The document outlines the life cycle of Plasmodium, the parasite that causes malaria. It starts with sporozoites infecting the liver where they multiply and release merozoites. The merozoites then invade red blood cells and undergo asexual reproduction, multiplying into merozoites within the red blood cells. Some parasites develop into gametocytes, the sexual form that can infect mosquitoes to continue the life cycle.

1. SPOROZOITE
MEROZOITE
HYPNOZOITE
TROPHOZOITE
SCHIZONT
GAMETOCYTE
Infective stage of plasmodium – in salivary gland of female
anopheles mosquito
Blood meal – release of sporozoites into human
ASEXUAL HAPLOID FORM
Within liver parasite multiplies
and release merozoites when
each hepatocyte ruptures
Relapse form seen in liver
Released from liver MEROZOITES invade RBC and enter
erythrocytic stage
First stage of parasite in RBC, has SINGLE CHROMATIN MASS
MULTIPLE CHROMATIN MASS,
each develops into Merozoite
On lysis of each RBC new merozoite
infects other RBC
On release of each merozoite  fever,
chiils and rigor
Some parasites develop into
Gametocyte, only infective form
(SEXUAL FORM)
MALARIA LIFE CYCLE