Basics for undergraduate/university students
The phenomenon of two or more genes affecting the expression of each other in various
ways in the development of a single character of an organism is known as GENE
INTERACTION.
Recombination DNA Technology (Nucleic Acid Hybridization )
1. Gene interaction - Introduction
1. P a g e | 1
GENE INTERACTION
UNIT II (B): GENE INTERACTIONS
Mendel and other workers assumed that characters are governed by single genes but
later it was discovered that many characters are governed by two or more genes.
Such genes affect the development of concerned characters in various ways; this lead
to the modification of the typical Dihybrid ratio (9:3:3:1) or trihybrid (27:9:9:9:3:3:3:1).
Numerous deviations have been recorded in which different kinds of interactions are
possible between the genes.
The phenomenon of two or more genes affecting the expression of each other in various
ways in the development of a single character of an organism is known as GENE
INTERACTION.
Most of the characters of living organisms are controlled/ influenced/ governed by a
collaboration of several different genes.
BATESON suggested concept of gene interaction and this concept is called Bateson’s
factor hypothesis.
KINDS OF GENE INTERACTIONS
1. INTRA- ALLELIC GENE INTERACTIONS
The genetic interactions between the alleles of a single gene are referred to intra-
allelic gene interactions.
Commonly referred as Intragenic interaction
2. INTER-ALLELIC GENE INTERACTIONS
The genetic interactions between the alleles of one gene with the allele of other gene
are referred to inter- allelic gene interactions.
Commonly referred as Intergenic interaction
Some of the interallelic gene interactions to be discussed are tabulated below.
Interallelic gene
interaction
Example Parental
generation
F1
generation
F2
Ratio
A Complementary
gene interaction
Flower color in
Lathyrus odoratus
White X White
ccPP X CCpp
Purple
CcPp
9:7
B Supplementary
gene interaction
Grain color in
Maize
Purple X White
RRPP X rrpp
Purple
RrPp
9:3:4
C Epistasis
i Dominant Epistasis Fruit color in
Cucurbita pepo
White X Yellow
WWyy X wwYY
White
WwYy
12:3:1
ii Recessive Epistasis Coat color in Mice Black X Albino
CCaa X ccAA
Agouti
CcAa
9:3:4
D Non- Epistasis Comb pattern in
Poultry
Rose X Pea
RRpp X rrPP
Walnut
RrPp
9:3:3:1