Pulmonary TB

Highlights on Pulmonary Tuberculosis Prof. Dr. Saad S Al-Ani Senior Pediatric Consultant Head of Pediatric department Khorfakkan Hospital

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Pulmonary infections Predisposing factors 1.Decreased cough reflex 2.Injury to cilia 3.Decreased function of alveolar macrophages 4.Edema or congestion 5.Retention of secretions

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Typical Progression of Pulmonary tuberculosis ,[object Object],2.Granuloma formation with fibrosis 3.Caseous necrosis ,[object Object],5.Cavity formation

Acid-Fast (Kinyoun) Stain of Mycobacterium

Mycobacterium Tuberculosis Stained with Fluorescent Dye

Not Everyone Exposed Becomes Infected ,[object Object],[object Object],[object Object],[object Object],[object Object],10% of infected persons will develop TB disease at some point in their lives ,[object Object],[object Object]

Treatment of TB Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],Never add a single drug to a failing regimen

Barriers to Adherence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Improving Adherence ,[object Object],[object Object],-Patient education ,[object Object],[object Object],[object Object]

Directly Observed Therapy (DOT) *Health care worker watches patient swallow each dose of medication *DOT is the best way to ensure adherence ,[object Object],Reduces relapse of TB disease and acquired drug resistance

Remember “ A decision to test is a decision to treat.” Thank you

Pulmonary TB

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Pulmonary TB