AHS / NURSING

1. DR.N.MANJULA

6.  INFLAMMATION OF THE BLOOD VESSELS.

7.  IMMUNE MEDIATED VASCULITIS.
 DIRECT INJURY TO THE VESSELS BY THE ORGANISMS.

8.  SMALL VESSEL VASCULITIS
 MEDIUM VESSEL VASCULITIS
 LARGE VESSEL VASCULITIS

11.  CHRONIC GRANULOMATOUS INFLAMMATION.
 LARGE SIZE VESSELS ARE USUALLY INVOLVED.
 M/C – TEMPORAL, VERTEBRAL AND OPHTHALMIC VESSELS.
 ETIOLOGY – BACTERIAL INFECTION, VIRUS, ANTIBIOTICS AND AUTOIMMUNITY.

12.  INTIMAL THICKENING.
 GRANULOMATOUS INFLAMMATION.
 FRAGMENTATION OF LAMINA.
 LESION IS FOCAL.
 NEGATIVE BIOPSY DO NOT RULE OUT DIAGNOSIS.

13.  FACIAL PAIN.
 HEADACHE.
 DIPLOPIA.

16.  PULSELESS DISEASE.
 WEAKENING OF PULSE IN UPPER EXTREMITIES.
 OCCUR IN PATIENTS YOUNGER THAN 50 YEARS OF AGE.
 FIBROUS THICKENING OF AORTA.
 GRANULOMATOUS INFLAMMATION WITH MONONUCLEAR CELLS IN MEDIA.

17.  REDUCED BP
.
 WEAK PULSE – CAROTIDS, OCULAR VESSELS, UPPER EXTREMITIES.
 VISUAL DEFECT, RETINAL H’GE, BLINDNESS.
 CLAUDICATION OF LEGS.
 PULMONARY HYPERTENSION, MI.
 RENAL INVOLVEMENT – SYSTEMIC HYPERTENSION.

20.  SYSTEMIC VASCULITIS – VISCERAL AND RENAL BLOOD VESSELS.
 PULMONARY VESSELS – NOT INVOLVED.
 IMMUNE COMPLEX DEPOSITION.
 HEPATITIS B INFECTION.

21.  SEGMENTAL TRANSMURAL INFLAMMATION OF SMALL TO MEDIUM SIZED VESSELS.
 WEAKENING OF VESSELS – ANEURYSM FORMATION.
 ACUTE PHASE – TRANSMURAL NECROTIZING INFLAMMATION WITH MIXED
INFLAMMATORY CELLS WITH FIBRINOID NECROSIS.

23.  DISEASE OF YOUNG AGE.
 RAPID ONSET OF HYPERTENSION – RENAL VESSEL INVOLVEMENT, ABDOMINAL PAIN.
 BLOOD TINGED STOOLS – GIT INVOLVEMENT.
 MYALGIA, NEURITIS.

25.  MUCOCUTANEOUS LYMPH NODE SYNDROME.
 AFFECTS CHILDREN.
 LARGE TO MEDIUM SIZED VESSELS.
 VIRAL ETIOLOGY.

26.  MUCOUS MEMBRANE OF CONJUNCTIVA AND ORAL CAVITY.
 BLISTERS WITH DESQUAMATIVE RASH IN HANDS AND FEET – MAINLY PALM AND SOLES.
 ASSOCIATED WITH LYMPHADENITIS.
 GOOD PROGNOSIS.
 CVS AFFECTED – MI.

28.  ACUTE NECROTISING GRANULOMA – SMALL AND MEDIUM SIZED VESSELS.
 c- ANCA POSITIVE.

30.  INVOLVES SMALL VESSELS – NECROTIZING GRANULOMA WITH EOSINOPHILS.
 ALLERGIC ANGITIS.
 ASSOCIATED WITH ASTHMA AND EOSINOPHILIA & ANCA’s.
 MULTISYSTEM DISEASE – SKIN, RENAL, CVS.
 DEATH – HEART INVOLVEMENT.

33.  ALL SYSTEM INVOLVED – SKIN AND MUCOUS MEMBRANE.
 SEGMENTAL NECROTIZING VASCULITIS WITH LEUKOCYTOCLASTIC VASCULITIS.
 AFFECTS CAPILLARIES, SMALL VESSELS.

35.  SEGMENTAL, ACUTE ON CHRONIC DISEASE OF MEDIUM AND SMALL SIZED VESSELS –
THROMBOSIS.
 ARTERIES AND VEINS OF EXTREMITIES ARE AFFECTED.
 YOUNG, MALE SMOKERS, BEFORE 35 TO 40 YEARS.
 ACUTE ON CHRONIC INFLAMMATION OF VESSEL WALL WITH THROMBUS FORMATION.

36.  CLAUDICATION PAIN – LEG, HAND – GANGRENE.
 REST PAIN, DIGITAL ULCERS.
 ASSOCIATED WITH SMOKING.