This presentation can give you a introductory knowledge about Biosensor.

1. Biosensor
Presented to..
Nazmul Haque Syekat
Department of Fisheries And Marine
Science,NSTU
ID :ASH 1802050M
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2. What is Biosensor ?
Historical Background
Components of Biosensor
Characteristics of Biosensor
Types of Biosensor
Application of Biosensor
Advantages of Biosensor
Conclusion
Flow of Presentation
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3.  A biosensor is an analytical device, used for the
detection of a chemical substance, that combines a
biological component with a physicochemical detector.
 The term biosensor is short for biological sensor. The
device is made up of a transducer and a biological
element that may be an enzyme, an antibody or a
nucleic acid.
 Father of the biosensor Professor Leland C Clark
(1918-2005)
What is Biosensor?
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4. Historical Background
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5. Analyte: A substance of interest that needs detection. For instance,
glucose is an ‘analyte’ in a biosensor designed to detect glucose.
Bioreceptor: A molecule that specifically recognises the analyte is
known as a bioreceptor. Enzymes, cells, DNA and antibodies are
some examples of bioreceptors.
Transducer: The transducer is an element that converts one form of
energy into another. In a biosensor the role of the transducer is to
convert the bio-recognition event into a measurable signal.
Components of Biosensor:
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6. Components of Biosensor (cont..)
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7. Electronics: This is the part of a biosensor that processes the transduced signal
and prepares it for display. It consists of several complex electronic circuit.
Display: The display consists of a user interpretation system such as the liquid
crystal display of a computer or a direct printer that generates numbers or curves
understandable by the user.
Components of Biosensor (cont..)
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8. Selectivity: Selectivity is perhaps the most important feature of a biosensor.
Selectivity is the ability of a bioreceptor to detect a specific analyte in a sample
containing other admixtures and contaminants.
Reproducibility: Reproducibility is the ability of the biosensor to generate identical
responses for a duplicated experimental set-up. The reproducibility is characterised
by the precision and accuracy of the transducer and electronics in a biosensor.
Stability: Stability is the degree of susceptibility to ambient disturbances in and
around the biosensing system.
Characteristics of a biosensor
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9. Sensitivity: The minimum amount of analyte that can be detected by a
biosensor defines its limit of detection (LOD) or sensitivity.
Linearity : Linearity of the biosensor can be associated with the resolution of
the biosensor and range of analyte concentrations under test.
Characteristics of a biosensor(cont..)
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10. The different types of biosensors are classified based on the sensor device as well as
the biological material. Some are discussed below:
Types of Biosensor:
Electrochemical biosensor is based on the reaction of
enzymatic catalysis that consumes or generates
electrons. Such types of enzymes are named as Redox
Enzymes.
The blood glucose Biosensors are used widely
throughout the world for diabetic patients.

11. Types of Biosensor(c0nt..)
Thermometric-biosensor is used to measure or
estimate the serum cholesterol.
The Optical biosensor is a device that uses an optical
measurement principle. These sensors mainly involve
antibodies and enzymes like the transducing elements.
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12. Application of Biosensor:
Fig: Application of Biosensor in different sector

13. Application of Biosensor(c0nt..)
General healthcare monitoring.
Screening for disease.
Clinical analysis and diagnosis of
disease
Veterinary and agricultural
applications.
Industrial processing and monitoring.
Environmental pollution control.
Pollution control and monitoring.
Clinical diagnosis and biomedicine.
Process control: fermentation control
and analysis food and drink.
Production and analysis.
Microbiology: bacterial and viral
analysis.
Pharmaceutical and drug analysis.
Industrial effluent control.
Military applications.

14. Biosensors are used in detecting environmental pollutants and monitoring of
Mines, Industries and toxic gases.
Biosensors are used in the BOD measurement during waste water treatment.
Biosensors are used in the detection of poly aromatic hydrocarbons present in
water.
Environmental applications e.g. the detection of pesticides and river water
contaminants such as heavy metal ions.
Detection and determination of organophosphates.
Biosensor in Environmental sector
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15. A. Biosensors are used in both clinical and laboratory use in medical care.
Glucose monitoring in diabetes patients
Medtronic glucose sensor -implants in major vein of heart
B.Tumor cells are used as biosensors to monitor the susceptibility of
chemotherapeutic drugs.
C. Micro- and nanoscale biosensors
Genome mutation detection, cancer detection & clinical diagnosis
Bacterial-UTI , Human Immunodeficiency Virus (HIV) Detection
Hepatitis and Anthrax detection.
Biosensor in Clinical sector
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16. The key benefits of biosensors include the following:
Rapid and continuous measurement.
High specificity.
Very less usage of reagents required for calibration.
Fast response time.
Ability to measure non-polar molecules that cannot be estimated by other
conventional devices.
Advantages of Biosensor :
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17. We can say that developing a biosensor is related with interdisciplinary study as
Biology, Biochemistry, Chemistry,Electrochemistry, Physics, Kinetics and Mass
transfer knowledge is required for this study Proportional to the technological
development and increase of interdisciplinary studies biosensors are being more
useful and having more usage areas day by day.
Conclusion
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18.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986445/
 https://www.elprocus.com/what-is-a-biosensor-types-of-biosensors-and-
applications/
 https://www.watelectrical.com/biosensors-types-its-working-and-
applications/
 Wikipedia.com/Biosensor
Reference
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