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NUCLEAR ENVELOPE
• Also known as the Nuclear Membrane
• Has 2 separate bilayers
• Has thousands of nuclear pores
• Separates contents of the nucleus from the
cytoplasm
• Provides structure to the nucleus
Structure of Nuclear Envelope
• Outer Membrane
• Continuous to ER
• Has ribosomes
• Cytoplasmic surface
• Perinuclear Space
• Space between inner and outer
membrane
• Lumen of nuclear membrane
• Inner Membrane
• Has nuclear proteins: Laminin, LAP1 &
LAP2, Emerin, and Nurin
• Nuclear Pores
• Protein Channels
• Nuclear Lamina
• Plays role in chromatin organization, cell
cycle regulation, DNA replication and
repair

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Nuclear Envelope

  • 1. NUCLEAR ENVELOPE • Also known as the Nuclear Membrane • Has 2 separate bilayers • Has thousands of nuclear pores • Separates contents of the nucleus from the cytoplasm • Provides structure to the nucleus
  • 2. Structure of Nuclear Envelope • Outer Membrane • Continuous to ER • Has ribosomes • Cytoplasmic surface • Perinuclear Space • Space between inner and outer membrane • Lumen of nuclear membrane • Inner Membrane • Has nuclear proteins: Laminin, LAP1 & LAP2, Emerin, and Nurin • Nuclear Pores • Protein Channels • Nuclear Lamina • Plays role in chromatin organization, cell cycle regulation, DNA replication and repair