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LYMPH
 What is lymph ?
Tissue fluid (interstitial fluid) that
enters the lymphatic vessels
FORMATION AND TRANSPORT
OF TISSUE FLUID
Essentially a
drainage system
accessory to venous
system
larger particles that escape
into tissue fluid can only be
removed via lymphatic
system
LYMPHATIC SYSTE
Functions of the Lymphatic
System
24-
4
 Reabsorbs excess interstitial fluid:
 returns it to the venous circulation
 maintain blood volume levels
 prevent interstitial fluid levels from rising out of
control.
 Transport dietary lipids:
 transported through lacteals
 drain into larger lymphatic vessels
 eventually into the bloodstream.
 lymphocyte development, and the immune
Components of the Lymphatic
System24-
5  Lymph
 Lymphatic Vessels
 Lymphatic Capillaries
 Lymphatic Vessels
 Lymphatic Trunks
 Lymphatic Ducts
 Lymphatic Organs
 Thymus
 Lymph Nodes
 Spleen
 Tonsils
 Lymphatic cells
Lymph Vessels
 Lymphatic capillaries –
 Lymphatic collecting vessels
 Lymphatic trunks –
 Lymphatic ducts –
Lymphatic Capillaries
24-
8
Features of structure:
 Blind end
 Single layer of overlapping
endothelial cells
 More permeable than that of
blood capillary
 Absent from avascular
structures, brain, spinal cord
splenic pulp and bone
marrow
Lymphatic Capillaries – Lacteals
24-
9
 The small intestine contains special
types of lymphatic capillaries called
lacteals.
 Lacteals pick up not only interstitial
fluid, but also dietary lipids and lipid-
soluble vitamins.
 The lymph of this area has a milky
color due to the lipid and is also called
Lymphatic Vessels
24-
10
Features of
structure
Three layered wall
but thinner than vein,
More numerous
valves than in vein
Interposed by lymph
nodes at intervals
Arranged in
superficial and deep
LYMPH TRUNKS
 right and left jugular trunks
 right and left subclavian
trunks
 right and left
bronchomediastinal trunks
 right and left lumbar trunks
LYMPHATIC DUCTS
24-
12
Right lymphatic duct
 Formed by union of
right jugular,
subclavian, and
bronchomediastinal
trunks
 Ends by entering the
right venous angle
Thoracic duct
 Begins in front of L1 as a
dilated sac, the cisterna
chyli,
 formed by left and right
lumbar trunks and
intestinal trunk
 Enter thoracic cavity &
ascends
 Travels upward, veering
LYMPHATIC
DUCTS
14
THORACIC DUCT…..
 At the root of the neck,
it turns laterally
 arches forwards and
descends to enter the
left venous angle
 before termination, it
receives the left
jugular, Subclavian
and broncho-
mediastinal trunk
DRAINAGE PATTERN
THORACIC DUCT -
Drains lymph from lower
limbs, pelvic cavity,
abdominal cavity, left
side of thorax, and left
side of the head, neck
RIGHT LYMPHATIC DUCT
-Receives lymph from
right half of head, neck,
thorax and right upper
limb, right lung, right side
of heart, right surface of
liver
Lymphatic Cells
24-
16
 Also called lymphoid cells.
 Located in both the lymphatic system
and the cardiovascular system.
 Work together to elicit an immune
response.
 Types of lymphatic cells are:
 macrophages
 epithelial cells
 dendritic cells
 lymphocytes
LYMPHATIC ORGANS
Primary organs
Red bone marrow
Thymus gland
Secondary organs
Lymph nodes
Lymph nodules
Spleen
Lymph
Nodes24-
18 Small, round or oval
 located along the
pathways of lymph
vessels.
 length from 1 - 25
millimeters
 Typically found in
clusters
 receive lymph from
many body regions.
 Lymph nodes are also
19
Spleen
Location
Left epigastric region
between 9th-11th rib
in line of 10th rib
 Largest lymphatic organ in
the body.
 Can vary considerably in
size and weight
Function
20
THYMUS
Features
 Consists of two
elongated lobes
 Is a large organ in
the fetus
 Occupies the
thoracic cavity
behind the sternum
 Secrete
lymphopoietin
Lymphatic Nodules
24-
21 Oval clusters of lymphatic cells with some
extracellular matrix that are not surrounded by a
connective tissue capsule.
 Filter and attack antigens.
 In some areas of the body, many lymphatic nodules
group together to form larger structures.
 mucosa-associated lymphatic tissue (MALT) or
tonsils
 very prominent in the mucosa of the small intestine,
primarily in the ileum
Peyer patches
Tonsils
24-
22
 clusters of lymphatic cells and extracellular
matrix not completely surrounded by a
connective tissue capsule.
 Consist of multiple germinal centers and
crypts
 Several groups of tonsils form a protective
ring around the pharynx.
pharyngeal tonsils (or adenoids) in
nasopharynx
palatine tonsils in oral cavity
lingual tonsils along posterior one-third of
MALT (Mucosa Associated
Lymphoid Tissue)23
Name the structures labelled
A-E.
QUESTION. 1
 I am a part of lymphatic system and protect
the body by clearing worn out red cells and
foreign bodies from the blood stream. Who
am I?
A. Thymus
B. Palatine
Tonsil
C. Spleen
QUESTION. 2
Which is the correct statement about the
Lymphatic system?
A. It Reabsorbs excess interstitial fluid and
returns it to the venous circulation.
B. Transports dietary lipids through lacteals.
C. Helps in lymphocyte development, and the
immune response.
D. All of the above
QUESTION. 3
 Which of these is a primary lymphoid
organ ?
