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GENE INTERACTION
UNIT II (B): GENE INTERACTIONS
 Mendel and other workers assumed that characters are governed by single genes but
later it was discovered that many characters are governed by two or more genes.
 Such genes affect the development of concerned characters in various ways; this lead
to the modification of the typical Dihybrid ratio (9:3:3:1) or trihybrid (27:9:9:9:3:3:3:1).
 Numerous deviations have been recorded in which different kinds of interactions are
possible between the genes.
 The phenomenon of two or more genes affecting the expression of each other in various
ways in the development of a single character of an organism is known as GENE
INTERACTION.
 Most of the characters of living organisms are controlled/ influenced/ governed by a
collaboration of several different genes.
 BATESON suggested concept of gene interaction and this concept is called Bateson’s
factor hypothesis.
KINDS OF GENE INTERACTIONS
1. INTRA- ALLELIC GENE INTERACTIONS
 The genetic interactions between the alleles of a single gene are referred to intra-
allelic gene interactions.
 Commonly referred as Intragenic interaction
2. INTER-ALLELIC GENE INTERACTIONS
 The genetic interactions between the alleles of one gene with the allele of other gene
are referred to inter- allelic gene interactions.
 Commonly referred as Intergenic interaction
Some of the interallelic gene interactions to be discussed are tabulated below.
Interallelic gene
interaction
Example Parental
generation
F1
generation
F2
Ratio
A Complementary
gene interaction
Flower color in
Lathyrus odoratus
White X White
ccPP X CCpp
Purple
CcPp
9:7
B Supplementary
gene interaction
Grain color in
Maize
Purple X White
RRPP X rrpp
Purple
RrPp
9:3:4
C Epistasis
i Dominant Epistasis Fruit color in
Cucurbita pepo
White X Yellow
WWyy X wwYY
White
WwYy
12:3:1
ii Recessive Epistasis Coat color in Mice Black X Albino
CCaa X ccAA
Agouti
CcAa
9:3:4
D Non- Epistasis Comb pattern in
Poultry
Rose X Pea
RRpp X rrPP
Walnut
RrPp
9:3:3:1

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1. Gene interaction - Introduction

  • 1. P a g e | 1 GENE INTERACTION UNIT II (B): GENE INTERACTIONS  Mendel and other workers assumed that characters are governed by single genes but later it was discovered that many characters are governed by two or more genes.  Such genes affect the development of concerned characters in various ways; this lead to the modification of the typical Dihybrid ratio (9:3:3:1) or trihybrid (27:9:9:9:3:3:3:1).  Numerous deviations have been recorded in which different kinds of interactions are possible between the genes.  The phenomenon of two or more genes affecting the expression of each other in various ways in the development of a single character of an organism is known as GENE INTERACTION.  Most of the characters of living organisms are controlled/ influenced/ governed by a collaboration of several different genes.  BATESON suggested concept of gene interaction and this concept is called Bateson’s factor hypothesis. KINDS OF GENE INTERACTIONS 1. INTRA- ALLELIC GENE INTERACTIONS  The genetic interactions between the alleles of a single gene are referred to intra- allelic gene interactions.  Commonly referred as Intragenic interaction 2. INTER-ALLELIC GENE INTERACTIONS  The genetic interactions between the alleles of one gene with the allele of other gene are referred to inter- allelic gene interactions.  Commonly referred as Intergenic interaction Some of the interallelic gene interactions to be discussed are tabulated below. Interallelic gene interaction Example Parental generation F1 generation F2 Ratio A Complementary gene interaction Flower color in Lathyrus odoratus White X White ccPP X CCpp Purple CcPp 9:7 B Supplementary gene interaction Grain color in Maize Purple X White RRPP X rrpp Purple RrPp 9:3:4 C Epistasis i Dominant Epistasis Fruit color in Cucurbita pepo White X Yellow WWyy X wwYY White WwYy 12:3:1 ii Recessive Epistasis Coat color in Mice Black X Albino CCaa X ccAA Agouti CcAa 9:3:4 D Non- Epistasis Comb pattern in Poultry Rose X Pea RRpp X rrPP Walnut RrPp 9:3:3:1