Describe andor draw the lymphatic system from capillariesto the mai.pdf

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Describe and/or draw the lymphatic system from capillariesto the main lymphatic ducts; include the specializedintestinal lymphatic drainage; explain what chyle is, whereit comes from and why it can only collect in the leftchest, not right, after chest trauma. Solution Lymphatic system: Explain what chyle is, whereit comes from and why it can only collect in the leftchest, not right, after chest trauma. Lymph from the intestinal trunk, referred to as chyle, drains into the lower end of the thoracic duct. Whenever there is trauma to the thoracic, it may cause a leak in the thoracic duct, and effuse se the chyle lymphatic fluid in the pleural space. Chyle appears in the left side because drainage from all parts of the body except the upper quadrant is collected into the thoracic which is on the left side. Pain is also therefore experienced only on the left, not the right side..

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Thoracic duct  Lymph duct: • A lymph duct is a great lymphatic vessel that empties lymph into one of the subclavian veins. • There are two lymph ducts in the body the right lymphatic duct and the thoracic duct. • The right lymphatic duct drains lymph from the right upper limb, right side of thorax and right halves of head and neck. • The thoracic duct drains lymph into the circulatory system at the left brachiocephalic vein between the left subclavian and left internal jugular veins.  Thoracic duct: • In human anatomy, the thoracic duct is the larger of the two lymph ducts of the lymphatic system. It is also known as the left lymphatic duct, alimentary duct, chyliferous duct, and Van Hoorne's canal. • The thoracic duct is the largest lymphatic vessel in the human body. Around 75% of the lymph from the entire body passes through the thoracic duct. • The other duct is the right lymphatic duct. The thoracic duct carries chyle, a liquid containing lymph and emulsified fats, rather than pure lymph. • It also collects most of the lymph in the body other than from the right thorax, arm, head, and neck (which are drained by the right lymphatic duct).  Structure: • In adults, the thoracic duct is typically 38 – 45 cm in length and has an average diameter of about 5 mm. • The vessel usually starts from the level of the twelfth thoracic vertebra (T12) and extends to the root of the neck. • It drains into the systemic (blood) circulation at the angle of the left subclavian and internal jugular veins as a single trunk, at the commencement of the brachiocephalic vein • The thoracic duct originates in the abdomen from the confluence of the right and left lumbar trunks and the intestinal trunk, forming a significant pathway upward called the cisterna chyli. • It traverses the diaphragm at the aortic aperture, and ascends the superior and posterior mediastinum between the descending thoracic aorta (to its left) and the azygos vein (to its right). • The duct extends vertically in the chest and curves posteriorly to the left carotid artery and left internal jugular vein. • At the T5 vertebral level it crosses the midline to the left side. It ascends further to terminate into the systemic (blood) circulation at the venous angle of the left subclavian and internal jugular veins i.e. the commencement of the brachiocephalic vein, below the clavicle, near the shoulders.  Area of drainage: • The thoracic duct drains the lymph from all the parts of the body with the exception of  Right side of the head and neck  Right side of the chest wall  Right lung  Right side of the heart  Right surface of the liver.  The right upper quadrant of the body that is drained by the right lymphatic duct.  Function: • The thoracic duct collects most of the lymph in the body other than from the right thorax, arm, head, and neck. • The lymph transport, in the thoracic duct, is mainly caused by the action of breathing, aided by the duct's smooth muscle

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Cardiac lymphatic capillaries form complicated networks with ramifications and anastomosis13 and can be found in subepicardium, myocardium, and subendocardium. The direction of lymphatic drainage is from subendocardial lymphatics toward the subepicardial lymphatics, eventually leading to the mediastinal lymph nodes. Fluid that is forced out of the bloodstream during normal circulation is filtered through lymph nodes to remove bacteria, abnormal cells and other matter. This fluid is then transported back into the bloodstream via the lymph vessels. Lymph only moves in one direction, toward the heart. The lymphatic plexus in the epicardium is characterized by the presence of thinner initial lymphatics or capillaries consisting of a single layer of lymphatic endothelial cells (LECs). These highly permeable vessels are critical to drain macromolecules, extracellular fluid, and cells (lymph). The biochemical make up of lymph — the fluid found in the lymphatic vessels — varies with the site of origin. For example, lymph from bone marrow, spleen, and thymus have high concentrations of white blood cells for fighting infection, while lymph from intestines is high in fat that has been absorbed during digestion. Damage to the lymphatic and circulatory systems leaves the body more susceptible to sickness and infection, as well as to serious conditions such as cancer. As most of the cells in the human body are not in direct contact with the external environment, the circulatory system acts as a transport system for these cells. Two distinct fluids move through the circulatory system: blood and lymph. Blood carries oxygen and nutrients to the body's cells, and carries waste materials away. Blood also carries hormones, which control body processes, and antibodies, to fight invading germs. The heart is the pump that keeps this transport system moving. Together, the blood, heart, and blood vessels form the circulatory system. The lymphatic system (lymph, lymph nodes and lymph vessels) supports the circulatory system by draining excess fluids and proteins from tissues back into the bloodstream, thereby preventing tissue swelling. It also serves as a defense system for the body, filtering out organisms that cause disease, producing white blood cells, and generating antibodies. The mammalian circulatory system comprises both the cardiovascular system and the lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a unidirectional transit pathway from the extracellular space to the venous system. It actively regulates tissue fluid homeostasis, absorption of gastrointestinal lipids, and trafficking of antigen-presenting cells and lymphocytes to lymphoid organs and on to the systemic circulation. The cardinal manifestation of lymphatic malfunction is lymphedema. Recent research has implicated the lymphatic system in the pathogenesis of cardiovascular diseases including obesity and metabolic disease, dyslipidemia, inflammation.

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