(1)You are an animal composed of segments, like an earthworm, wasp, or centipede. Your segments are not visible until you remove your skin and look at the muscles of your torso as well as your vertebrae and ribs. Your muscles develop in blocks called somites from your head(anterior) to your tailbone(posterior). Protein signals from the head interact with receptors in cells further down to control the number and size of your somites. One of these signals is delta it binds the receptor Notch. When Delta folds its fold contains units of secondary structure that are repeated, each unit folding on its own. These repeats are called EGF-like repeats. In the final fold these units stack together to make a solenoid shape (a hollow spiraled tube somewhat like a short or partial helix). Which of the following terms are appropriate to describe a single EGF repeat in the chain? Pick ALL that apply. there is more than one answer. super secondary structure secondary structure quarternary structure a structure found in the center of a protein folding funnel tertiary structure domain a structure found at the bottom of a protein folding funnel a structure found at the top of a protein folding funnelA. super secondary structureB. secondary structureC. quarternary structureD. a structure found in the center of a protein folding funnelE. tertiary structureF. domainG. a structure found at the bottom of a protein folding funnelH. a structure found at the top of a protein folding funnel Solution Answer: F. domain; b. secondary structure; H. a structure found at the top of a protein folding funnel Reason: Epidermal growth fcaror is “extracellular domain made of protein of secondary structure in which beta-helices are prominent. So that, it is a membrane ebound protein that is to be secrete with a structure found at the top of a protein folding funnel Amplification and receptor docking research on the tyrosine kinase activity for example quantitative structure activity relationship (QSAR) of the epidermal growth factor receptor enable in finding novel therapies against the tumor metastasis. Constitutive mutation in the epidermal growth factor receptor may leading to stimulation of the phosphoionitidyl – kinases and further produces downstream effects that activate tumor cell division..

1. (1)You are an animal composed of segments, like an earthworm, wasp, or centipede. Your
segments are not visible until you remove your skin and look at the muscles of your torso as well
as your vertebrae and ribs. Your muscles develop in blocks called somites from your
head(anterior) to your tailbone(posterior). Protein signals from the head interact with receptors in
cells further down to control the number and size of your somites. One of these signals is delta it
binds the receptor Notch. When Delta folds its fold contains units of secondary structure that are
repeated, each unit folding on its own. These repeats are called EGF-like repeats. In the final fold
these units stack together to make a solenoid shape (a hollow spiraled tube somewhat like a short
or partial helix). Which of the following terms are appropriate to describe a single EGF repeat in
the chain? Pick ALL that apply. there is more than one answer.
super secondary structure
secondary structure
quarternary structure
a structure found in the center of a protein folding funnel
tertiary structure
domain
a structure found at the bottom of a protein folding funnel
a structure found at the top of a protein folding funnelA.
super secondary structureB.
secondary structureC.
quarternary structureD.
a structure found in the center of a protein folding funnelE.
tertiary structureF.
domainG.
a structure found at the bottom of a protein folding funnelH.
a structure found at the top of a protein folding funnel
Solution
Answer: F. domain; b. secondary structure; H. a structure found at the top of a protein folding
funnel
Reason:
Epidermal growth fcaror is “extracellular domain made of protein of secondary structure in
which beta-helices are prominent. So that, it is a membrane ebound protein that is to be secrete

2. with a structure found at the top of a protein folding funnel
Amplification and receptor docking research on the tyrosine kinase activity for example
quantitative structure activity relationship (QSAR) of the epidermal growth factor receptor
enable in finding novel therapies against the tumor metastasis. Constitutive mutation in the
epidermal growth factor receptor may leading to stimulation of the phosphoionitidyl – kinases
and further produces downstream effects that activate tumor cell division.