension splint with metacarpophalangeal
joint support was applied for six weeks, then a night splint
for four weeks. Regular follow-up for 14 months showed full
range of movement of the finger, no ligamentous laxity, nor
any residual deformity.
Discussion
Volar dislocation of the PlPjoint is a very rare injury compared
to the dorsal dislocation. Only L2 cases of this type have
been described in the literature,r-s and all were irreducible
due to soft tissue interposition or osteochondral fragment.
All of the reported cases necessitated open reduction.
The mechanism of the injury in our case was hyperflexion
force to the middle phalanx, although Spinner and Choi
found that a varus or valgus force was necessary to cause the
injury.s
Figure L Complete volar dislocation of the PIP joint of
the little finger.
There was no mention in the literature about the reducible
volar dislocation of the PIP, apart from the higher incidence
of the rupture of the extensor mechanism which needed to be
repaired, but this case showed that conservative treatment
may have a role.
References
1. Johnson FG, Greene MH. Another cause of irreducible
dislocation of the PIPJ of a finger. J Bone Joint Surg (Am)
1966; 482 542-4.
2. Inoue G, Maeda N. Irreducible palmar dislocation of the PIP
joint of the finger. Report 3 cases. J Hand Surg 1990; 15A:
301-4,
3. Murakami Y. Ireducible volar dislocation of the PIP joint of
the finger. Hand 1974; 6: 87-90.
4. Martin AP, Michael W. Irreducible volar dislocation of the
PIPJ of a finger caused by interposition of an intact central
slip. J Bone Joint Surg (Am) 1978; 60: 133-4.
5. Spinner M, Choi BY. Anterior dislocation of the PIPJ. J Bone
Joint Surg (Am) 1970; 52: 1329-36.
Department of Orthopaedic Surgery, University of Jordan, Amman, Jordan
Mr FO Hassan FRCS (Ene)
Correspondence to: Mr FO Hassan FRCS (Eng), Orthopaedic Registrar, Robert Jones
and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SYl0 7AG, UK.
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