A. Lymph Node
B. Spleen
C. Tonsil
D. Bone Marrow
QUESTION. 5

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Lymphatic System Functions and Components

  • 1. LYMPH  What is lymph ? Tissue fluid (interstitial fluid) that enters the lymphatic vessels
  • 3. Essentially a drainage system accessory to venous system larger particles that escape into tissue fluid can only be removed via lymphatic system LYMPHATIC SYSTE
  • 4. Functions of the Lymphatic System 24- 4  Reabsorbs excess interstitial fluid:  returns it to the venous circulation  maintain blood volume levels  prevent interstitial fluid levels from rising out of control.  Transport dietary lipids:  transported through lacteals  drain into larger lymphatic vessels  eventually into the bloodstream.  lymphocyte development, and the immune
  • 5. Components of the Lymphatic System24- 5  Lymph  Lymphatic Vessels  Lymphatic Capillaries  Lymphatic Vessels  Lymphatic Trunks  Lymphatic Ducts  Lymphatic Organs  Thymus  Lymph Nodes  Spleen  Tonsils  Lymphatic cells
  • 6. Lymph Vessels  Lymphatic capillaries –  Lymphatic collecting vessels  Lymphatic trunks –  Lymphatic ducts –
  • 7.
  • 8. Lymphatic Capillaries 24- 8 Features of structure:  Blind end  Single layer of overlapping endothelial cells  More permeable than that of blood capillary  Absent from avascular structures, brain, spinal cord splenic pulp and bone marrow
  • 9. Lymphatic Capillaries – Lacteals 24- 9  The small intestine contains special types of lymphatic capillaries called lacteals.  Lacteals pick up not only interstitial fluid, but also dietary lipids and lipid- soluble vitamins.  The lymph of this area has a milky color due to the lipid and is also called
  • 10. Lymphatic Vessels 24- 10 Features of structure Three layered wall but thinner than vein, More numerous valves than in vein Interposed by lymph nodes at intervals Arranged in superficial and deep
  • 11. LYMPH TRUNKS  right and left jugular trunks  right and left subclavian trunks  right and left bronchomediastinal trunks  right and left lumbar trunks
  • 12. LYMPHATIC DUCTS 24- 12 Right lymphatic duct  Formed by union of right jugular, subclavian, and bronchomediastinal trunks  Ends by entering the right venous angle
  • 13. Thoracic duct  Begins in front of L1 as a dilated sac, the cisterna chyli,  formed by left and right lumbar trunks and intestinal trunk  Enter thoracic cavity & ascends  Travels upward, veering LYMPHATIC DUCTS
  • 14. 14 THORACIC DUCT…..  At the root of the neck, it turns laterally  arches forwards and descends to enter the left venous angle  before termination, it receives the left jugular, Subclavian and broncho- mediastinal trunk
  • 15. DRAINAGE PATTERN THORACIC DUCT - Drains lymph from lower limbs, pelvic cavity, abdominal cavity, left side of thorax, and left side of the head, neck RIGHT LYMPHATIC DUCT -Receives lymph from right half of head, neck, thorax and right upper limb, right lung, right side of heart, right surface of liver
  • 16. Lymphatic Cells 24- 16  Also called lymphoid cells.  Located in both the lymphatic system and the cardiovascular system.  Work together to elicit an immune response.  Types of lymphatic cells are:  macrophages  epithelial cells  dendritic cells  lymphocytes
  • 17. LYMPHATIC ORGANS Primary organs Red bone marrow Thymus gland Secondary organs Lymph nodes Lymph nodules Spleen
  • 18. Lymph Nodes24- 18 Small, round or oval  located along the pathways of lymph vessels.  length from 1 - 25 millimeters  Typically found in clusters  receive lymph from many body regions.  Lymph nodes are also
  • 19. 19 Spleen Location Left epigastric region between 9th-11th rib in line of 10th rib  Largest lymphatic organ in the body.  Can vary considerably in size and weight Function
  • 20. 20 THYMUS Features  Consists of two elongated lobes  Is a large organ in the fetus  Occupies the thoracic cavity behind the sternum  Secrete lymphopoietin
  • 21. Lymphatic Nodules 24- 21 Oval clusters of lymphatic cells with some extracellular matrix that are not surrounded by a connective tissue capsule.  Filter and attack antigens.  In some areas of the body, many lymphatic nodules group together to form larger structures.  mucosa-associated lymphatic tissue (MALT) or tonsils  very prominent in the mucosa of the small intestine, primarily in the ileum Peyer patches
  • 22. Tonsils 24- 22  clusters of lymphatic cells and extracellular matrix not completely surrounded by a connective tissue capsule.  Consist of multiple germinal centers and crypts  Several groups of tonsils form a protective ring around the pharynx. pharyngeal tonsils (or adenoids) in nasopharynx palatine tonsils in oral cavity lingual tonsils along posterior one-third of
  • 24. Name the structures labelled A-E. QUESTION. 1
  • 25.  I am a part of lymphatic system and protect the body by clearing worn out red cells and foreign bodies from the blood stream. Who am I? A. Thymus B. Palatine Tonsil C. Spleen QUESTION. 2
  • 26. Which is the correct statement about the Lymphatic system? A. It Reabsorbs excess interstitial fluid and returns it to the venous circulation. B. Transports dietary lipids through lacteals. C. Helps in lymphocyte development, and the immune response. D. All of the above QUESTION. 3
  • 27.  Which of these is a primary lymphoid organ ? A. Lymph Node B. Spleen C. Tonsil D. Bone Marrow QUESTION. 5