For sem 7 B.pharm students GTU

1. P R E P A R E D B Y
J A N H A V I S O D H A
S E M – 7 , A P I P J A M N A G A R
G U I D E B Y : M R S . P O O J A K H A N P A R A
GALO

2.  Plant Part Used : stem
 Synonyms : Heartleaved Moonseed , Guduchi.
 Common Vernacular Names
 1) Sanskrit : Anirtavalf , Amrta , Madlitiparni ,
Guducika
 2) Gujarati : Galac , Garo .
 3) Hindi : Giloe , Gurcha .
 4) Kannada : Amrutaballi .

3. Biological source : It is consist of dried , matured
pieces of stem of Tinospora cordifolia Miers.
Family : Menispermaceae.
Distribution : It is an herbaceous vine and
indigenous to the tropical areas of India , Myanmar ,
Shrilanka.
The plant is a glabrous climbing shrub found
throughout India , typically growing in deciduous
and dry forests.

4. Macroscopy
Leaves are heart shaped .
The succulent bark is creamy white to grey with deep
clefts spotted with lenticels.
 flowers are yellow
Fruits are turning red when ripe
Young stems are green in colour
 Stem surfaces are smooth .
Bitter in taste.

6. Microscopy

7.  Cork : 5 to 6 layers thick walled tangentionally
elongated cells with brownish pigments.
 Cortex : It consists of 3 to 5 layers of regularly
arranged cells of chlorenchyama and the inner side
cells are polygonal parenchyma which starch grains .
 Pericycle : 7 to 9 layers of lignified
sclerenchymatous cells , forming a continuous circle
of arches.
 Medullary rays : they are 2 to 8 seriate , 10to12 in
number , extended from pith to the cortex .

8.  Vascular bundles : 16-20 open and collateral.
Consist of :
 1) Phloem : Appear like caps over the metaxylem.
Calcium oxalate crystals present .
 2) Cambium : strip of thin wallled cambium cell.
 3) Xylem : Wedge shaped patches separated by
multiseriate medullary rays . Large number of
lignified pitted xylem vessels. Xylem parenchyma ,
tracheids and xylem fibres are comparatively less.

9. METHOD OF PREPARATION
 Guduchi satva is prepared from root braches and
stem pieces of Tinospora cordifolia .
 Upper thin skin is removed and bruished in stone or
in wooden mortar and ground to paste , soaked in
water for 6-12 hours.
 Material is mashed , rubbed, squeezed and separated
from the fluid by straining later through cloth.
 The fluid is evaporated in the sun and the residue is
genuine “Guduchi Satva”

10. CHENICAL CONSTITUENTS
Columbin , tinosporaside , tetrahydrofuran
Alkaloids like palmatine , berberine , jactrorhizine
,tembeterine.
Tinocordifolioside , cordifolioside A and B
Tinosporic acid , tinosporal , tinosporone.

11. COMMON USE
 Rejuvinator
 Immunodulator
 Astringent
 Antipyretic
 Blood purifier
 Antineoplatic
 Cardiotonic
 Antiasthanatic
 Also use in skin diseases , gout ,rheumatic arthritis.

12. Marketed formulations
 Guduchi tablet
 Abana bomnisan
 Rumalaya