Digitalis purpurea is a species of flowering plant in the plantain family Plantaginaceae, native to and widespread throughout most of temperate Europe. It is also naturalised in parts of North America and some other temperate regions.

1. Harsh Kumar
Baranwal

2. 
a) Digitalis Purpurea
b) Straw foxglove
c) Yellow foxglove
d) Finger flower
e) Fairy bell
Synonyms

3. 
Digitalis consist of dried leaves of
Digitalis Purpurea Linn.
After collection leaves are dried
immediately at temperature below 60 c
They contain no more than 5% moisture.
After drying leaves are stored in
moisture proof container.
BIOLOGICAL
SOURCE

4. 
 Scrophulariacee
Family

5. 
1. Its is found in European
countries,England,France,
2. Germany North America and
India.
3. In India,it is cultivated in
Kashmir and Nilgiri Hill.
GEOGRAPICAL
SOURCE

6. 
 It is a perennial or biennial herb of about 1-2 meters.
 The seed of digitalis are small in size i.e 100 ,so they are
mixed with sand for sowing .
 Favourable temperature range 20-30 c and rainfall 30-40
cm per annum and an altitude of 1600-3000m.
 The seedling is than transplanted into the field.
 Generally the leaves are collected in the afternoon during
August and September ,with a belief that maximum cardio
active glycosides are present at that time.
 The leaves are immediately dried after collection below 60 c
and dried leaves are stored in airtight containers.
 The dried leaves should not contain more than 5% moisture ,
since it promotes hydrolysis of cardiac glycosides resulting in
CULTIVATION AND
COLLECTION

7. 
 Colour -Dark greyish-green
 Odour – Characteristic.
Taste – Bitter.
Size – 10-40 cm long and
4-20 cm wide.
Shape – Ovate-lanceolate .
Margin – Dentate.
Venation – Pinnate.
MACROSCOPICAL
CHARACTERS

8. MACROSCOPIC
CHARACTERS
• Trichomes –
Uniseriate ,
Multicellular and
blunty pointed.
• Stalk – Unicellular.
• Collencyma present at
3 different places i.e
the upper epidermis
,lower epidermis and
pericyclic part.

9. 
Digitalis contain 0.2 – 0.4 % glycosides.
Example – Gitaloxin , Verodoxin
,Digoxin.
It also contain 2 Saponin glycosides viz –
Digitonin , Gitonin.
It contain 2.8-6.2% volatile oil.
1 -10 % fixed oil ex – cineole.
Tannins and pectin.
CHEMICAL
CONSTITUENT

10. 
STRUCTURES

11. 
1. Keller –kiliani test.
2. Legal test.
3. Baljet test.
4. Raymond test.
5. Xanthydrol test.
CHEMICAL TEST

12. 
It is used in the treatment of
congestive heart failure.
Cardiotonic.
 Used in treatment of Artial flutter, trial
fibrillation.
Diuretic in cardiac edema.
USES

13. 
The leaves of Verbascum thapsus.
The Primrose leaves.
Comfrey leaves.(leaves of
Symphytum officinale .
Mullein leaves.(leaves of
Verbascum thapsus Linn).
ADULTERANTS

14. 
MARKETED
FORMULATION

15. 
DRUGS

16. 
MECHANISM OF
ACTION OF DIGITALIS

17. 
Lack of ouabain effect on pacing –induced
myocardial ischemia in patients with coronary
artery disease.(Loeb HS ,et .Am J
Cardiol.1979.)
Effect of digoxin on coronary blood flow and
myocardial oxygen consumption in patients
with chronic coronary artery disease (Kotter
V ,et al.Am J Cardiol 1978.)
The effect of stepwise doses of digitalis on
hemodynamic function in man.(Gould L et
RECENT
ADVANCES IN
DIGITALIS

18. 

19. 

20. ANY QUERY
?